62705-47-9

Basic information

• Product Name: 2-Quinazolinecarboxylic acid, 6-chloro-4-phenyl-, methyl ester
• Synonyms: 2-Quinazolinecarboxylic acid,6-chloro-4-phenyl-,methyl ester;6-chloro-4-phenyl-quinazoline-2-carboxylic acid methyl ester
• CAS NO: 62705-47-9
• Molecular Formula: C16H11ClN2O2
• Molecular Weight: 298.729
• Mol File: 62705-47-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Quinazolinecarboxylic acid, 6-chloro-4-phenyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Quinazolinecarboxylic acid, 6-chloro-4-phenyl-, methyl ester(62705-47-9)
• EPA Substance Registry System: 2-Quinazolinecarboxylic acid, 6-chloro-4-phenyl-, methyl ester(62705-47-9)

Safety Data

• Hazardous Substances Data: 62705-47-9(Hazardous Substances Data)

Upstream product

• 88190-77-6 6-chloro-3,4-dihydro-4-phenylquinazoline-2-carboxylic acid 
• 719-59-5 5-chloro-2-aminobenzophenone 
• 67-56-1 methanol 
• 5958-08-7 6-chloro-4-phenylquinazoline-2-carboxylic acid 
• 5185-54-6 2-chloro-4-phenyl-6-chloroquinazoline 
• 4797-43-7 6-chloro-4-phenylquinazolin-2-ol 
• 51483-21-7 6-chloro-4-phenylquinazoline-2-carbonitrile 
• 153681-82-4 6-chloro-1,2-dihydro-4-phenylquinazoline-2-carboxylic acid 

Downstream Products

• 30739-34-5 (6-chloro-4-phenylquinazolin-2-yl)methanol 

Relevant articles and documents

4-ARYLQUINAZOLINE DERIVATIVES AS INHIBITORS OF METHIONINE ADENOSYLTRANSFERASE 2A

The invention relates to certain derivatives of 4-arylquinazoline formula (I) which are inhibitors of methionine adenosyltransferase 2A (MAT2A). The invention also relates to pharmaceutical compositions comprising such compounds and methods of treating diseases that can be treated by inhibition of MAT2A such as cancer, including cancers characterized by reduced or no activity of methylthioadenosine phosphorylase (MTAP).