127221-89-0

Basic information

• Product Name: (2S)-1-aMino-2-PyrrolidineMethanol
• Synonyms: (2S)-1-aMino-2-PyrrolidineMethanol;(S)-(1-AMinopyrrolidin-2-yl)Methanol;(2S)-1-aMiino-2-PyrrolidineMethanol
• CAS NO: 127221-89-0
• Molecular Formula: C₅H₁₂N₂O
• Molecular Weight: 116.16158
• Mol File: 127221-89-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 205.0±13.0 °C(Predicted)
• Appearance: /
• Density: 1.096±0.06 g/cm3(Predicted)
• PKA: 14.77±0.10(Predicted)
• CAS DataBase Reference: (2S)-1-aMino-2-PyrrolidineMethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-1-aMino-2-PyrrolidineMethanol(127221-89-0)
• EPA Substance Registry System: (2S)-1-aMino-2-PyrrolidineMethanol(127221-89-0)

Safety Data

• Hazardous Substances Data: 127221-89-0(Hazardous Substances Data)

Usage

General Description

(2S)-1-aMino-2-PyrrolidineMethanol is a chemical compound with the molecular formula C5H11NO and a molecular weight of 101.15 g/mol. It is a chiral compound, meaning it exists in two enantiomeric forms: (S)- and (R)-. This chemical is commonly used in organic synthesis, medicinal chemistry, and as a chiral building block for the synthesis of pharmaceuticals and agrochemicals. It is also a versatile intermediate in the production of various pharmaceuticals and agrochemicals. Additionally, (2S)-1-aMino-2-PyrrolidineMethanol has potential applications in the development of new drug candidates and research in the fields of pharmacology and biochemistry. Due to its versatile nature and potential applications in various industries, this compound is of significant interest to researchers and chemists.

Upstream product

• 7519-36-0 nitrosoproline 
• 58246-54-1 1-Nitroso-2(S)-pyrrolidinemethanol 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 
• 147-85-3 L-proline 

Downstream Products

• 188053-41-0 N-((S)-2-Hydroxymethyl-pyrrolidin-1-yl)-benzamide 
• 874290-48-9 (1-Ethyl-propylidene)-((S)-2-trityloxymethyl-pyrrolidin-1-yl)-amine 
• 182305-80-2 {(S)-1-[(S)-6,7-Dimethoxy-1-(4-methoxy-benzyl)-3,4-dihydro-1H-isoquinolin-2-yl]-pyrrolidin-2-yl}-methanol 

Relevant articles and documents

(S)-(-)-1-Amino-2-(siloxymethyl)pyrrolidines: Novel and Efficient Reagents for Chromatographic Resolution of α-Substituted Aldehydes

A new aldehyde resolution technique based on the chromatographic seperation (preparative h.p.l.c.) of their epimeric (S)-1-amino-2-(siloxymethyl)pyrrolidine (SASP)-hydrazones is described.

A highly enantioselective, moderately anti-selective aldol reaction using a novel hydrazone moiety as stereo director

The use of novel hydrazones as stereo directors with a view to develop a highly enantioselective, anti-diastereoselective aldol addition procedure has been investigated. A number of proline-derived hydrazones were produced and their effectiveness in direc