• Name

  (R)-(+)-Propylene oxide

• EINECS 604-958-6
• CAS No. 15448-47-2
• Article Data80
• CAS DataBase
• Density 0.904 g/cm³
• Solubility Miscible with water and many organic solvents.
• Melting Point -111.91°C (estimate)
• Formula C₃H₆O
• Boiling Point 32.899 °C at 760 mmHg
• Molecular Weight 58.08
• Flash Point -31 °F
• Transport Information UN 1280 3/PG 1
• Appearance Colorless to light yellow liquid
• Safety 45
• Risk Codes 12-25
• Molecular Structure
• Hazard Symbols F+, T
• Synonyms d-Propylene oxide;Oxirane,methyl-, (2R)- (9CI);Oxirane, methyl-, (R)-;Propylene oxide, (R)-(+)- (8CI);(+)-(R)-Propylene oxide;(+)-Methyloxirane;(+)-Propylene oxide;(2R)-2-Methyloxirane;(2R)-Methyloxirane;(R)-(+)-1,2-Epoxypropane;(R)-(+)-Methyloxirane;(R)-(+)-Propylene oxide;(R)-1,2-Epoxypropane;(R)-2-Methyloxirane;(R)-Methyloxirane;(R)-Propenoxide;(R)-Propylene oxide;
• PSA 12.53000
• LogP 0.40510

Synthetic route

4248-19-5

tert-butyl carbamate

75-56-9, 16033-71-9

methyloxirane

A

167938-56-9

tert-butyl [(2S)-2-hydroxypropyl]carbamate

B

15448-47-2

(R)-propylene oxide

Conditions

Conditions	Yield
With air; 4-nitro-benzoic acid; (R,R)-((t-Bu)4-salen)Co(II) In various solvent(s) at 20℃; for 24h;	A 99% B n/a

...Expand

75-56-9, 16033-71-9

methyloxirane

15448-47-2

(R)-propylene oxide

Conditions

Conditions	Yield
With epoxyhydrolase ECU1040 In water at 0 - 20℃; for 24h; Temperature; Enzymatic reaction;	92.3%
With (R,R)-Jacobsen catalyst; acetic acid In water; toluene at 0 - 20℃; for 20h;	76%
With bis(triphenylphosphine)iminium acetate; C64H74Cl2Co2N4O4 In toluene at 0℃; for 1.5h; Resolution of racemate; Inert atmosphere; optical yield given as %ee;	49%

(R)-(+)-Propylene oxide Chemical Properties

(R)-(+)-Propylene oxide Uses

(R)-(+)-Propylene oxide Toxicity Data With Reference

(R)-(+)-Propylene oxide Safety Profile