927690-12-8

Basic information

• Product Name: Benzeneethanol, b-(4-chlorophenyl)-b-phenyl-4-(1-pyrrolidinylmethyl)-
• CAS NO: 927690-12-8
• Molecular Formula: C25H26ClNO
• Molecular Weight: 391.941
• Mol File: 927690-12-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzeneethanol, b-(4-chlorophenyl)-b-phenyl-4-(1-pyrrolidinylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanol, b-(4-chlorophenyl)-b-phenyl-4-(1-pyrrolidinylmethyl)-(927690-12-8)
• EPA Substance Registry System: Benzeneethanol, b-(4-chlorophenyl)-b-phenyl-4-(1-pyrrolidinylmethyl)-(927690-12-8)

Safety Data

• Hazardous Substances Data: 927690-12-8(Hazardous Substances Data)

Upstream product

• 91457-11-3 4-bromomethyl-4'-chlorobenzophenone 
• 106-38-7 para-bromotoluene 
• 927690-05-9 (+/-)-(4-chlorophenyl)[4-(pyrrolidin-1-ylmethyl)phenyl]phenylmethanol 
• 742085-16-1 (4-chlorophenyl)[4-(pyrrolidin-1-ylmethyl)phenyl]methanone 
• 927690-16-2 (+/-)-2-(4-chlorophenyl)-2-phenyl-2-{4-[(pyrrolidin-1-yl)methyl]phenyl}acetaldehyde 
• 104-88-1 4-chlorobenzaldehyde 
• 5395-79-9 4'-methyl-4-chlorobenzophenone 

Relevant articles and documents

ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE

Antimalarial agents having a novel pharmacophore of formula (I) are herein described. These polycyclic compounds are able to inhibit chloroquine-sensitive and chloroquine-resistant strains ofPlasmodium falciparum (Pf). Furthermore, the synthesis of these compounds involves few steps from commercial products with low cost of production.Λa présente invention concerne des agents antimalariaux comportant un nouveau pharmacophore de formule (I). Ces composés polycycliques sont susceptibles d''inhiber les souches sensibles à la chloroquine et résistantes à la chloroquine de Plasmodium falciparum (Pf). En outre, la synthèse de ces composés est peu onéreuse et implique peu d''étapes à partir des produits commerciaux.