402567-86-6 Usage
Description
ETHYL 2,4-DIPHENYL-1,3-THIAZOLE-5-CARBOXYLATE is a chemical compound with the molecular formula C19H17NO2S. It is a thiazole derivative with a carboxylate functional group and ethyl ester substituent. ETHYL 2,4-DIPHENYL-1,3-THIAZOLE-5-CARBOXYLATE is commonly used in medicinal chemistry and pharmaceutical research as a building block for the synthesis of various biologically active molecules. It exhibits potential anti-inflammatory and antimicrobial properties, making it an important intermediate in the development of new drugs. Additionally, it has been reported to have potential applications in the field of organic electronics and materials science due to its unique electronic and optical properties.
Uses
Used in Pharmaceutical Industry:
ETHYL 2,4-DIPHENYL-1,3-THIAZOLE-5-CARBOXYLATE is used as a building block for the synthesis of biologically active molecules for various therapeutic applications. Its potential anti-inflammatory and antimicrobial properties make it a valuable intermediate in the development of new drugs.
Used in Organic Electronics:
ETHYL 2,4-DIPHENYL-1,3-THIAZOLE-5-CARBOXYLATE is used in the field of organic electronics due to its unique electronic and optical properties, which can contribute to the development of advanced electronic devices and materials.
Used in Materials Science:
ETHYL 2,4-DIPHENYL-1,3-THIAZOLE-5-CARBOXYLATE is utilized in materials science for its potential applications in creating new materials with enhanced properties, such as improved conductivity or optical characteristics.
Check Digit Verification of cas no
The CAS Registry Mumber 402567-86-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,2,5,6 and 7 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 402567-86:
(8*4)+(7*0)+(6*2)+(5*5)+(4*6)+(3*7)+(2*8)+(1*6)=136
136 % 10 = 6
So 402567-86-6 is a valid CAS Registry Number.
402567-86-6Relevant articles and documents
Highly efficient and green synthesis of 2,4-diphenyl substituted thiazoles
Zhang, Jungan,Li, Peipei,Zeng, Hongyun,Huang, Yu,Hong, Wei
supporting information, p. 735 - 741 (2020/02/11)
2,4-Diphenyl thiazole is an important organic intermediate and its derivatives contain multiple biological properties. In the present study, we reported a new protocol to synthesize 2,4-diphenyl thiazole analogs, which involved the bromination of ethyl benzoylacetates with NBS in the presence of 2-hydroxypropyl-β-cyclodextrin, followed by a direct cyclization with thiobenzamides in water. Compared with the reported method, the current protocol contains less reaction steps, milder reaction conditions, and simpler workup procedure.
Iron-Catalyzed Synthesis of Substituted Thiazoles from Enamines and Elemental Sulfur through C?S Bond Formation
Wu, Mingzhong,Jiang, Yong,An, Zhenyu,Qi, Zhenjie,Yan, Rulong
, p. 4236 - 4240 (2018/09/20)
An atom economical approach for the synthesis of substituted thiazoles starting from enamines and elemental sulfur through the C?H functionalization/C?S bond formation is described. Under the optimized conditions, various substituted enamines reacted smoothly with elemental sulfur and the desired substituted thiazoles were generated in moderate to excellent yields. (Figure presented.).
THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS
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Paragraph 0071; 0072, (2014/09/30)
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.