927690-16-2Relevant articles and documents
Design and synthesis of potent antimalarial agents based on clotrimazole scaffold: Exploring an innovative pharmacophore
Gemma, Sandra,Campiani, Giuseppe,Butini, Stefania,Kukreja, Gagan,Joshi, Bhupendra P.,Persico, Marco,Catalanotti, Bruno,Novellino, Ettore,Fattorusso, Ernesto,Nacci, Vito,Savini, Luisa,Taramelli, Donatella,Basilico, Nicoletta,Morace, Giulia,Yardley, Vanessa,Fattorusso, Caterina
, p. 595 - 598 (2007/10/03)
Identification of new molecular scaffolds structurally unrelated to known antimalarials may represent a valid strategy to overcome resistance of P. falciparum (Pf) to currently available drugs. We describe herein the investigation of a new polycyclic phar