23783-42-8 Usage
Description
TETRAETHYLENEGLYCOL MONOMETHYL ETHER, also known as m-PEG4-alcohol, is a monofunctional polyethylene glycol (PEG) derivative featuring a hydroxyl group. This hydroxyl group allows for further derivatization or substitution with other reactive functional groups, making it a versatile compound in various chemical and pharmaceutical applications. The hydrophilic PEG spacer enhances solubility in aqueous media, and it is characterized as a clear, colorless to very slightly yellow liquid.
Uses
Used in Chemical Synthesis:
TETRAETHYLENEGLYCOL MONOMETHYL ETHER is used as a building block for the synthesis of various chemical compounds, leveraging its reactive hydroxyl group and hydrophilic PEG spacer.
Used in Polymer Science:
TETRAETHYLENEGLYCOL MONOMETHYL ETHER is used as a monofunctional PEG linker in polymer science, enabling the creation of polymers with specific properties and functionalities by attaching it to other monomers or polymer chains.
Used in Pharmaceutical Applications:
TETRAETHYLENEGLYCOL MONOMETHYL ETHER is used as a pharmaceutical intermediate for the development of drugs with improved solubility and bioavailability, taking advantage of its hydrophilic nature and ability to form derivatives.
Used in Drug Delivery Systems:
In the pharmaceutical industry, TETRAETHYLENEGLYCOL MONOMETHYL ETHER is used as a component in drug delivery systems to enhance the solubility, stability, and targeted delivery of therapeutic agents.
Used in Cosmetics and Personal Care:
TETRAETHYLENEGLYCOL MONOMETHYL ETHER is used as an ingredient in cosmetics and personal care products for its solubilizing properties, helping to improve the formulation's overall performance and efficacy.
Used in Environmental Applications:
In environmental science, TETRAETHYLENEGLYCOL MONOMETHYL ETHER is used for the development of materials with specific properties, such as degradability or water solubility, to address various ecological challenges.
Check Digit Verification of cas no
The CAS Registry Mumber 23783-42-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,7,8 and 3 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 23783-42:
(7*2)+(6*3)+(5*7)+(4*8)+(3*3)+(2*4)+(1*2)=118
118 % 10 = 8
So 23783-42-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H20O5/c1-11-4-5-13-8-9-14-7-6-12-3-2-10/h10H,2-9H2,1H3
23783-42-8Relevant articles and documents
Detecting a transition-metal ammine at tailored surfaces
Iqbal, Sayeedha,Kremer, Felix J.B.,Ringsdorf, Helmut,Steinbeck, Martin,Stoddart, J. Fraser,Shen, Jie,Tinker, Nigel D.
, p. 1147 - 1154 (1997)
The fabrication of surfaces by forming Langmuir films, which incorporate amphiphiles containing hydrophilic 18-crown-6 (18C6) derivatives, at a gas/water interface is described. These Langmuir films can be transferred to a hydrophobised quartz crystal microbalance (QCM), using the Langmuir-Blodgett technique. The QCM response has been measured in aqueous solution as a function of the concentration of the transition metal complex [Co(NH3)6]Cl3 which was injected into a vial in which the film-coated QCM had been immersed. By comparing various surfaces covered with hydrophilic polyether and hydroxy functions and hydrophobic methyl groups, and by varying the composition of the films so as to increase the separation between the 18C6 macrocycles, it has been demonstrated that surfaces can be tailored that will enhance the binding of the [Co(NH3)6]3+ trications.
Monodisperse polyethylene glycol “brushes” with enhanced lipophilicity, and thermo and plasma stability
Li, Yu,Wang, Xuemeng,Chen, Yongping,Yang, Zhigang,Jiang, Zhong-Xing
supporting information, p. 1895 - 1898 (2019/05/02)
A convenient strategy was developed for highly branched and multifunctionalized peptidic monodisperse polyethylene glycol “brushes”, which exhibit remarkable physicochemical and biological properties and potential as versatile biomaterials.
INHIBITORS OF HEPATITIS C VIRUS POLYMERASE
-
, (2016/10/11)
The present invention provides, among other things, compounds represented by the general Formula I: (I) and pharmaceutically acceptable salts thereof, wherein L and A (and further substituents) are as defined in classes and subclasses herein and compositions (e.g., pharmaceutical compositions) comprising such compounds, which compounds are useful as inhibitors of hepatitis C virus polymerase, and thus are useful, for example, as medicaments for the treatment of HCV infection.
