(1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine supplier

Name
(1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine
EINECS -0
CAS No. 29841-69-8
Article Data64
CAS DataBase
Density 1.106 g/cm³
Solubility Insoluble in water.
Melting Point 83-85 °C(lit.)
Formula C₁₄H₁₆N₂
Boiling Point 353.9 °C at 760 mmHg
Molecular Weight 212.294
Flash Point 199.9 °C
Transport Information
Appearance white to light yellow crystal powder
Safety 26-36/37/39-45
Risk Codes 34
Molecular Structure
Hazard Symbols Xi, C
Synonyms (1S,2S)-(-)-1,2-diphenylethylenediamine;[(1S,2S)-2-azaniumyl-1,2-diphenyl-ethyl]azanium;(1S,2S)-(-)-1,2-Diphenyl-1,2-ethane diamine;(1S,2S)-1,2-diphenylethylenediamide;(1S,2S)-(-)-1,2-Diphenylenediamine;(1S, 2S)-1,2-Diphenylethylenediamine;(1S,2S)-1,2-Diphenyl-1,2-ethanediamine;(1S,2S)-1,2-diphenylethane-1,2-diamine;(S,S)-diphenylethylenediamine;(1S,2S)-(-)-1,2- Diphenylethylenediamine;
PSA 52.04000
LogP 3.78700

Synthetic route

: 951-87-1, 5700-60-7, 16635-95-3, 29841-69-8, 35132-20-8, 107133-00-6
rac-1,2-diphenylethylene-1,2-diamine

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
Stage #1: rac-1,2-diphenylethylene-1,2-diamine With di-μ-Cl-bis{(SCRN)2-[1(N-i-PrNH)Et]Ph-C,N}diPd(II) In methanol for 1h; Substitution; Stage #2: With hydrogenchloride In dichloromethane for 0.0833333h; Decomposition;	85%
	60%
With L-(+)-tartaric acid Inert atmosphere;	38%

: 16118-22-2
benzylidenamine

A: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

B: 35132-20-8
(R,R)-1,2-diphenylethylenediamine

Conditions

Conditions	Yield
Stage #1: benzylidenamine With (5R,5'R)-4,4,4',4'-tetrakis(2,5-dimethylphenyl)-5,5'-diphenyl-2,2'-bi(1,3,2-dioxaborolane) In tetrahydrofuran; methanol at 20 - 30℃; Schlenk technique; Inert atmosphere; Sealed tube; Stage #2: With hydrogenchloride In methanol; water pH=Ca. 3; Catalytic behavior; Reagent/catalyst; Solvent;	A n/a B 80%
Stage #1: benzylidenamine With (5R,5'R)-5,5'-diphenyl-4,4,4',4'-tetra-o-tolyl-2,2'-bi(1,3,2-dioxaborolane) In tetrahydrofuran; methanol at 20℃; for 24h; Stage #2: With hydrogenchloride In methanol Reagent/catalyst; enantioselective reaction;	A n/a B n/a

: C4H6O6*(x)C14H16N2

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
With sodium hydroxide In dichloromethane; water at 0 - 5℃;	66%

: 137359-92-3, 137767-94-3
1,2-Diphenyl-N,N'-bis-[1,7,7-trimethyl-bicyclo[2.2.1]hept-(2E)-ylidene]-ethane-1,2-diamine

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
With hydroxylamine acetate In ethanol for 24h; Heating;	50%

: (+)-(1S,2S)-N-acetyl-N'-benzoyl-1,2-diamino-1,2-diphenylethane

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
With hydrogen bromide; acetic acid	49%

: 911306-54-2
(+)-(1S,2S)-N-[(R)-α-acetoxyphenylacetyl]-N'-benzoyl-1,2-diamino-1,2-diphenylethane

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
With hydrogen bromide In acetic acid for 26h; Heating;	34%

: 132486-62-5
(+)-(1S,2S)-1,2-diphenylethane-1,2-diazide

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In ethyl acetate under 38000 Torr; Yield given;
With lithium aluminium tetrahydride In diethyl ether

: threo-1,2-diphenyl-1,2-ethanediamin

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: (S,S)-(-)-1,2-diphenylethane-1,2-diamine D-mandelate

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 23873-81-6
benzildioxime

A: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

B: 951-87-1, 5700-60-7, 16635-95-3, 29841-69-8, 35132-20-8, 107133-00-6
meso-1,2-diphenyl-1,2-diaminoethane

C: 35132-20-8
(R,R)-1,2-diphenylethylenediamine

Conditions

Conditions	Yield
With sodium In ethanol for 0.166667h; Heating; Yield given. Yields of byproduct given;

...Expand

: 5700-60-7
1,2-Diphenylethylenediamine

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
via co-crystalization with N*-chiral dimeric ortho-palladated matrix SCRN-L>PdCl>2 L=2-<1-(N-isopropylamino)ethyl>phenyl-CN;

ditartrate of inactive α.α'-diphenyl-ethylenediamine: ditartrate of inactive α.α'-diphenyl-ethylenediamine

A: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 951-87-1, 5700-60-7, 16635-95-3, 29841-69-8, 35132-20-8, 107133-00-6
1,2-diphenylethane-1,2-diamine

Conditions

Conditions	Yield
With water Durch fraktionierte Krystallisation;

: 133815-20-0
(-)-(4S,5S)-4,5-dihydro-2,4,5-triphenyl-1H-imidazole

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: NaOAc 1.2: 95 percent / HCl / H2O 2.1: 49 percent / HBr; AcOH View Scheme

: 33722-46-2
isoamarine

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: NaOAc 1.2: 95 percent / HCl / H2O 2.1: 49 percent / HBr; AcOH View Scheme
Multi-step reaction with 3 steps 1: 68 percent / dicyclohexylcarbodiimide / CH2Cl2 / -20 - 20 °C 2: 92 percent / HCl / H2O; tetrahydrofuran / 2 h / Heating 3: 34 percent / aq. HBr / acetic acid / 26 h / Heating View Scheme
Multi-step reaction with 2 steps 1: 1) Ac2O, 2) dil. HCl, 3) aq. HBr / 3) AcOH, reflux 2: 60 percent View Scheme

: 911306-52-0
(-)-(4S,5S)-1-[(R)-α-acetoxyphenylacetyl]-4,5-dihydro-2,4,5-triphenyl-1H-imidazole

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 92 percent / HCl / H2O; tetrahydrofuran / 2 h / Heating 2: 34 percent / aq. HBr / acetic acid / 26 h / Heating View Scheme

: (-)-(4RS,5RS)-1-[(R)-α-acetoxyphenylacetyl]-4,5-dihydro-2,4,5-triphenyl-1H-imidazole

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: HCl / H2O; tetrahydrofuran / 2 h / Heating 2: 34 percent / aq. HBr / acetic acid / 26 h / Heating View Scheme

: 573-33-1, 973-15-9, 24427-33-6, 33722-46-2, 37134-88-6, 133815-20-0
DL-(4R,5S)-2,4,5-triphenyl-4,5-dihydro-1H-imidazole

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 70 percent / aq. NaOH / bis-(2-hydroxy-ethyl) ether / 0.75 h / 155 °C 2: 68 percent / dicyclohexylcarbodiimide / CH2Cl2 / -20 - 20 °C 3: 92 percent / HCl / H2O; tetrahydrofuran / 2 h / Heating 4: 34 percent / aq. HBr / acetic acid / 26 h / Heating View Scheme
Multi-step reaction with 3 steps 1: 87 percent / aq. NaOH / bis-(2-hydroxy-ethyl) ether / 155 °C 2: 1) Ac2O, 2) dil. HCl, 3) aq. HBr / 3) AcOH, reflux 3: 60 percent View Scheme

: 183184-04-5
(R,R)-(+)-4,5-diphenyl-1,3,2-dioxathiolan-2-one

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 81 percent / LiN3 / dimethylformamide / 120 °C 2: pyridine 3: LiN3 / dimethylformamide / 120 °C 4: H2 / 10percent Pd/C / ethyl acetate / 38000 Torr View Scheme

: 52340-78-0
(R,R)-hydroxybenzoin

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1: 100 percent / SOCl2 / CCl4 / Heating 2: 81 percent / LiN3 / dimethylformamide / 120 °C 3: pyridine 4: LiN3 / dimethylformamide / 120 °C 5: H2 / 10percent Pd/C / ethyl acetate / 38000 Torr View Scheme
Multi-step reaction with 3 steps 1: pyridine 2: NaN3 / dimethylformamide 3: LiAlH4 / diethyl ether View Scheme

: 133522-22-2
(1R,2S)-2-azido-1,2-diphenylethan-1-ol

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: pyridine 2: LiN3 / dimethylformamide / 120 °C 3: H2 / 10percent Pd/C / ethyl acetate / 38000 Torr View Scheme

: Methanesulfonic acid (1R,2S)-2-azido-1,2-diphenyl-ethyl ester

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: LiN3 / dimethylformamide / 120 °C 2: H2 / 10percent Pd/C / ethyl acetate / 38000 Torr View Scheme

: 132486-61-4
(-)-(1R,2R)-1,2-diphenyl-1,2-ditosyloxyethane

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: NaN3 / dimethylformamide 2: LiAlH4 / diethyl ether View Scheme

: 103-30-0
(E)-1,2-diphenyl-ethene

sodium powder: sodium powder

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: (i) NaN3, Fe2(SO4)3, (ii) H2O2, (iii) Sn, aq. HCl View Scheme

: C14H16N2*C33H24N2O7

A: C33H24N2O7

B: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
In ethanol; water Equilibrium constant; enantioselective reaction;

: 1236286-39-7
C14H16N2*C47H38O4

A: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

B: 137365-09-4
[(4R,5R)-2,2-dimethyl-1,3-dioxolan-4,5-diyl]bis(dinaphthalen-2-ylmethanol)

Conditions

Conditions	Yield
In chloroform-d1 Equilibrium constant;

: 5700-60-7
1,2-Diphenylethylenediamine

A: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

B: 35132-20-8
(R,R)-1,2-diphenylethylenediamine

Conditions

Conditions	Yield
With chiral stationary phase including isopropyl-functionalized CF6 In methanol; acetic acid; triethylamine; acetonitrile at 0℃; Purification / work up;

: 1414364-68-3
N-benzoyl-N'-benzylidene-meso-1,2-diphenyl-ethylendiamine

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
With sulfuric acid for 1h; Reflux;

: 4,5-diphenyl-4,5-dihydro-1H-imidazole

A: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

B: 35132-20-8
(R,R)-1,2-diphenylethylenediamine

Conditions

Conditions	Yield
With barium(II) hydroxide In water at 80℃; for 23h; Overall yield = 93 %; enantioselective reaction;	A n/a B n/a

: 5396-98-5
2,2-ppirocyclohexane-4,5-diphenyl-2H-imidazole

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: ammonia; lithium / tetrahydrofuran; ethanol / -78 - -65 °C / Inert atmosphere 1.2: -65 °C / Inert atmosphere 1.3: 0 °C / Inert atmosphere 2.1: ethanol / 20 - 70 °C 3.1: sodium hydroxide / water; dichloromethane / 0 - 5 °C View Scheme

: 1121-60-4
pyridine-2-carbaldehyde

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: (1S,2S)-N,N'-bis(2-pyridylmetheno)-1,2-diphenylethylenediimine

Conditions

Conditions	Yield
In benzene for 2h; Heating;	100%
In methanol	22%

: 50-00-0
formaldehyd

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: (4S,5S)-1,3-Dimethyl-4,5-diphenyl-imidazolidine

Conditions

Conditions	Yield
With formic acid Heating;	100%

: 824-72-6
P,P-dichlorophenylphosphine oxide

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: (S3,S4)-1-phenyl-(3,4-diphenyl)diazaphospholidine 1-oxide

Conditions

Conditions	Yield
With triethylamine In dichloromethane	100%

: 75-15-0
carbon disulfide

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 246868-60-0
(4S,5S)-4,5-diphenylimidazolidine-2-thione

Conditions

Conditions	Yield
In ethanol at 95℃; for 4h; Inert atmosphere;	100%
In ethanol at 95℃;

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 24395-14-0, 149769-84-6, 151003-26-8, 62596-62-7
(R)-2-phenyl-N-tosylaziridine

: 1244040-50-3
4-methyl-N-[(1R)-2-{[(1S,2S)-2-{[(2R)-2-(4-methylbenzenesulfonamido)-2-phenylethyl]amino}-1,2-diphenylethy]amino}-1-phenylethyl]benzene-1-sulfonamido

Conditions

Conditions	Yield
In acetonitrile Reflux;	100%
In acetonitrile for 72h; Inert atmosphere; Reflux;	74%
In acetonitrile for 72h; Reflux;	74%

: RuBr2[(S,S)-xylskewphos]

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: C51H62Br2N2P2Ru

: C51H62Br2N2P2Ru

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 25℃; for 17h; Inert atmosphere; Schlenk technique;	A 100% B n/a

...Expand

: 578-57-4
2-bromoanisole

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: (1R,2R)-N1,N2-bis(2-methoxyphenyl)-1,2-diphenylethane-1,2-diamine

Conditions

Conditions	Yield
Stage #1: (S,S)-1,2-diphenyl-1,2-diaminoethane With tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate In toluene at 20℃; for 1.5h; Inert atmosphere; Schlenk technique; Glovebox; Stage #2: 2-bromoanisole In toluene at 120℃; for 9h; Inert atmosphere; Schlenk technique; Glovebox;	100%

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 1,1′-((1R,2R)-1,2-diphenylethane-1,2-diyl)bis(3-(5-(tert-butyl)-3-formyl-2-hydroxybenzyl)-1H-imidazol-3-ium)dichloride

: (1R,2R)-(-)-N,N′-bis(3-tert-butyl-5-diyl-1-ylmethyl-salicyliden)-[(1R,2R)-1,2-di(1H-imidazol-3-ium)-1,2-diphenylethane]-1,2-diphenylethan-diamin-dichloride

Conditions

Conditions	Yield
In ethanol at 20℃; for 20h; Inert atmosphere; Molecular sieve;	100%

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: (Ra)-1,1′-(6,6′-dimethyl-[1,1′-biphenyl]-2,2′-diyl)bis(3-(5-(tert-butyl)-3-formyl-2-hydroxybenzyl)-1H-imidazol-3-ium)dichloride

: (1R,2R)-(-)-N,N′-bis(3-tert-butyl-5-diyl-1-ylmethyl-salicyliden)-[(Ra)-1,1′-(6,6′-dimethyl-[1,1′-biphenyl]-2,2′-diyl)bis(1H-imidazol-3-ium)]-1,2-diphenylethan-diamin-dichloride

Conditions

Conditions	Yield
In ethanol at 20℃; for 20h; Inert atmosphere; Molecular sieve;	100%

: 10334-26-6
(R)-camphorquinone

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 287379-86-6
(1R,4S,5S)-4,5-diphenyl-1,11,11-trimethyl-3,6-diazatricyclo[6.2.1.02,7]undeca-2,6-diene

Conditions

Conditions	Yield
In benzene Condensation; Heating;	99%

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 298-12-4
Glyoxilic acid

: (4S,5S)-4,5-diphenylimidazolidine-2-carboxylic acid

Conditions

Conditions	Yield
In dichloromethane for 16h;	99%
In dichloromethane for 16h;	99%

: RuCl2{2,2'-bis(diphenylphosphinyl)benzophenone}(DMF)n

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: RuCl2{2,2'-bis(diphenylphosphinyl)benzophenone}{(S,S)-diphenylethylenediamine}

Conditions

Conditions	Yield
In dichloromethane for 0.5h;	99%

: RuCl2{2-diphenylphosphinobenzhydrol}(DMF)n

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: RuCl2{2-diphenylphosphinobenzhydrol}{(S,S)-diphenylethylenediamine}

Conditions

Conditions	Yield
In dichloromethane for 0.5h;	99%

: RuCl2{bis(2-diphenylphosphinophenyl)ether}(DMF)n

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: RuCl2{bis(2-diphenylphosphinophenyl)ether}{(S,S)-diphenylethylenediamine}

Conditions

Conditions	Yield
In dichloromethane for 0.5h;	99%

: [Rh{2,2'-bis(diphenylphosphinyl)benzophenone}(cod)(SbF6)]

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: RhCl2{2,2'-bis(diphenylphosphinyl)benzophenone}{(S,S)-diphenylethylenediamine}(SbF6)

Conditions

Conditions	Yield
With hydrogen In dichloromethane for 1h;	99%

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 23095-31-0
3,4-dimethoxybenzene-1-sulfonyl chloride

: 953805-42-0
(S,S)-N-(2-amino-1,2-diphenyl-ethyl)-3,4-dimethoxy-benzenesulfonamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃;	99%

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 541-41-3
chloroformic acid ethyl ester

: 234753-20-9
diethyl ((1S,2S)-1,2-diphenylethane-1,2-diyl)dicarbamate

Conditions

Conditions	Yield
With potassium carbonate In tetrahydrofuran; water at 0 - 20℃; for 4h;	98%
In ethanol Ambient temperature;
With pyridine In benzene for 2h;

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 40138-16-7
2-formylbenzene boronic acid

: 18531-94-7
(R)-1,1'-Bi-2-naphthol

: (4S,5S)-2-(2-((Ra)-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaborepin-4-yl)phenyl)-4,5-diphenylimidazolidine

Conditions

Conditions	Yield
In chloroform at 20℃; for 1h;	98%

...Expand

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 29180-98-1
2-bromo-4-methyl-1,1'-biphenyl

: 1192944-48-1
C27H26N2

Conditions

Conditions	Yield
With palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate In toluene at 110℃; for 48h; Buchwald-Hartwig Coupling; Schlenk technique; Inert atmosphere;	98%
With palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate In toluene at 100℃; for 10h; Inert atmosphere;	86.3%

: 41077-10-5, 35886-08-9, 1266828-65-2
di-μ-chlorobis[1-[2-(di-tert-butulphosphino)phenyl]ethyl-C1,P]dipalladium(II)

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: (R,SS)/(S,SS)-[1-[2-(di-tert-butulphosphino)phenyl]ethyl-C1,P](1,2-diphenylethane-1,2-diamine-N,N)palladium(II) chloride

Conditions

Conditions	Yield
In methanol (Ar, Schlenk) a suspn. of dimer and diamine in anhyd. CH3OH was stirred for 1 h at room temp.; filtered, evapd. to dryness;	98%

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 2208-07-3
ethyl acetimidate hydrochloride

: 109830-48-0, 133815-21-1
(4S,5S)-2-methyl-4,5-diphenyl-4,5-dihydro-1H-imidazole

Conditions

Conditions	Yield
In ethanol at 0 - 20℃; for 12h; Inert atmosphere;	98%

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 298-12-4
Glyoxilic acid

: (4R,5R)-4,5-diphenyl-4,5-dihydro-1H-imidazole

Conditions

Conditions	Yield
With N-Bromosuccinimide In methanol at 20℃; for 1h; Inert atmosphere;	98%
Stage #1: (S,S)-1,2-diphenyl-1,2-diaminoethane; Glyoxilic acid In methanol Stage #2: With N-Bromosuccinimide	98%
With N-Bromosuccinimide

: 700-16-3
Pentafluoropyridine

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: (S,S)-N,N’-bis(2,3,5,6-tetrafluoropyridin-4-yl)-1,2-diphenylethane-1,2-diamine

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran for 24h; Inert atmosphere; Reflux; regioselective reaction;	98%

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: Ru(OAc)2(CO)((R)-Josiphos)

: [Ru(OAc)(CO)((S,S)-dpen)(R-Josiphos)]OAc

Conditions

Conditions	Yield
In (2)H8-toluene at 20℃; for 2h;	98%

: 358-23-6
trifluoromethylsulfonic anhydride

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 121788-77-0
(1S,2S)-1,2-diphenyl-N,N'-bis(trifluoromethanesulfonyl)ethane-1,2-diamine

Conditions

Conditions	Yield
With triethylamine In dichloromethane	97%
With dmap; triethylamine In dichloromethane at -78 - 20℃;	69%
With dmap; triethylamine In dichloromethane at -78 - 20℃; for 0.5h; Inert atmosphere;	57%

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 103-71-9
phenyl isocyanate

: (+)-(1S,2S)-N,N'-dimethyl-1,2-diphenylethylenyl-diphenyl-diurea

Conditions

Conditions	Yield
In dichloromethane Ambient temperature;	97%

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 153759-58-1
5-bromo-3-tert-butyl-2-hydroxybenzaldehyde

: (S,S)-2,2'-[(1,2-diphenyl-1,2-ethanediyl)bis(nitrilomethylidyne)]bis[4-bromo-6-(1,1-dimethylethy)phenol]

Conditions

Conditions	Yield
In ethanol for 1h; Heating;	97%

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 90-02-8
salicylaldehyde

: 41013-29-0, 41013-30-3, 51208-40-3, 58520-13-1, 61045-68-9, 61045-69-0, 132295-13-7
N,N'-Disalicyliden-meso-1,2-diphenylethylendiamin

Conditions

Conditions	Yield
With sodium sulfate In methanol for 12h; Ambient temperature;	97%

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 132939-08-3
2-Hydroxy-2'-methoxy-<1,1'-biphenyl>-3-carboxaldehyde

: C42H36N2O4

Conditions

Conditions	Yield
In ethanol at 20℃; for 24h;	97%

: 29841-69-8
(S,S)-1,2-diphenyl-1,2-diaminoethane

: 18506-04-2
5-chloro-5H-dibenzo[a,d]cycloheptene

: 858370-95-3
(S,S)-N,N'-bis(5H-dibenzo[a,d]cyclohepten-5-yl)-1,2-diphenyl-1,2-ethylenediamine

Conditions

Conditions	Yield
With triethylamine In dichloromethane for 0.166667h; Heating;	97%
Stage #1: (S,S)-1,2-diphenyl-1,2-diaminoethane; 5-chloro-5H-dibenzo[a,d]cycloheptene In dichloromethane at 20℃; for 2.16667h; Stage #2: With potassium carbonate In dichloromethane; water	97%
In dichloromethane at 20℃; for 2.16667h;	97%

(1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine Specification

The (1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine, with the CAS registry number 29841-69-8, is also known as 1,2-Ethanediamine, 1,2-diphenyl-, (1S,2S)-. It belongs to the product categories of Chiral; Chiral reagent; Chiral compounds; Amines (Chiral); Analytical Chemistry; Asymmetric Synthesis; Chiral Building Blocks; e.e. / Absolute Configuration Determination (NMR); Enantiomer Excess & Absolute Configuration Determination; Synthetic Organic Chemistry; Amines and Derivatives; Chiral chemicals; Chiral Compound. Its IUPAC name is called (1S,2S)-1,2-diphenylethane-1,2-diamine. You should store it in a tightly-sealed container(2 ºC -8 ºC) which is white to light yellow crystal powder.

Physical properties of (1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine: (1)ACD/LogP: 1.60; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 2; (4)#H bond donors: 4; (5)#Freely Rotating Bonds: 5; (6)Index of Refraction: 1.619; (7)Molar Refractivity: 67.36 cm³; (8)Molar Volume: 191.8 cm³; (9)Surface Tension: 50.5 dyne/cm; (10)Density: 1.106 g/cm³; (11)Flash Point: 199.9 °C; (12)Enthalpy of Vaporization: 59.89 kJ/mol; (13)Boiling Point: 353.9 °C at 760 mmHg; (14)Vapour Pressure: 3.48E-05 mmHg at 25°C.

Uses of (1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine: it is widely used in asymmetric synthesis and optical resolution, such as asymmetric hydroxylation of olefins, asymmetric aldol condensation, asymmetric Diels-Alder reaction, asymmetric carbonyl allylation reaction.

When you are using this chemical, please be cautious about it as the following:
This chemical may cause inflammation to the skin or other mucous membranes and may destroy living tissue on contact. Causes burns. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Whenever you will contact it, please wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell seek medical advice immediately (show the label where possible).

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C1=CC=C(C=C1)C(C(C2=CC=CC=C2)N)N
(2)Isomeric SMILES: C1=CC=C(C=C1)[C@@H]([C@H](C2=CC=CC=C2)N)N
(3)InChI: InChI=1S/C14H16N2/c15-13(11-7-3-1-4-8-11)14(16)12-9-5-2-6-10-12/h1-10,13-14H,15-16H2/t13-,14-/m0/s1
(4)InChIKey: PONXTPCRRASWKW-KBPBESRZSA-N

Product Name

(1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine

Synthetic route

(1S,2S)-(-)-1,2-Diphenyl-1,2-ethanediamine Specification

Related Products

Hot Products