860782-65-6

Basic information

• Product Name: 3'-dephenyl-3'-(m-vinylphenyl)-4-deacetyl-4-(pent-4-enoyl)-7-O-triethylsilyl-2'-O-triisopropylsilylpaclitaxel
• Synonyms: 3'-dephenyl-3'-(m-vinylphenyl)-4-deacetyl-4-(pent-4-enoyl)-7-O-triethylsilyl-2'-O-triisopropylsilylpaclitaxel
• CAS NO: 860782-65-6
• Molecular Weight: 1190.63
• Mol File: 860782-65-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3'-dephenyl-3'-(m-vinylphenyl)-4-deacetyl-4-(pent-4-enoyl)-7-O-triethylsilyl-2'-O-triisopropylsilylpaclitaxel(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-dephenyl-3'-(m-vinylphenyl)-4-deacetyl-4-(pent-4-enoyl)-7-O-triethylsilyl-2'-O-triisopropylsilylpaclitaxel(860782-65-6)
• EPA Substance Registry System: 3'-dephenyl-3'-(m-vinylphenyl)-4-deacetyl-4-(pent-4-enoyl)-7-O-triethylsilyl-2'-O-triisopropylsilylpaclitaxel(860782-65-6)

Safety Data

• Hazardous Substances Data: 860782-65-6(Hazardous Substances Data)

Upstream product

• 360075-44-1 C₅₂H₈₈O₁₀Si₄ 
• 360075-46-3 C₃₄H₄₂O₁₁ 
• 360075-45-2 C₃₂H₄₀O₁₀ 
• 286933-08-2 (3R,4S)-1-(4-methoxyphenyl)-3-triisopropylsiloxy-4-(3-ethenylphenyl)azetidin-2-one 
• 930785-88-9 (3R,4S)-3-Triisopropylsilanyloxy-4-(3-vinyl-phenyl)-azetidin-2-one 
• 19955-99-8 3-ethenylbenzaldehyde 
• 39716-58-0 pent-4-enoyl chloride 
• 13154-24-0 triisopropylsilyl chloride 
• 994-30-9 triethylsilyl chloride 
• 930785-83-4 acetic acid 1-(4-methoxy-phenyl)-2-oxo-4-(3-vinyl-phenyl)-azetidin-3-yl ester 
• 941672-16-8 3-hydroxy-1-(4-methoxy-phenyl)-4-(3-vinyl-phenyl)-azetidin-2-one 
• 360075-43-0 (3R,4S)-1-benzoyl-3-triisopropylsilyloxy-4-(m-vinylphenyl)azetidin-2-one 
• 360075-40-7 4-deacetyl-4-(pent-4-enoyl)-7-O-triethylsilylbaccatin III 

Downstream Products

• 360075-35-0 C₅₀H₅₃NO₁₄ 
• 860782-73-6 C₆₅H₈₇NO₁₄Si₂ 

Relevant articles and documents

Evaluation of the tubulin-bound paclitaxel conformation: Synthesis, biology, and SAR studies of C-4 to C-3′ bridged paclitaxel analogues

The important anticancer drug paclitaxel binds to the β-subunit of the ββ-tubulin dimer in the microtubule in a stoichiometric ratio, promoting microtubule polymerization and stability. The conformation of microtubule-bound drug has been the subject of in