2106-04-9 Usage
Description
3-Chloro-2-fluoroaniline is a dihalo-substituted aniline, characterized by its clear light beige liquid appearance. It possesses unique chemical properties, with an enthalpy of vaporization at boiling point (487.15K) of 42.561kjoule/mol, making it a compound of interest in various chemical and pharmaceutical applications.
Uses
Used in Chemical Synthesis:
3-Chloro-2-fluoroaniline is used as a key intermediate in the synthesis of various organic compounds. Its unique dihalo-substituted structure allows for the creation of a range of products with different functional groups and properties.
Used in Pharmaceutical Industry:
3-Chloro-2-fluoroaniline is used as a building block for the development of pharmaceutical compounds. It is specifically utilized in the preparation of 2-chloro-3-fluorobromobenzene and 4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate, which are important intermediates in the synthesis of potential therapeutic agents.
These applications highlight the versatility of 3-Chloro-2-fluoroaniline in both the chemical and pharmaceutical industries, where its unique properties and reactivity contribute to the development of new and innovative products.
Check Digit Verification of cas no
The CAS Registry Mumber 2106-04-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,1,0 and 6 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2106-04:
(6*2)+(5*1)+(4*0)+(3*6)+(2*0)+(1*4)=39
39 % 10 = 9
So 2106-04-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H5ClFN/c7-4-2-1-3-5(9)6(4)8/h1-3H,9H2
2106-04-9Relevant articles and documents
Method for preparing halogenated aniline from halogenated nitrobenzene through catalytic hydrogenation
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Paragraph 0051-0053, (2017/07/22)
The invention discloses a method for preparing halogenated aniline from halogenated nitrobenzene through catalytic hydrogenation. The method comprises the following steps: in a reaction kettle, performing liquid phase catalytic hydrogenation reaction to halogenated nitrobenzene under the action of a sulfur-doped carbon material loaded noble metal catalyst, to obtain halogenated aniline shown in the formula (II), wherein the loading quantity of noble metal in the sulfur-doped carbon material loaded noble metal catalyst is 0.1-5wt%. In the method, the catalyst has good stability, the hydrogenation halogen removal side effect can be effectively inhibited under the condition of having no added halogen removal inhibitor, and the product selectivity is high.