100276-65-1

Basic information

• Product Name: ethyl 6,7,8-trifluoro-1-[formyl(methyl)amino]-4-oxo-1,4-dihydroquinoline-3-carboxylate
• Synonyms: 3-quinolinecarboxylic acid, 6,7,8-trifluoro-1-(formylmethylamino)-1,4-dihydro-4-oxo-, ethyl ester; Ethyl 6,7,8-trifluoro-1-[formyl(methyl)amino]-4-oxo-1,4-dihydroquinoline-3-carboxylate
• CAS NO: 100276-65-1
• Molecular Formula: C₁₄H₁₁F₃N₂O₄
• Molecular Weight: 328.2433
• Mol File: 100276-65-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 429.5°C at 760 mmHg
• Flash Point: 213.6°C
• Density: 1.49g/cm³
• Vapor Pressure: 1.4E-07mmHg at 25°C
• Refractive Index: 1.568
• CAS DataBase Reference: ethyl 6,7,8-trifluoro-1-[formyl(methyl)amino]-4-oxo-1,4-dihydroquinoline-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 6,7,8-trifluoro-1-[formyl(methyl)amino]-4-oxo-1,4-dihydroquinoline-3-carboxylate(100276-65-1)
• EPA Substance Registry System: ethyl 6,7,8-trifluoro-1-[formyl(methyl)amino]-4-oxo-1,4-dihydroquinoline-3-carboxylate(100276-65-1)

Safety Data

• Hazardous Substances Data: 100276-65-1(Hazardous Substances Data)

Usage

General Description

Ethyl 6,7,8-trifluoro-1-[formyl(methyl)amino]-4-oxo-1,4-dihydroquinoline-3-carboxylate is a complex, synthetic chemical compound. The molecule consists of multiple functional groups including an aldehyde (formyl), an amine (amino), a carboxylic ester (carboxylate), and a heterocyclic ring (quinoline) with several fluorine substitutions. It is characterized by the presence of both carbon and nitrogen in its cyclic structure. It is classified as a quinoline and a carboxylate ester. Exact properties such as its physical state, color, solubility, toxicity, reactivity, and uses depend on its specific molecular structure and should be investigated according to its Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) and Superfund Amendments and Reauthorization Act (SARA) status. Due to its complex structure, it is likely used in specific industrial or pharmaceutical applications.

Upstream product

• 100276-64-0 2-(2,3,4,5-Tetrafluorbenzoyl)-3-(2-formyl-2-methylhydrazino)acrylsaeure-ethylester 
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Downstream Products

• 100276-37-7 6,8-Difluor-1-(methylamino)-7-(4-methyl-1-piperazinyl)-1,4-dihydro-4-oxo-3-chinolincarbonsaeure 
• 158585-86-5 ethyl 6,8-difluoro-1,4-dihydro-1-(N-methylformamido)-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylate 

Relevant articles and documents

Process for the manufacture of a tricyclic compound

A process for preparing a compound of formula (I) or a phamaceutically-acceptable salt thereof, comprising: 1) reacting a compound. of formula (III), in which R is a straight or branched chain alkyl having from one to four carbon atoms, with an alkali metal hydroxide in an aqueous medium at a temperature of about 80° to 120° C. and time of about 20 to 100 hours to form a reaction product; 2) cyclizing the reaction product of step 1) with formic acid and formaldehyde to form a formiate compound; and 3) neutralizing the formiate compound of step 2) with an aqueous base.

Antibacterial 1,7-diamino-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids

Antibacterially effective 1,7-diamino-1,4-dihydro-4-oxo-3-(aza)quinolinecarboxylic acids of the formula STR1 in which A is nitrogen or C--R1, R1 is nitro or halogen, R2 and R3 each independently is C1