1. Introduction of (E)-2-methyl-2-butenoic acid
(E)-2-methyl-2-butenoic acid, with the superlist name of tiglic acid, has other names like (E)-2-Methylcrotonic Acid, (E)-2,3-Dimethylacrylic acid, etc. For being a kind of colorless flake crystaline, tiglic acid has the spicy incense, and it will volatilize with the water vapor. Besides, (E)-2-methyl-2-butenoic acid is soluble in water, ethanol and ether while slightly soluble in cold water. When you need to store it, you should keep it sealed in the cool, dry and well-ventilated place. When comes to its usage, (E)-2-methyl-2-butenoic acid could be used as one kind of emulsion breaker and its esters could be applied as spice.
The toxicity information of tiglic acid could be described through the following form:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
| rabbit | LD50 | skin | > 5gm/kg (5000mg/kg) | | Food and Chemical Toxicology. Vol. 20, Pg. 837, 1982. |
| rat | LD50 | oral | > 5gm/kg (5000mg/kg) | | Food and Chemical Toxicology. Vol. 20, Pg. 837, 1982. |
2. (E)-2-methyl-2-butenoic acid product The synthesis method of
tiglic acid product:
1. Tobacco: BU, 56; FC, 18, 40; (E)-2-methyl-2-butenoic acid could be synthesis from 2-hydroxy-2-methylbutyronitrile.
2. Other tiglic acid synthesis methods are as below: (E)-2-methyl-2-butenoic acid can be achieved by 2-ethyl-acrylic acid with the temperature of 230 °C. This reaction will need reagent water with the reaction time of 3 hours. The yield is about 62%.
Tiglic acid has many leading suppliers in China, which has been one hot chemical in the domestic market. eg. Nanjing Aily Biotechnology Co.,Ltd. This company is one leading producer of Tiglic acid which is experienced in chemical manufacturing and custom synthesis.
<span style="width: 640px; color: #000000; font-size: 12px; word-break: break-all"> </span></p>
<div><font size="3" face="Arial">We are a specialized company in chemical manufacture and custom synthesis. Our factory was established in 1997, and set up <span class="scayt-misspell" data-scaytid="5" data-scayt_word="Nanjing">Nanjing</span> <span class="scayt-misspell" data-scaytid="7" data-scayt_word="Aily">Aily</span> Biotechnology Co.,Ltd in 2008. Now we have 3 OEM factories, 2 R&D labs. <span class="scayt-misspell" data-scaytid="9" data-scayt_word="Aily">Aily</span> is striving to improve <span class="scayt-misspell" data-scaytid="13" data-scayt_word="reseach">reseach</span> and development, meet social and customers needs with a unifying strategic <span class="scayt-misspell" data-scaytid="3" data-scayt_word="idea.Pls">idea.Pls</span> find our factory details as <span class="scayt-misspell" data-scaytid="15" data-scayt_word="fallowings">fallowings</span>.</font></div>
<div align="left"><font face="Arial"><font size="3">Our factory possess an area of more than 50000 meters square, which contains the office building, production facilities, labs and R&D center. We have more than 100 staff , two-thirds of them are sophisticated technicians who have engaged into chemical synthesis for a long time, and they compose the R&D team of <span class="scayt-misspell" data-scaytid="11" data-scayt_word="Aily">Aily</span> chemicals. This is a highly proficient team of chemists, engineers and technicians. Experience of many years in special chemicals enables us to offer you a variety of complex compounds. <b>From laboratory, pilot plant to large-scale production, we are prepared to execute your highly specialized requirements, including adapting existing units, building additional processing units.</b></font></font></div>
<div align="left"><font size="3" face="Arial">We own sophisticated <span class="scayt-misspell" data-scaytid="17" data-scayt_word="infrostructure">infrostructure</span>, advanced technical know-how and precise analytic instruments, the R&D center and labs are equipped with advanced R&D as well as testing appliances such as<b> GC,<span class="scayt-misspell" data-scaytid="19" data-scayt_word="HPLC">HPLC</span> UV-Vis </b>and so forth. Hence the quality of our products is reliable.</font></div>
<div align="left"><font size="3" face="Arial">We have set up long-term and stable cooperation with some world top companies. In order to improve the quality of the currents products, develop more new products and cultivate custom manufacture, we are making the best of the talents of its own technicians, meanwhile it has built stable cooperation with a large number of universities and institutes.</font></div>
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Basic Information
- Company Name:NANJING AILY BIOTECHNOLOGY CO.,LTD
- Number of Employees:
- Contact person:chen
- Street Address:B-313,No.26,Fu Hou Gang,Gu Lou District, Nanjing 210009,China
- City:nanjing
- Province/State:jiangsu
- Country/Region:China (Mainland)
- Zip:210009
- Business type:Lab/Research institutions
- Tel:+86-25-83208295
- Fax:+86-25-83208202
- Website:
- Year Established: