Product Name

  • Name

    (R)-(+)-THALIDOMIDE

  • EINECS
  • CAS No. 2614-06-4
  • Article Data1
  • CAS DataBase
  • Density 1.503g/cm3
  • Solubility
  • Melting Point 269-271°C
  • Formula C13H10 N2 O4
  • Boiling Point 509.7°C at 760 mmHg
  • Molecular Weight 258.233
  • Flash Point 262.1°C
  • Transport Information
  • Appearance
  • Safety Poison by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. See also THALIDOMIDE.
  • Risk Codes 61-22
  • Molecular Structure Molecular Structure of 2614-06-4 ((R)-(+)-THALIDOMIDE)
  • Hazard Symbols
  • Synonyms 1H-Isoindole-1,3(2H)-dione,2-(2,6-dioxo-3-piperidinyl)-, (R)-; Phthalimide, N-(2,6-dioxo-3-piperidyl)-,D-(+)- (8CI); (+)-(R)-Thalidomide; (+)-Thalidomide; (R)-(+)-Thalidomide;(R)-Thalidomide; NSC 91729; R-(D)-Thalidomide
  • PSA 83.55000
  • LogP 0.35450

(+)-Thalidomide Chemical Properties

Molecular Structure of (+)-Thalidomide (CAS NO. 2614-06-4):

IUPAC Name: 2-(2,6-Dioxopiperidin-3-yl)isoindole-1,3-dione 
Molecular Formula: C13H10N2O4
Molecular Weight: 258.229500 g/mol
XLogP3: 0.3
H-Bond Donor: 1
H-Bond Acceptor: 4
Canonical SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=CC=CC=C3C2=O
InChI: InChI=1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)
InChIKey: UEJJHQNACJXSKW-UHFFFAOYSA-N
Index of Refraction: 1.646
Molar Refractivity: 62.35 cm3
Molar Volume: 171.7 cm3
Surface Tension: 69.9 dyne/cm
Density: 1.503 g/cm3
Flash Point: 262.1 °C
Enthalpy of Vaporization: 78.04 kJ/mol
Boiling Point: 509.7 °C at 760 mmHg
Vapour Pressure: 1.65E-10 mmHg at 25 °C
Melting Point: 269-271°C
Appearance: white solid

(+)-Thalidomide Toxicity Data With Reference

1.    

orl-mus LD50:400 mg/kg

    NATUAS    Nature. 215 (1967),296.

(+)-Thalidomide Safety Profile

Safety Information of (+)-Thalidomide (CAS NO. 2614-06-4):
Hazard Codes: T Toxic
Risk Statements: 61-22
R61:May cause harm to the unborn child
R22:Harmful if swallowed
Safety Statements: 53-36/37/39-45
S53:Avoid exposure - obtain special instructions before use
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany: 3
RTECS: TI4925000
Poison by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. See also THALIDOMIDE.

(+)-Thalidomide Specification

  (+)-Thalidomide with cas registry number of 2614-06-4 is also known as 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-, (R)- ; D-Thalidomide ; NSC 91729 ; Phthalimide, N-(2,6-dioxo-3-piperidyl)-, (+)- ; R-(+)-Thalidomide ; d-Thalidomide ; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-, (R)- (9CI) ; Phthalimide, N-(2,6-dioxo-3-piperidyl)-, D-(+)- . It is optically active isomer of Thalidomide , which inhibits FGF-induced angiogenesis and replication of human immunodeficiency virus type 1.

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View