Product Name

  • Name

    BIOTIN-NHS

  • EINECS 609-055-0
  • CAS No. 35013-72-0
  • Article Data19
  • CAS DataBase
  • Density 1.45 g/cm3
  • Solubility DMF: ≤50 mg/mL Stable for at least one month in dry DMF
  • Melting Point 212-214 °C
  • Formula C14H19N3O5S
  • Boiling Point
  • Molecular Weight 341.388
  • Flash Point
  • Transport Information
  • Appearance White Solid
  • Safety 22-24/25
  • Risk Codes
  • Molecular Structure Molecular Structure of 35013-72-0 (BIOTIN-NHS)
  • Hazard Symbols
  • Synonyms 2,5-Pyrrolidinedione,1-[[5-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl]oxy]-,[3aS-(3aa,4b,6aa)]-;2,5-Pyrrolidinedione,1-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]oxy]-(9CI);(N-Hydroxysuccinimidyl)biotin;Biotin N-hydroxysuccinimide ester;BiotinN-hydroxysuccinimidyl ester;D-Biotin N-hydroxysuccinimide ester;NSC 345668;
  • PSA 130.11000
  • LogP 0.91490

(+)-Biotin N-hydroxysuccinimide ester Chemical Properties

Molecular Formula: C14H19N3O5S
Molar mass: 341.3828 g/mol
Density: 1.45 g/cm3
Form: powder
Flash Point: 174.4 °C
Storage temp: -20°C
Appearance: White solid
Index of Refraction: 1.616
Melting point: 212-214 °C
Boiling Point: 364.7 °C at 760 mmHg
Vapour Pressure: 2.59E-06 mmHg at 25°C
Solubility: DMF: ≤50 mg/mL, stable for at least one month in dry DMF
Stable: Incompatible with strong oxidizing agents.
Structure of NHS-Biotin (35013-72-0):
                      
XLogP3-AA: -0.2
H-Bond Donor: 2
H-Bond Acceptor: 5
IUPAC Name: (2,5-dioxopyrrolidin-1-yl)
5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl)pentanoate
Canonical SMILES: C1CC(=O)N(C1=O)OC(=O)CCCCC2C3C(CS2)NC(=O)N3
InChI: InChI=1S/C14H19N3O5S/c18-10-5-6-11(19)17(10)22-12(20)4-2-1-3-9-13-8(7-23-9)15-14(21)16-13/h8-9,13H,1-7H2,(H2,15,16,21) 
InChIKey: YMXHPSHLTSZXKH-UHFFFAOYSA-N
Product categories of NHS-Biotin (35013-72-0): Biotin Derivatives

(+)-Biotin N-hydroxysuccinimide ester Safety Profile

Safety Statements:
22:  Do not breathe dust
24:  Avoid contact with skin
25:  Avoid contact with eyes

(+)-Biotin N-hydroxysuccinimide ester Specification

 NHS-Biotin (35013-72-0) is cross linking reagents which also can be called for 1-((5-(2-Oxohexahydro-1H-thieno(3,4-d)imidazol-4-yl)pentanoyl)oxy)-2,5-pyrrolidinedione ; (+)-Biotin N-hydroxysuccinimide ester ; Biotinyl N-hydroxysuccinimide Ester ; 1-((5-(2-Oxohexahydro-1H-thieno(3,4-d)imidazol-4-yl)pentanoyl)oxy)-2,5-pyrrolidinedione .It can be used amino reactive biotin reagent for preparing biotinylated surfaces or polypeptides.

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