2852-91-7

Basic information

• Product Name: (2-CARBOXYPHENYL)ACETONE
• Synonyms: 2-(2-OXOPROPYL)BENZOIC ACID;(2-CARBOXYPHENYL)ACETONE
• CAS NO: 2852-91-7
• Molecular Formula: C₁₀H₁₀O₃
• Molecular Weight: 178.18
• Mol File: 2852-91-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 319.925°C at 760 mmHg
• Flash Point: 161.5°C
• Appearance: /
• Density: 1.201g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.552
• CAS DataBase Reference: (2-CARBOXYPHENYL)ACETONE(CAS DataBase Reference)
• NIST Chemistry Reference: (2-CARBOXYPHENYL)ACETONE(2852-91-7)
• EPA Substance Registry System: (2-CARBOXYPHENYL)ACETONE(2852-91-7)

Safety Data

• Hazardous Substances Data: 2852-91-7(Hazardous Substances Data)

Usage

Description

(2-CARBOXYPHENYL)ACETONE, also known as 2-carboxy-2-phenylacetone, is a chemical compound with the molecular formula C10H10O3. It is a white to off-white crystalline powder that is primarily used as an intermediate in the pharmaceutical industry for the synthesis of various drugs.

Uses

Used in Pharmaceutical Industry:
(2-CARBOXYPHENYL)ACETONE is used as an intermediate for the synthesis of various drugs, contributing to the development of new medications and therapies.
Used in Organic Compound Production:
(2-CARBOXYPHENYL)ACETONE is used as a precursor for the production of other organic compounds, such as dyes and fragrances, enhancing the range of products available in these industries.
Used in Synthesis of Complex Organic Molecules:
(2-CARBOXYPHENYL)ACETONE is used as a versatile reagent in the synthesis of complex organic molecules, enabling the creation of intricate chemical structures for various applications.
Safety Precautions:
It is important to handle (2-CARBOXYPHENYL)ACETONE with care, as it may be harmful if swallowed, inhaled, or in contact with skin and eyes. Proper safety measures should be taken during its use and storage to minimize potential risks.

InChI:InChI=1/C10H10O3/c1-7(11)6-8-4-2-3-5-9(8)10(12)13/h2-5H,6H2,1H3,(H,12,13)

Upstream product

• 29539-21-7 3-methylisocoumarin 
• 17496-14-9 2,3-dihydro-2-methyl-1H-inden-1-one 
• 52962-26-2 3-(o-carboxyphenyl)pentane-2,4-dione 
• 75724-96-8 3-(chloroacetyl)phthalide 
• 115912-93-1 2-(2-nitropropyl)benzoic acid 
• 67-64-1 acetone 
• 88-65-3 2-bromobenzoic-acid 
• 7115-18-6 methyl 2-(2-oxopropyl)benzoate 
• 88-67-5 2-Iodobenzoic acid 
• 123-54-6 acetylacetone 
• 16859-59-9 3-hydroxy-1(3H)-isobenzofuranone 
• 79017-08-6 3-(1-nitroethyl)-1(3H)-isobenzofuranone 
• 528-46-1 phthalonic acid 
• 129881-51-2 acid chloride of 1-oxo-1,3-dihydroisobenzofuran-3-carboxylic acid 

Downstream Products

• 7115-18-6 methyl 2-(2-oxopropyl)benzoate 
• 93361-24-1 2-(3-methyl-1-oxoisoquinolin-2(1H)-yl)benzonitrile 
• 93361-26-3 2-(2-carbamoylphenyl)-3-methylisocarbostyril 
• 93361-25-2 methyl 2-(3-methyl-1-oxoisoquinolin-2(1H)-yl)benzoate 
• 7114-80-9 3-methylisoquinolone 
• 862311-07-7 2-(4-methoxyphenyl)-3-methylisoquinolin-1(2H)-one 
• 185738-14-1 2-(1-(4-Bromobenzyl)-5-methoxy-2-methyl-1 H-indol-3-yl) benzoic acid 
• 1259022-97-3 (E)-2-[4-(3,4-dimethoxyphenyl)-2-oxobut-3-enyl]benzoic acid 
• 7114-80-9 3-methylisoquinolin-1-ol 
• 73013-47-5 2-(2-Oxo-propyl)-benzoic acid ethyl ester 

Relevant articles and documents

Synthesis and X-ray crystal structure analysis of 1,4-epoxy-4-methyl-1H,4H- 2,3-benzodioxepin

Ozonolysis of 2-methyl-1H-indene (1) afforded the stable secondary ozonide 1,4-epoxy-4-methyl-1H,4H-2,3-benzodioxepin (2). This compound crystallizes in two polymorphic forms, depending on the solvent used. The monoclinic form 2a containing two symmetry-independent molecules (enantiomers) is obtained by crystallization from dichloromethane. In contrast, the orthorhombic modification 2b is obtained from ethyl acetate solution and crystallizes as a conglomerate of enantiomerically pure single crystals. Additionally, the ring-opened product 2-(2-oxopropyl)benzoic acid (3) was obtained and investigated by X-ray crystal structure analysis.

Selective C-C Bond Cleavage of Cycloalkanones by NaNO2/HCl

A novel selective fragmentation of cycloalkanones by NaNO2/HCl has been established. The C-C bond cleavage reaction proceeds smoothly under mild conditions, selectively affording versatile keto acids or oxime acids. The methodology can streamline the synthesis of valuable chiral molecules and isocoumarins from readily available feedstocks.

Aqueous organotin chemistry: Part 3 - Triphenyltin hydride and di-n-butyltin dichloride mediated nucleophilic substitution of 2-iodobenzoates in water

This paper demonstrates the nucleophilic displacement of the iodine in 2-iodobenzoates mediated by triphenyltin hydride and di-n-butyltin dichloride in water.