770-31-0 Usage
Description
4-AMINO-2-METHYLTHIO-PYRIMIDINE-5-CARBALDEHYDE is an organic compound with the molecular formula C6H7N3S. It is a key intermediate in the synthesis of various biologically active molecules, particularly those with potential applications in the pharmaceutical industry. Its chemical structure features a pyrimidine core with an amino group at the 4-position, a methylthio group at the 2-position, and a formyl group at the 5-position, which allows for further functionalization and the development of novel therapeutic agents.
Uses
Used in Pharmaceutical Industry:
4-AMINO-2-METHYLTHIO-PYRIMIDINE-5-CARBALDEHYDE is used as a key intermediate for the synthesis of pyridopyrimidines and naphthyridines. These compounds have been identified as potential inhibitors of Akt kinase, a protein that plays a crucial role in cell survival and growth. Inhibition of Akt kinase has been shown to have therapeutic benefits in the treatment of various types of cancer.
The development of pyridopyrimidines and naphthyridines as Akt kinase inhibitors is based on their ability to disrupt the signaling pathways that promote cancer cell proliferation and survival. By targeting this specific enzyme, these compounds can potentially halt the progression of cancer and offer a new avenue for cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 770-31-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,7 and 0 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 770-31:
(5*7)+(4*7)+(3*0)+(2*3)+(1*1)=70
70 % 10 = 0
So 770-31-0 is a valid CAS Registry Number.
770-31-0Relevant articles and documents
SALT FORM AND CRYSTAL FORM OF NOVEL AZATRICYCLIC COMPOUND AND USE THEREOF
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, (2021/11/05)
A maleate, mesylate, benzene sulfonate, hydrochloride, phosphate, L-tartrate, L-malate, citrate, and fumarate of a compound represented by structural formula I, various crystal forms of each salt form, and a preparation method and application thereof.
Pyrido[2,3-d]pyrimidin-7(8H)-one derivatives and Composition for skin whitening and Pharmaceutical composition for use in preventing or treating disorders of Melanin Hyperpigmentation containing the same as an active ingredient
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, (2020/11/03)
The present invention relates to a pyrido[2,3-d]pyrimidin-7(8H)-one derivative, and to a composition for skin whitening comprising the same as an active ingredient. Since the derivative exhibits an effect of inhibiting the production of melanin even when
PROTEIN KINASE INHIBITORS AND USES THEREOF FOR THE TREATMENT OF DISEASES AND CONDITIONS
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, (2020/11/30)
Identified compounds demonstrate protein kinase inhibitory activity. More specifically, the compounds are demonstrated to inhibit receptor interacting kinase 2 (RIPK2) and/or Activin-like kinase 2 (ALK2) and/or receptor interacting kinase 3 (RIPK3). Compounds that are either dual RIPK2/ALK2 inhibitors or that preferentially inhibit RIPK2 or ALK2 or RIPK3 could provide therapeutic benefit. Compounds that function as RIPK3 inhibitors provide therapeutic benefit in the treatment of inflammatory and degenerative conditions.
