(2-Trifluoromethyl-pyridin-3-yl)-methanol

The systematic name of (2-Trifluoromethyl-pyridin-3-yl)-methanol is [2-(trifluoromethyl)-3-pyridyl]methanol. With the CAS registry number 131747-57-4, it is also named as 3-Pyridinemethanol,2-(trifluoromethyl)-. The product's categories are Building Blocks; Pyridine. In addition, its molecular formula is C₇H₆F₃NO and molecular weight is 177.1238.

The other characteristics of (2-Trifluoromethyl-pyridin-3-yl)-methanol can be summarized as: (1)ACD/LogP: 0.11; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.11; (4)ACD/LogD (pH 7.4): 0.11; (5)#H bond acceptors: 2; (6)#H bond donors: 1; (7)#Freely Rotating Bonds: 2; (8)Polar Surface Area: 33.12 Å²; (9)Index of Refraction: 1.462; (10)Molar Refractivity: 35.77 cm³; (11)Molar Volume: 129.9 cm³; (12)Polarizability: 14.18×10^-24cm³; (13)Surface Tension: 33.2 dyne/cm; (14)Density: 1.362 g/cm³; (15)Flash Point: 80.1 °C; (16)Enthalpy of Vaporization: 47.05 kJ/mol; (17)Boiling Point: 208.8 °C at 760 mmHg; (18)Vapour Pressure: 0.126 mmHg at 25 °C.

Uses of (2-Trifluoromethyl-pyridin-3-yl)-methanol: it can be used to produce 2-trifluoromethyl-pyridine-3-carbaldehyde.



This reaction needs DMSO, N,N'-dicyclohexylcarbodiimide, H₃PO₄ at ambient temperature for 1.5 hours. The yield is 76 %.

People can use the following data to convert to the molecule structure.
(1)SMILES: c1cc(c(nc1)C(F)(F)F)CO
(2)InChI: InChI=1/C7H6F3NO/c8-7(9,10)6-5(4-12)2-1-3-11-6/h1-3,12H,4H2
(3)InChIKey: BQDXBKVSCIWSIJ-UHFFFAOYAT
(4)Std. InChI: InChI=1S/C7H6F3NO/c8-7(9,10)6-5(4-12)2-1-3-11-6/h1-3,12H,4H2
(5)Std. InChIKey: BQDXBKVSCIWSIJ-UHFFFAOYSA-N