Product Name

  • Name

    (+-)-METHADONE HYDROCHLORIDE--DEA

  • EINECS 214-140-7
  • CAS No. 125-56-4
  • Density 1.009g/cm3
  • Solubility
  • Melting Point 99-100oC
  • Formula C21H28ClNO
  • Boiling Point 423.7oC at 760mmHg
  • Molecular Weight 345.90612
  • Flash Point 126.5oC
  • Transport Information
  • Appearance
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 125-56-4 ((+-)-METHADONE HYDROCHLORIDE--DEA)
  • Hazard Symbols T
  • Synonyms (+-)-METHADONE HYDROCHLORIDE--DEA;(+-)-1-diphenyl-1-(2-dimethylaminopropyl)-2-butanonehydrochloride;4-diphenyl-6-dimethylamino-3-heptanonehydrochloride(+-)-;6-(dimethylamino)-4,4-diphenyl-,hydrochloride,(+-)-3-heptanon;algidon;algolysin;amidonhydrochloride;an-148
  • PSA 20.31000
  • LogP 5.09400

(+/-)-Methadone hydrochloride Chemical Properties

Empirical Formula: C21H28ClNO
Molecular Weight: 345.9061 g/mol
EINECS: 214-140-7 
Flash Point: 126.5 °C
Enthalpy of Vaporization: 67.8 kJ/mol
Boiling Point: 423.7 °C at 760 mmHg
Vapour Pressure: 2.2E-07 mmHg at 25 °C 
Structure of (+/-)-Methadone hydrochloride (CAS NO.125-56-4):
             
Systematic Name of (+/-)-Methadone hydrochloride (CAS NO.125-56-4): 6-Dimethylamino-4,4-diphenyl-heptan-3-one hydrochloride
Product Categories of (+/-)-Methadone hydrochloride (CAS NO.125-56-4): Drug / Therapeutic Agenta;Reproductive Effect

(+/-)-Methadone hydrochloride Toxicity Data With Reference

1.    

orl-mus TDLo:10,950 mg/kg/2Y-C:NEO

     FAATDF    Fundamental and Applied Toxicology. 11 (1988),640.
2.    

orl-rat LD50:95 mg/kg

     JPETAB    Journal of Pharmacology and Experimental Therapeutics. 92 (1948),269.
3.    

ipr-rat LD50:33 mg/kg

     JPETAB    Journal of Pharmacology and Experimental Therapeutics. 98 (1950),305.
4.    

orl-mus LD50:95,400 µg/kg

     JOCEAH    Journal of Organic Chemistry. 17 (1952),321.
5.    

ipr-mus LD50:31 mg/kg

     JPETAB    Journal of Pharmacology and Experimental Therapeutics. 98 (1950),305.
6.    

scu-mus LD50:27 mg/kg

     JPETAB    Journal of Pharmacology and Experimental Therapeutics. 98 (1950),305.
7.    

ivn-mus LD50:24,240 µg/kg

     BJPCAL    British Journal of Pharmacology and Chemotherapy. 4 (1949),98.
8.    

scu-dog LDLo:50 mg/kg

     JPETAB    Journal of Pharmacology and Experimental Therapeutics. 98 (1950),305.
9.    

ivn-dog LD50:29 mg/kg

     CPBTAL    Chemical and Pharmaceutical Bulletin. 7 (1959),372.

(+/-)-Methadone hydrochloride Safety Profile

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Caution: Abuse leads to habituation or addiction. When heated to decomposition it emits toxic fumes of NOx and HCl. See also METHADONE HYDROCHLORIDE.
Hazard Codes: ToxicT
Risk Statements: 25
 R25 :Toxic if swallowed.
Safety Statements: 45 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

(+/-)-Methadone hydrochloride Specification

 (+/-)-Methadone hydrochloride ,its cas register number is 125-56-4. It also can be called 1,1-Dphenyl-1-(2-dimethylaminopropyl)-2-butanone Hydrochloride ; (±)-6-(dimethylamino)-4,4-diphenyl-3-Heptanone hydrochloride ;and (±)-Methadone Hydrochloride .

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