253443-43-5

Basic information

• Product Name: 5-(chloromethyl)-3-(4-fluorophenyl)-4,5-dihydroisoxazole
• Synonyms: 5-(chloromethyl)-3-(4-fluorophenyl)-4,5-dihydroisoxazole
• CAS NO: 253443-43-5
• Molecular Weight: 213.639
• Mol File: 253443-43-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-(chloromethyl)-3-(4-fluorophenyl)-4,5-dihydroisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(chloromethyl)-3-(4-fluorophenyl)-4,5-dihydroisoxazole(253443-43-5)
• EPA Substance Registry System: 5-(chloromethyl)-3-(4-fluorophenyl)-4,5-dihydroisoxazole(253443-43-5)

Safety Data

• Hazardous Substances Data: 253443-43-5(Hazardous Substances Data)

Upstream product

• 904672-47-5 1-(4-fluorophenyl)but-3-en-1-one oxime 
• 459-57-4 4-fluorobenzaldehyde 
• 86718-78-7 1-(4-fluorophenyl)-3-buten-1-ol 
• 61668-02-8 1-(4-fluorophenyl)but-3-en-1-one 
• 588-95-4 syn-4-fluorobenzaldoxime 
• 107-05-1 3-chloroprop-1-ene 

Relevant articles and documents

General 5-Halomethyl Isoxazoline Synthesis Enabled by Copper-Catalyzed Oxyhalogenation of Alkenes

A general and efficient oxyhalogenation of unsaturated ketoximes has been achieved through copper catalysis with diethyl bromomalonate, N-chlorosuccinimide, and N-iodosuccinimide, yielding 5-chloromethyl, 5-bromomethyl, and 5-iodomethyl isoxazolines in go

Oxime-mediated oxychlorination and oxybromination of unactivated olefins

An oxime-mediated oxychlorination and oxybromination of unactivated olefins relying on palladium catalysis has been developed. A wide range of chlorinated and brominated isoxazolines has been synthesized in moderate to good yields. To demonstrate the value of the method, the brominated isoxazoline has been further converted to other useful synthetic feedstock.