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139356-39-1

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  • (1R,3R)-1,3-bis((tert-butyldimethyl)silanyloxy)-5-[2-(diphenylphosphinoyl)-ethylidene]cyclohexane

    Cas No: 139356-39-1

  • USD $ 18.0-20.0 / Kilogram

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  • 10000 Metric Ton/Year

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139356-39-1 Usage

Description

(3R-trans)-[2-[3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]cyclohexylidene]ethyl]diphenyl-phosphine Oxide is a complex organic compound characterized by its unique molecular structure. It is a phosphine oxide derivative with a cyclohexylidene group and diphenyl-phosphine oxide as its core structure. The compound is further modified by the presence of a 3,5-bis[[dimethylethyl)dimethylsilyl]oxy] group, which contributes to its specific properties and potential applications.

Uses

Used in Pharmaceutical Industry:
(3R-trans)-[2-[3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]cyclohexylidene]ethyl]diphenyl-phosphine Oxide is used as an intermediate compound in the synthesis of Vitamin D compounds. Its unique structure allows for the development of pharmaceuticals with potential therapeutic applications, particularly in the treatment of various health conditions related to Vitamin D deficiency or imbalance.
Used in Chemical Research:
(3R-trans)-[2-[3,5-Bis[[(1,1-diMethylethyl)diMethylsilyl]oxy]cyclohexylidene]ethyl]diphenyl-phosphine Oxide may also be utilized in chemical research and development, where its specific properties can be explored for potential applications in the creation of new materials, catalysts, or other advanced chemical products. Its unique structure and functional groups make it a valuable candidate for further investigation and potential use in various chemical processes.

Check Digit Verification of cas no

The CAS Registry Mumber 139356-39-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,3,5 and 6 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 139356-39:
(8*1)+(7*3)+(6*9)+(5*3)+(4*5)+(3*6)+(2*3)+(1*9)=151
151 % 10 = 1
So 139356-39-1 is a valid CAS Registry Number.

139356-39-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl-[(1R,3R)-3-[tert-butyl(dimethyl)silyl]oxy-5-(2-diphenylphosphorylethylidene)cyclohexyl]oxy-dimethylsilane

1.2 Other means of identification

Product number -
Other names (1R,3R)-1,3-bis-((tert-butyldimethyl)silanyloxy)-5-[2-(diphenylphosphinoyl)-eth-(Z)-ylidene]-2-methylene-cyclohexane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:139356-39-1 SDS

139356-39-1Relevant articles and documents

Economical Process for Preparation of the 19-nor A Ring of Paricalcitol from (-)-Shikimic Acid

Zhou, Shengfeng,Zhu, Runyu,Hu, Jingwen,Zhang, Lixiong,Lu, Qian,Yu, Xinhong

, p. 1887 - 1891 (2019/08/26)

An economical and efficient means of preparing the 19-nor A ring, a key precursor of the vitamin D receptor (VDR) activator Paricalcitol, is here described. This process begins with commercially available (-)-shikimic acid and was easily scaled up to kilo

A new metabolite of Paricalcitol: stereoselective synthesis of (22Z)-isomer of 1α,25-dihydroxy-19-norvitamin D2

Samala, Ramakrishna,Sharma, Somesh,Basu, Manas K.,Mukkanti,Porstmann, Frank

, p. 1309 - 1312 (2018/03/26)

Stereoselective synthesis of (22Z)-isomer of Paricalcitol, an analog of 1,25-dihydroxyergocalciferol, an active form of vitamin D2 (Ergocalciferol) has been described. The two key critical synthetic steps involved are Julia–Lythgoe's Wittig–Hor

1-DEOXY ANALOGS OF VITAMIN D-RELATED COMPOUNDS

-

Page/Page column 59-60, (2011/08/04)

This present disclosure is directed to novel prodrugs of activated vitamin D3 compounds. The prodrugs can be designed to have one or more beneficial properties, such as selective inhibition of the enzyme CYP24, low calcemic activity, and anti-proliferativ

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