3005-60-5

Basic information

• Product Name: methyl N-benzoylleucinate
• CAS NO: 3005-60-5
• Molecular Formula: C₁₄H₁₉NO₃
• Molecular Weight: 249.3056
• Mol File: 3005-60-5.mol
• Article Data: 25

Chemical Properties

• Boiling Point: 409.8°C at 760 mmHg
• Flash Point: 201.6°C
• Density: 1.069g/cm³
• Vapor Pressure: 6.33E-07mmHg at 25°C
• Refractive Index: 1.507
• CAS DataBase Reference: methyl N-benzoylleucinate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl N-benzoylleucinate(3005-60-5)
• EPA Substance Registry System: methyl N-benzoylleucinate(3005-60-5)

Safety Data

• Hazardous Substances Data: 3005-60-5(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 1466-83-7 N-benzoyl-L-leucine 
• 2666-93-5 (S)-Leu-OMe 
• 98-88-4 benzoyl chloride 
• 91083-90-8 methyl N-nitrosohippurate 
• 67-56-1 methanol 
• 25163-98-8 4-isobutyl-2-phenyloxazol-5(4H)-one 
• 7517-19-3 methyl (L)-leucinate hydrochloride 
• 51021-87-5 N-benzyloxycarbonyl-L-leucine methyl ester 
• 952524-02-6 (S)-1-benzoyl-2-(α-acetoxyethyl)benzimidazole 
• 18869-43-7 DL-leucine methyl ester 
• 1205-08-9 methyl hippurate 
• 61-90-5 L-leucine 
• 100-52-7 benzaldehyde 

Downstream Products

• 1466-83-7 N-benzoyl-L-leucine 
• 17350-65-1 (S)-N-(1-hydrazinyl-4-methyl-1-oxopentan-2-yl)benzamide 
• 100723-52-2 N-Nitroso-N-benzoyl-L-leucin-methylester 
• 76368-10-0 N-(1-hydroxy-1-methylethyl)isopentylbenzamide 
• 10249-88-4 (S)-4-methyl-[(phenylmethyl)amino]pentan-1-ol 
• 880160-22-5 (S)-N-(6-methylhepta-1,2-dien-4-yl)benzamide 
• 121225-27-2 N-benzoyl-L-leucyl-L-proline methyl ester 
• 658053-34-0 N-benzoyl-D,L-leucyl-L-proline 
• 502761-27-5 1-tert-butyloxycarbonylamino-3-[(N-benzoyl)-L-leucyl-L-prolyl-amino]propane 
• 502761-28-6 RA-1004 
• 4515-17-7 N,N'-isopentylidene-bis-benzamide 

Relevant articles and documents

Expedient access to pre-organized α-helix mimetics based on an isocinchomeronic acid core

A previously reported terephthalamide-based α-helix mimetic was modified by introducing a pyridine nitrogen and converting a tertiary amide to a secondary amide, which afforded a second intramolecular hydrogen bond to further influence the projection of t

Amidation of Aldehydes with Amines under Mild Conditions Using Metal-Organic Framework Derived NiO@Ni Mott-Schottky Catalyst

Here we report a facile method for the synthesis of nickel oxide-nickel (NiO@Ni) Mott-Schottky catalyst employing metal-organic framework (MOF) as the precursor. A direct amidation protocol of aldehydes with amines has been optimized under mild conditions using NiO@Ni Mott-Schottky catalyst and it shows far better catalytic activity than the NiO?Ni nanoparticles prepared from simple Ni2+ salt under similar reaction conditions. The heterogeneous catalyst is robust, recyclable and efficient to provide comparable yield to costly ligand-based homogeneous Ni catalysts. The scope of the reaction protocol has been explored with variably substituted substrates. The reaction initiates by homolytic cleavage of peroxide and proceeds through radical mechanism.

Synthesis of Hydrazones from Amino Acids and their Antimicrobial and Cytotoxic Activities

Hydrazones 6a–6n were synthesized from different amino acids with various aldehydes under reflux in methanol/ethanol. The structures of synthesized compounds were ascertained by elemental analysis and spectroscopic techniques. A comparative study of the antimicrobial activity and cytotoxicity was carried out of the N-protected amino acids, their esters, hydrazides, and the respective hydrazones, providing good results in cytotoxicity studies.