cholestyramine side effects， colestiramina

NANJING AILY BIOTECHNOLOGY CO.,LTD

Country:China (Mainland)

Year Established: Business type: Lab/Research institutions

Integral:

Cholestyramine,with the synonym of colestiramina,is usually applied to treat hypercholesterolemia.All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Cholestyramine :

Gastrointestinal
Gastrointestinal side effects of cholestyramine maily include constipation (28%), heartburn (17%), belching or bloating (11%), nausea (9%).Constipation is most common and can be severe. Intestinal obstruction has been reported in pediatric patients. Elderly patients are probably at risk for this as well. In one large study, gastrointestinal side effects of cholestyramine diminished with continued therapy. If gastrointestinal side effects are significant, dosage reductions, even if temporary, may be beneficial.

Metabolic
Metabolic side effects include hyperchloremic metabolic acidosis, weight loss, and weight gain. Cholestyramine has been reported to decrease the absorption of thyroxine (T4).

The mechanism by which cholestyramine causes metabolic acidosis has not been completely resolved. However, it may involve the release of chloride ions by cholestyramine (a chloride salt form) in addition to binding of bicarbonate and carbonate ions to the resin, creating a metabolic imbalance. Patients with impaired renal function may be at increased risk due to impairment of chloride elimination.

Hepatic
Hepatic side effects of cholestyramine include rare cases of abnormal liver function tests although causality is unknown. In addition, calcification in the right upper quadrant and of the biliary tree has been reported, as has biliary colic.

Cholestyramine has many leading suppliers in China, such as NANJING AILY BIOTECHNOLOGY CO.,LTD., which is a professional supplier of active pharmaceutical ingredients and intermediates. If you want to know more about cholestyramine side effects information or other detailed information about cholestyramine, you could refer to this supplier.

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