Product Name

  • Name

    (R)-3-Isopropyl-2,5-piperazinedione

  • EINECS
  • CAS No. 143673-66-9
  • Article Data8
  • CAS DataBase
  • Density 1.087 g/cm3
  • Solubility 23 g/L (22 °C) in water
  • Melting Point 258-262 °C(lit.)
  • Formula C7H12N2O2
  • Boiling Point 445.7 °C at 760 mmHg
  • Molecular Weight 156.18
  • Flash Point 216.6 °C
  • Transport Information
  • Appearance white to light yellow crystal powder
  • Safety 22-24/25-36/37/39-26
  • Risk Codes 36/37/38-20/21/22
  • Molecular Structure Molecular Structure of 143673-66-9 ((R)-3-Isopropyl-2,5-piperazinedione)
  • Hazard Symbols HarmfulXn
  • Synonyms 2,5-Piperazinedione,3-(1-methylethyl)-, (R)-;(R)-(-)-3-Isopropyl-2,5-piperazinedione;(R)-3-Isopropylpiperazine-2,5-dione;
  • PSA 58.20000
  • LogP -0.08540

(R)-3-Isopropyl-2,5-piperazinedione Chemical Properties

IUPAC Name: (3R)-3-Propan-2-ylpiperazine-2,5-dione
Synonyms of (R)-3-Isopropyl-2,5-piperazinedione (CAS NO.143673-66-9): (R)-3-Isopropyl-piperazine-2,5-dione ; 2,5-Piperazinedione,3-(1-methylethyl)-,(3R)-(9CI) ; (R)-3-Isopropyl-2 5-piperazinedione 98% ; (R)-3-Isopropyl-2,5-piperazinedione,98%
CAS NO: 143673-66-9
Molecular Formula: C7H12N2O2
Molecular Weight: 156.18
Molecular Structure:
H bond acceptors: 4
H bond donors: 2
Freely Rotating Bonds: 1
Index of Refraction: 1.459
Molar Refractivity: 39.26 cm3
Molar Volume: 143.6 cm3
Surface Tension: 32.7 dyne/cm
Density: 1.087 g/cm3
Flash Point: 216.6 °C
Enthalpy of Vaporization: 70.37 kJ/mol
Boiling Point: 445.7 °C at 760 mmHg
Vapour Pressure: 3.87E-08 mmHg at 25°C
Melting Point: 258-262 °C(lit.)
Appearance: white to light yellow crystal powder
Alpha -31.5 º (c=1, water)
Water Solubility : 23 g/L (22 ºC)
Product Categories: ISOPROPYL;pharmacetical;Chiral Building Blocks;Heterocyclic Building Blocks;Piperazines

(R)-3-Isopropyl-2,5-piperazinedione Safety Profile

Hazard Codes: HarmfulXn
Risk Statements: 36/37/38-20/21/22
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed. 
R36/37/38: (R)-3-Isopropyl-2,5-piperazinedione (CAS NO.143673-66-9) is irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-36/37/39-26
S22: Do not breathe dust. 
S24/25: Avoid contact with skin and eyes. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany: 3
F: 3-10

(R)-3-Isopropyl-2,5-piperazinedione Specification

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Dangerous fire hazard in the form of dust when exposed to heat or flame.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. 
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Use only in a chemical fume hood.
Storage: Store (R)-3-Isopropyl-2,5-piperazinedione (CAS NO.143673-66-9) in a cool, dry place. Store in a tightly closed container.

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