19618-36-1

Basic information

• Product Name: 2-Propenoic acid, 3,3-bis(4-chlorophenyl)-
• CAS NO: 19618-36-1
• Molecular Formula: C15H10Cl2O2
• Molecular Weight: 293.149
• Mol File: 19618-36-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3,3-bis(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3,3-bis(4-chlorophenyl)-(19618-36-1)
• EPA Substance Registry System: 2-Propenoic acid, 3,3-bis(4-chlorophenyl)-(19618-36-1)

Safety Data

• Hazardous Substances Data: 19618-36-1(Hazardous Substances Data)

Upstream product

• 79-37-8 oxalyl dichloride 
• 2642-81-1 1,1-bis(p-chlorophenyl)ethene 
• 408537-45-1 ethyl 3,3-bis(4-chlorophenyl)-3-hydroxypropanoate 
• 101423-67-0 methyl 3,3-bis(4-chlorophenyl)acrylate 
• 637-87-6 1-Chloro-4-iodobenzene 
• 23594-02-7 3,3-bis(4-chlorophenyl)acrylaldehyde 
• 90-98-2 4,4'-Dichlorobenzophenone 
• 19685-58-6 1,1,2-trichloro-3,3-bis-(4-chloro-phenyl)-propene 
• 50-29-3 p,p'-DDT 
• 408319-17-5 3,3-bis-(4-chloro-phenyl)-3-hydroxy-propionic acid 
• 109846-00-6 3,3,3-trichloro-1,1-bis-(4-chloro-phenyl)-propene 
• 95269-22-0 ethyl 3,3-bis(4'-chlorophenyl)prop-2-enoate 
• 100914-24-7 1,1-dichloro-3,3-bis-(4-chloro-phenyl)-allene 
• 23349-12-4 4,4'-(2-bromoethene-1,1-diyl)bis(chlorobenzene) 

Downstream Products

• 19618-31-6 4-[3,3-bis-(4-chloro-phenyl)-acryloyl]-morpholine 
• 69416-94-0 1,1-bis(4-chlorophenyl)-2-iodoethene 
• 119267-74-2 1,2-bis(4-chlorophenyl)-2-oxoethyl acetate 
• 3439-04-1 4,4'-(prop-1-ene-1,1-diyl)bis(chlorobenzene) 
• 1439401-87-2 3,4-bis(4-chlorophenyl)-1-methylquinolin-2(1H)-one 
• 1439401-67-8 3,3-bis(4-chlorophenyl)-N-methyl-N-phenylacrylamide 
• 1437756-74-5 7-chloro-4-(4-chlorophenyl)-2H-chromen-2-one 
• 1227857-55-7 N-tosyl-3,3-bis(4-chlorophenyl)acrylamide 
• 133261-86-6 1-[3,3-Bis(4-chlorophenyl)acryloyl]-4-(3,4,5-trimethoxybenzoyl)piperazine 
• 3547-04-4 1,1-bis(4-chlorophenyl)ethane 
• 2540-35-4 3,3-bis-(4-chloro-phenyl)-propionic acid 
• 19618-32-7 3.3-Bis-(4-chlor-phenyl)-acrylsaeure-diaethylamid 
• 17656-28-9 3.3-Bis-(4-chlor-phenyl)-acrylsaeure-isopropylamid 
• 17656-27-8 3,3-bis(4-chlorophenyl)-N,N-dimethylacrylamide 

Relevant articles and documents

Synthesis of seven-membered lactones by regioselective and stereoselective iodolactonization of electron-deficient olefins

A regio- A nd stereoselective iodolactonization of internal electron-deficient olefinic acids has been reported, which provides a straightforward access to a series of multi-functionalized seven-membered lactones containing two consecutive chiral centers. The ester substituents on the olefins played a key role in achieving high regioselectivity. This result was proved through experiments and DFT calculations.

A Weinreb Amide Based Building Block for Convenient Access to β,β-Diarylacroleins: Synthesis of 3-Arylindanones

Towards the synthesis of symmetrical and unsymmetrical β,β-diarylacroleins for assembling diarylmethine fragments present in biologically important molecules, we have developed a new Weinreb amide (WA) based building block, derived from propiolic acid. The WA functionality present in this compound allowed the sequential addition of various arylmagnesium bromide reagents in a controlled manner. The developed methodology for the access to β,β-diarylacroleins has been utilised for the synthesis of biologically important 3-arylindanone molecules. Synthesis of both symmetrical and unsymmetrical β,β-diarylacrolein and diarylmethine fragments, have been achieved via easily accessible and hitherto unknown Weinreb Amide (WA) based building block 11. The WA functionality allowed the sequential addition of nucleophiles such as arylmagnesium bromide in a controlled manner, which has enabled the synthesis of an important 3-arylindanone molecule.

Palladium-catalyzed intramolecular amidation of C(sp2)-H bonds: Synthesis of 4-aryl-2-quinolinones

Figure presented A catalytic synthetic approach for the synthesis of 2-quinolinone compounds through a Pd-catalyzed C(sp2)-H functionalization/intramolecular amidation sequence is described. The cyclization process efficiently proceeds in the p