211244-82-5

Basic information

• Product Name: 8-Ethyl-2-methanethio-8H-pyrido[2,3-d]pyrimidin-7-one
• Synonyms: 8-Ethyl-2-methanethio-8H-pyrido[2,3-d]pyrimidin-7-one
• CAS NO: 211244-82-5
• Molecular Formula: C10H11N3OS
• Molecular Weight: 221.27884
• Mol File: 211244-82-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-Ethyl-2-methanethio-8H-pyrido[2,3-d]pyrimidin-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Ethyl-2-methanethio-8H-pyrido[2,3-d]pyrimidin-7-one(211244-82-5)
• EPA Substance Registry System: 8-Ethyl-2-methanethio-8H-pyrido[2,3-d]pyrimidin-7-one(211244-82-5)

Safety Data

• Hazardous Substances Data: 211244-82-5(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic aromatic organic compound

Structure

Contains a pyridine ring fused to a pyrimidine ring

Known for

Potential biological activity

Studied for

Potential pharmacological properties

Common use

Building block in the synthesis of pharmaceutical and medicinal compounds

Value in research

Unique structure and properties make it a valuable tool in medicinal and organic chemistry research

Upstream product

• 75-03-6 ethyl iodide 
• 211244-81-4 2-methanesulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one 
• 770-31-0 4-amino-2-(methylthio)pyrimidine-5-carbaldehyde 
• 588-36-3 (4-amino-2-(methylthio)pyrimidin-5-yl)methanol 
• 5909-24-0 4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester 
• 776-53-4 ethyl 4-amino-2-methylmercaptopyrimidine-5-carboxylate 
• 185040-34-0 (4-ethylamino-2-methanesulfanyl-pyrimidin-5-yl)-methanol 
• 185040-35-1 4-ethylamino-2-methylthiopyrimidine-5-carboxaldehyde 
• 185040-33-9 4-ethylamino-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester 
• 211244-85-8 ethyl 3-(4-ethylamino-2-methanesulfanyl-pyrimidin-5-yl)acrylate 
• 6674-22-2 1,8-diazabicyclo[5.4.0]undec-7-ene 

Downstream Products

• 211245-16-8 8-ethyl-2-(4-hydroxyphenylamino)-8H-pyrido[2,3-d]pyrimidin-7-one 
• 211245-12-4 8-ethyl-2-(4-methoxyphenylamino)-8H-pyrido[2,3-d]pyrimidin-7-one 
• 211245-14-6 8-Ethyl-2-[4-(4-methylpiperazin-1-yl)-phenylamino]-8H-pyrido[2,3-d]-pyrimidin-7-one 

Relevant articles and documents

GEM-DISUBSTITUTED HETEROCYCLIC COMPOUNDS AND THEIR USE AS IDH INHIBITORS

The present invention relates to certain gem-disubstituted heterocyclic compounds, which modulate the activity of Isocitrate Dehydrogenase (IDH). The compounds of this invention are therefore useful in treating diseases caused by mutated IDH1 and/or mutat

Pyridopyrimidinone derivatives for treatment of neurodegenerative disease

This invention provides pyridopyrimidines and 4-aminopyrimidines that are useful for treating cell proliferatives disorders, such as cancer and restenosis. We have now discovered a group of 7,8-dihydro-2 (amino and thio)pyrido[2,3-d]pyrimidines and 2,4-di

Pyrido[2,3-d]pyrimidin-7-one inhibitors of cyclin-dependent kinases

The identification of 8-ethyl-2-phenylamino-8H-pyrido [2,3-d]pyrimidin-7-one (1) as an inhibitor of Cdk4 led to the initiation of a program to evaluate related pyrido [2,3-d]pyrimidin-7-ones for inhibition of cyclin-dependent kinases (Cdks). Analysis of m