Country:China (Mainland)
Year Established: 2009Business type: Other
Integral:
1. Introduction of Azilsartan
Azilsartan, with the codename TAK-536, is one medicine which is applied to treat hypertension that was developed by Takeda. With the CAS registry number of 147403-03-0 and Trade names like Edarbi, Azilsartan has its Formula of C30H24N4O8 and Mol. mass of 568.53 g/mol. Besides, its IUPAC name is 2-ethoxy-3-[[4-[2-(5-oxo-2H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid.
2. Physical information of Azilsartan
Physical properties of Azilsartan are as below: (1)ACD/LogP: 5.728; (2)# of Rule of 5 Violations: 3; (3)ACD/LogD (pH 5.5): 5.37; (4)ACD/LogD (pH 7.4): 5.72; (5)ACD/BCF (pH 5.5): 5877.79; (6)ACD/BCF (pH 7.4): 13071.23; (7)ACD/KOC (pH 5.5): 13773.59; (8)ACD/KOC (pH 7.4): 30630.16; (9)#H bond acceptors: 12; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 10; (12)Polar Surface Area: 139.57; (13)Index of Refraction: 1.68; (14)Molar Refractivity: 147.765 cm3; (15)Molar Volume: 390.987 cm3; (16)Polarizability: 58.579×10-24 cm3; (17)Surface Tension: 57.1689987182617 dyne/cm; (18)Density: 1.454 g/cm3; (19)Flash Point: 406.155 °C; (20)Enthalpy of Vaporization: 109.033 kJ/mol; (21)Boiling Point: 747.965 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25°C.
3. Supply of Azilsartan
For being one angiotensin type 1 receptor blocker; receptor blocker, Azilsartan belongs to the product categories of Aromatics; Heterocycles; Intermediates & Fine Chemicals; Pharmaceuticals; Intermediates. There are many leading suppliers in China, such as Hangzhou Holypharm biotech Co.,Ltd., which is a professional supplier of active pharmaceutical ingredients and intermediates, from which you could get detailed information of Argatroban.
Argatroban is indicated as an anticoagulant for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia and an anticoagulant in patients.
Argatroban (CAS No. 74863-84-6) is an anticoagulant that is a small molecule direct thrombin inhibitor and the argatroban dose in different diseases is not the same.
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