2-Nitrophenol (CAS No. 88-75-5) msds detailed information are provided by Hangzhou Chemfar Ltd., which has more than 20 years' experience focused on providing integrated development and manufacturing service to the pharmaceutical and fine chemical industry.

1. PRODUCT AND COMPANY IDENTIFICATION

Product name: 2-Nitrophenol

2. COMPOSITION/INFORMATION ON INGREDIENTS

Formula: C6H5NO3
Molecular Weight: 139.11 g/mol

3. HAZARDS IDENTIFICATION

Emergency Overview
OSHA Hazards
Toxic by ingestion, Irritant
Target Organs
Blood, Central nervous system
HMIS Classification
Health Hazard:
Flammability:
Physical hazards:
NFPA Rating
Health Hazard:
Fire:
Reactivity Hazard:
Potential Health Effects
Inhalation: May be harmful if inhaled. Causes respiratory tract irritation.
Skin: May be harmful if absorbed through skin. Causes skin irritation.
Eyes: Causes eye irritation.
Ingestion: Toxic if swallowed.

4. FIRST AID MEASURES

General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area.
If inhaled
If breathed in, move person into fresh air. If not breathing give artificial respiration Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

5. FIRE-FIGHTING MEASURES

Flammable properties
Flash point: 102.0 °C (215.6 °F) - closed cup
Ignition temperature no data available
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special protective equipment for fire-fighters
Wear self contained breathing apparatus for fire fighting if necessary.

6. ACCIDENTAL RELEASE MEASURES

Personal precautions
Use personal protective equipment. Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation.
Environmental precautions
Do not let product enter drains. Discharge into the environment must be avoided.
Methods for cleaning up
Pick up and arrange disposal without creating dust. Keep in suitable, closed containers for disposal.

7. HANDLING AND STORAGE

Handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection.
Storage
Keep container tightly closed in a dry and well-ventilated place.
Light sensitive. Keep in a dry place. Keep in a dry place.

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Contains no substances with occupational exposure limit values.
Personal protective equipment
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a dust mask type N95 (US) or type P1
(EN 143) respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Hand protection
Handle with gloves.
Eye protection
Safety glasses
Skin and body protection
Choose body protection according to the amount and concentration of the dangerous substance at the work place.
Hygiene measures
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

9. PHYSICAL AND CHEMICAL PROPERTIES

Appearance: powder
Colour: light yellow
Safety data
pH
Melting point: 45.0 °C (113.0 °F)
Boiling point: 214.0 °C (417.2 °F)
Flash point: 102.0 °C (215.6 °F) - closed cup
Ignition temperature
Lower explosion limit
Upper explosion limit
Vapour pressure: 1.3 hPa (1.0 mmHg) at 49.3 °C (120.7 °F)

10. STABILITY AND REACTIVITY

Storage stability
Stable under recommended storage conditions.
Materials to avoid
Strong oxidizing agents, Strong bases
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides, nitrogen oxides (NOx)

11. TOXICOLOGICAL INFORMATION

Acute toxicity
LD50 Oral - rat - 334.0 mg/kg
LD50 Dermal - rabbit - > 7,940 mg/kg
Remarks: Behavioral:Food intake (animal). Behavioral:Change in motor activity (specific assay).
Irritation and corrosion
no data available
Sensitisation
no data available

Chronic exposure
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
ACGIH: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH.
NTP: No component of this product present at levels greater than or equal to 0.1% is identified as
a known or anticipated carcinogen by NTP.
OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA.

Signs and Symptoms of Exposure
Absorption into the body leads to the formation of methemoglobin which in sufficient concentration causes cyanosis.
Onset may be delayed 2 to 4 hours or longer., Depending on the intensity and duration of exposure, effects may vary from mild irritation to severe destruction of tissue., prolonged or repeated exposure can cause:, Damage to the eyes.,
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.

Potential Health Effects
Inhalation: May be harmful if inhaled. Causes respiratory tract irritation.
Skin: May be harmful if absorbed through skin. Causes skin irritation.
Eyes: Causes eye irritation.
Ingestion: Toxic if swallowed.
Blood, Central nervous system,
Additional Information
RTECS: SM2100000

12. ECOLOGICAL INFORMATION

Elimination information (persistence and degradability)
no data available
Ecotoxicity effects
Toxicity to fish
Toxicity to daphnia and other aquatic invertebrates.
NOEC - Cyprinodon variegatus (sheepshead minnow) - 24 mg/l - 96 h- Pimephales promelas (fathead minnow) - 160 mg/l - 96 h EC50 - Daphnia magna (Water flea) - 17 mg/l - 48 h
Further information on ecology
An environmental hazard cannot be excluded in the event of unprofessional handling or disposal.
Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

13. DISPOSAL CONSIDERATIONS

Product
Observe all federal, state, and local environmental regulations. Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.

14. TRANSPORT INFORMATION

DOT (US)
UN-Number: 1663 Class: 6.1
Proper shipping name: Nitrophenols
Marine pollutant: No
Poison Inhalation Hazard: No

IMDG
Packing group: III
UN-Number: 1663 Class: 6.1
Proper shipping name: NITROPHENOLS
Marine pollutant: No

IATA
UN-Number: 1663 Class: 6.1
Packing group: III
Packing group: III
EMS-No: F-A, S-A
Proper shipping name: Nitrophenols

15. REGULATORY INFORMATION

OSHA Hazards
Toxic by ingestion, Irritant
DSL Status
All components of this product are on the Canadian DSL list.
SARA 302 Components
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313 Components