42712-64-1 Usage
Description
2-AMINO-4-HYDROXYQUINOLINE HYDRATE is an organic compound with the molecular formula C9H8N2O?H2O. It is a derivative of quinoline, featuring an amino group at the 2nd position and a hydroxyl group at the 4th position, along with a water molecule as a hydrate. 2-AMINO-4-HYDROXYQUINOLINE HYDRATE is known for its potential applications in various chemical and pharmaceutical processes due to its unique structure and reactivity.
Uses
Used in Pharmaceutical Industry:
2-AMINO-4-HYDROXYQUINOLINE HYDRATE is used as a key intermediate in the synthesis of various quinazoline and quinazoline derivatives. These derivatives are important for the development of new drugs and pharmaceutical compounds, as they possess a wide range of biological activities, including anti-cancer, anti-inflammatory, and anti-microbial properties.
Used in Chemical Research:
In the field of chemical research, 2-AMINO-4-HYDROXYQUINOLINE HYDRATE serves as a valuable reagent for the preparation of quinazoline-based compounds. These compounds are of significant interest due to their diverse applications in medicinal chemistry, materials science, and other related fields.
Used in Organic Synthesis:
2-AMINO-4-HYDROXYQUINOLINE HYDRATE is also utilized in organic synthesis as a building block for the creation of more complex organic molecules. Its unique functional groups allow for various chemical reactions, enabling the synthesis of a wide array of compounds with potential applications in different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 42712-64-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,7,1 and 2 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 42712-64:
(7*4)+(6*2)+(5*7)+(4*1)+(3*2)+(2*6)+(1*4)=101
101 % 10 = 1
So 42712-64-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H8N2O/c10-9-5-8(12)6-3-1-2-4-7(6)11-9/h1-5H,(H3,10,11,12)
42712-64-1Relevant articles and documents
QUINOLINE-BASED KINASE INHIBITORS
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Page/Page column 105, (2015/11/02)
The present disclosure is generally directed to compounds of formula (I) which can inhibit AAKI (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAKI.
Process for making 2-amino-4-hydroxyquinolines
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, (2008/06/13)
The reaction of isatoic anhydrides with malononitrile in a reaction-inert solvent in the presence of a base to produce 2-amino-3-cyano-4-hydroxy-quinolines and 2-amino-α,α-dicyanoacetophenones which are then hydrolyzed and decarboxylated under acid or base conditions to produce 2-amino-4-hydroxy-quinolines, useful as intermediates for preparation of 1-oxo-1H-6-alkoxy-pyrimido[1,2-a]quinoline-2-carboxylic acids and esters of value as antiallergy agents.
