211246-27-4

Basic information

• Product Name: 8-((1R,4S)-bicyclo[2.2.1]heptan-2-yl)-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one
• Synonyms: 8-((1R,4S)-bicyclo[2.2.1]heptan-2-yl)-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one
• CAS NO: 211246-27-4
• Molecular Formula: C15H17N3OS
• Molecular Weight: 287.37998
• Mol File: 211246-27-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-((1R,4S)-bicyclo[2.2.1]heptan-2-yl)-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8-((1R,4S)-bicyclo[2.2.1]heptan-2-yl)-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one(211246-27-4)
• EPA Substance Registry System: 8-((1R,4S)-bicyclo[2.2.1]heptan-2-yl)-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one(211246-27-4)

Safety Data

• Hazardous Substances Data: 211246-27-4(Hazardous Substances Data)

Upstream product

• 120497-57-6 2-iodobicyclo[2.2.1]heptane 
• 211244-81-4 2-methanesulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one 
• 770-31-0 4-amino-2-(methylthio)pyrimidine-5-carbaldehyde 
• 588-36-3 (4-amino-2-(methylthio)pyrimidin-5-yl)methanol 
• 5909-24-0 4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester 
• 776-53-4 ethyl 4-amino-2-methylmercaptopyrimidine-5-carboxylate 
• 141-78-6 ethyl acetate 

Relevant articles and documents

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Heterocyclic compounds as CDK4 or CDK6 or other CDK inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.

Pyrido[2,3-D]pyrimidines and 4-aminopyrimidines as inhibitors of cellular proliferation

This invention provides pyridopyrimidines and 4-aminopyrimidines that are useful for treating cell proliferative disorders, such as cancer and restenosis. We have now discovered a group of 7,8-dihydro-2-(amino and thio)pyrido[2,3-d]pyrimidines and 2,4-dia