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( -)-alpha-Narcotine Chemical Properties

Empirical Formula of ( -)-alpha-Narcotine (CAS NO.6035-40-1): C22H23NO7
Molecular Weight: 413.4205 g/mol
Index of Refraction: 1.602
Density: 1.332 g/cm3
Flash Point: 295.7 °C
Enthalpy of Vaporization: 84.91 kJ/mol
Boiling Point: 565.3 °C at 760 mmHg
Vapour Pressure: 8.42E-13 mmHg at 25 °C 
Structure of ( -)-alpha-Narcotine (CAS NO.6035-40-1):
                    

( -)-alpha-Narcotine Toxicity Data With Reference

1.    

ipr-rat LD50:750 mg/kg

    APTOA6    Acta Pharmacologica et Toxicologica. 6 (1950),235.
2.    

orl-mus LD50:2784 mg/kg

    APFRAD    Annales Pharmaceutiques Francaises. 15 (1957),640.
3.    

scu-mus LD50:491 mg/kg

    APFRAD    Annales Pharmaceutiques Francaises. 15 (1957),640.
4.    

ivn-mus LD50:83 mg/kg

    85GDA2    CRC Handbook of Antibiotic Compounds, Volumes 1-9. 8 (1)(1982),206.
5.    

ivn-dog LDLo:73 mg/kg

    CPBTAL    Chemical and Pharmaceutical Bulletin. 7 (1959),372.

( -)-alpha-Narcotine Safety Profile

Poison by intravenous route. Moderately toxic by ingestion, intraperitoneal, and subcutaneous routes. When heated to decomposition ( -)-alpha-Narcotine (CAS NO.6035-40-1) emits toxic fumes of NOx.

( -)-alpha-Narcotine Specification

 Noscapine ,its cas register number is 6035-40-1. It also can be called Noscapine dl-form ; and 6,7-Dimethoxy-3-(4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-2-benzofuran-1(3H)-one .

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