argatroban; 74863-84-6; Physical properties of Argatroban; Usage of Argatroban

HANGZHOU HOLYPHARM BIOTECH CO.,LTD

Country:China (Mainland)

Year Established: 2009Business type: Other

Integral:

1. Introduction of Argatroban

Argatroban, with its CAS registry number 74863-84-6, has its IUPAC Name of (2R,4R)-1-[(2S)-5-[(diaminomethylidene)amino]-2-[(3R)-3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido]pentanoyl]-4-methylpiperidine-2-carboxylic acid. Having its Chemical Formula of C₂₃H₃₆N₆O₅S and molecular weight of 508.63, this chemical is one kind of white to off-white crystalline solid. For being one a direct, selective thrombin inhibitor, it belongs to the categories of Anticoagulants and Platelet Aggregation Inhibitors. As to its storage way, argatroban could be kept at +4°C.

2. Physical properties of Argatroban

Physical properties of Argatroban are as below: (1)ACD/LogP: 2.56; (2)# of Rule of 5 Violations: 3; (3)ACD/LogD (pH 5.5): -0.43; (4)ACD/LogD (pH 7.4): -0.45; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1.02; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 11; (10)#H bond donors: 7; (11)#Freely Rotating Bonds: 8; (12)Index of Refraction: 1.674; (13)Molar Refractivity: 129.78 cm³; (14)Molar Volume: 345.7 cm³; (15)Polarizability: 51.45×10^-24 cm³; (16)Surface Tension: 61.6 dyne/cm; (17)Enthalpy of Vaporization: 122.18 kJ/mol; (18)Vapour Pressure: 4.23E-27 mmHg at 25°C; (19)Rotatable Bond Count: 9; (20)Tautomer Count: 2; (21)Exact Mass: 508.246789; (22)MonoIsotopic Mass: 508.246789; (23)Topological Polar Surface Area: 189; (24)Heavy Atom Count: 35; (25)Complexity: 887.

3. Usage of Argatroban

When comes Argatroban usage, it is widely applied as an anticoagulant in individuals with thrombosis and heparin induced thrombocytopenia. Besides, Argatroban is also be used in patients with, or at risk for, HIT who are undergoing percutaneous coronary intervention. If you need to know more about its usage, you could refer to some specialized manufacturers, such as Hangzhou Holypharm biotech Co.,Ltd. This is a professional supplier of active pharmaceutical ingredients and intermediates, from which you could get detailed information of Argatroban.

HANGZHOU HOLYPHARM BIOTECH CO.,LTD is a professional supplier of active pharmaceutical ingredients and intermediates; agrochemicals and Veterinary products. We are specialized in contract R&D and custom manufacturing. we have rich experience on a wide range of chemical reactions and fermentation from multi gram scale to hundred tons scale according to customers' requirement. Moreover, we are quite strong on registration. Our products have been registered in India, Vietnam, Latin America, Turkey, etc. HANGZHOU HOLYPHARM BIOTECH CO.,LTD is mainly engaged in the importing and exporting of pharmaceutical raw materials and intermediates to the markets of Europe and North America, and B2B e-commerce platform is undoubtedly an important platform for foreign trade enterprises who are looking for domestic opportunities. Holypharm forges their products to the foreign buyers' accustomed searching mode, which is the most effective way to advertise. We have three departments, PHARM DEPT. ,VETERINARY DEPT., AGROCHMICAL DEPT. We gather most qualified staffs with years of practical experience and knowledge in each department . They have better ideas on quality control, registration data, excellent packaging & labeling and logistics. To provide clients with more technology support, we will present efficient regulatory documents to show professional abilities in this field. Professional services The enterprise armed with knowledge will always keep its vitality and development. The human resources department in HANGZHOU HOLYPHARM will train its staff at regular intervals, to help them have a in-depth understanding of business regulations, foreign trade processes, chemical knowledge, communication skills, and so on. After foreign buyers gives the order, the company will give the one-stop services with factory-auditing, inspection, order management, export declaration to freight logistics. In addition, HANGZHOU HOLYPHARM will provide free extra services for foreign buyers like investigation of domestic market and consulting services, which is highly appraised by customers. As a company in the field of chemical export industry for many years, HOLYPHARM is engaged in improving the professional competence of the business staff and their professional services, which is not only the best way to win customers, but also helps to dig out the potential value of the chemical industry chain which are negligent.

Basic Information

Company Name：HANGZHOU HOLYPHARM BIOTECH CO.,LTD
Number of Employees：11 - 50
Contact person：Leonard
Street Address：Room D808, Block 4 NO.176, Zixia Rd
City：Hangzhou
Province/State：Zhejiang
Country/Region：China (Mainland)
Zip：310007
Business type：Other
Tel：86 571 86853097
Fax：86 571 87357695
Website：
Year Established：2009

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