360075-35-0

Basic information

• Product Name: C₅₀H₅₃NO₁₄
• Synonyms: C₅₀H₅₃NO₁₄
• CAS NO: 360075-35-0
• Molecular Weight: 891.969
• Mol File: 360075-35-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₅₀H₅₃NO₁₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₀H₅₃NO₁₄(360075-35-0)
• EPA Substance Registry System: C₅₀H₅₃NO₁₄(360075-35-0)

Safety Data

• Hazardous Substances Data: 360075-35-0(Hazardous Substances Data)

Upstream product

• 860782-65-6 3'-dephenyl-3'-(m-vinylphenyl)-4-deacetyl-4-(pent-4-enoyl)-7-O-triethylsilyl-2'-O-triisopropylsilylpaclitaxel 
• 360075-44-1 C₅₂H₈₈O₁₀Si₄ 
• 360075-40-7 4-deacetyl-4-(pent-4-enoyl)-7-O-triethylsilylbaccatin III 
• 360075-46-3 C₃₄H₄₂O₁₁ 
• 360075-45-2 C₃₂H₄₀O₁₀ 
• 360075-43-0 (3R,4S)-1-benzoyl-3-triisopropylsilyloxy-4-(m-vinylphenyl)azetidin-2-one 
• 286933-08-2 (3R,4S)-1-(4-methoxyphenyl)-3-triisopropylsiloxy-4-(3-ethenylphenyl)azetidin-2-one 
• 930785-88-9 (3R,4S)-3-Triisopropylsilanyloxy-4-(3-vinyl-phenyl)-azetidin-2-one 
• 19955-99-8 3-ethenylbenzaldehyde 
• 930785-83-4 acetic acid 1-(4-methoxy-phenyl)-2-oxo-4-(3-vinyl-phenyl)-azetidin-3-yl ester 
• 941672-16-8 3-hydroxy-1-(4-methoxy-phenyl)-4-(3-vinyl-phenyl)-azetidin-2-one 
• 860782-73-6 C₆₅H₈₇NO₁₄Si₂ 

Relevant articles and documents

Evaluation of the tubulin-bound paclitaxel conformation: Synthesis, biology, and SAR studies of C-4 to C-3′ bridged paclitaxel analogues

The important anticancer drug paclitaxel binds to the β-subunit of the ββ-tubulin dimer in the microtubule in a stoichiometric ratio, promoting microtubule polymerization and stability. The conformation of microtubule-bound drug has been the subject of in

Synthesis and biological evaluation of novel macrocyclic paclitaxel analogues

matrix presented This work describes the synthesis of two novel macrocyclic taxoid constructs by ring-closing olefin metathesis (RCM) and their biological evaluation. Computational studies examine conformational profiles of 1 and 2 for their fit to the β-