-
Name
Glibornuride
- EINECS
- CAS No. 26944-48-9
- Density 1.3g/cm3
- Solubility
- Melting Point 192-195° (ethanol-water); also reported as 195-198°
- Formula C18H26 N2 O4 S
- Boiling Point °Cat760mmHg
- Molecular Weight 366.481
- Flash Point °C
- Transport Information
- Appearance
- Safety Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of SOx and NOx.
- Risk Codes
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Molecular Structure
- Hazard Symbols
- Synonyms Benzenesulfonamide,N-[[(3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-yl)amino]carbonyl]-4-methyl-,[1S-(endo,endo)]-; Urea, 1-(2-hydroxy-3-bornyl)-3-(p-tolylsulfonyl)-,(1R,2R,3S,4S)- (8CI); Glibornuride; Gluboride; Glutril; Ro 6-4563; Ro 6-4563/8;endo, endo-1-[(1R)-(2-Hydroxy-3-bornyl)]-3-(p-tolylsulfonyl)urea;endo,endo-1-(2-Hydroxy-3-bornyl)-3-(p-tolylsulfonyl)urea
- PSA 107.37000
- LogP 3.84460
1-(6-Hydroxy-1,7,7-trimethyl-5-bicyclo[2.2.1]heptanyl)-3-(4-methylphenyl)sulfonylurea Chemical Properties
IUPAC Name: 1-(6-Hydroxy-1,7,7-trimethyl-5-bicyclo[2.2.1]heptanyl)-3-(4-methylphenyl)sulfonylurea
CAS: 26944-48-9
The Molecular formula of 1-(6-Hydroxy-1,7,7-trimethyl-5-bicyclo[2.2.1]heptanyl)-3-(4-methylphenyl)sulfonylurea (CAS NO.26944-48-9): C18H26N2O4S
The Molecular Weight of 1-(6-Hydroxy-1,7,7-trimethyl-5-bicyclo[2.2.1]heptanyl)-3-(4-methylphenyl)sulfonylurea (CAS NO.26944-48-9): 366.47504
The Molecular Structure of f 1-(6-Hydroxy-1,7,7-trimethyl-5-bicyclo[2.2.1]heptanyl)-3-(4-methylphenyl)sulfonylurea (CAS NO.26944-48-9):
Density: 1.3 g/cm3
Index of Refraction: 1.6
Molar Refractivity: 95.94 cm3
Molar Volume: 280.2 cm3
Polarizability: 38.03×10-24cm3
Surface Tension: 56.5 dyne/cm
Water Solubility: 17.15(mg/L) at 25°C
1-(6-Hydroxy-1,7,7-trimethyl-5-bicyclo[2.2.1]heptanyl)-3-(4-methylphenyl)sulfonylurea Toxicity Data With Reference
| 1. | orl-rat LD50:18 g/kg | KSRNAM Kiso to Rinsho. Clinical Report. 6 (1972),1925. | ||
| 2. | ipr-rat LD50:1360 mg/kg | KSRNAM Kiso to Rinsho. Clinical Report. 6 (1972),1925. | ||
| 3. | scu-rat LD50:10,800 mg/kg | KSRNAM Kiso to Rinsho. Clinical Report. 6 (1972),1925. | ||
| 4. | ipr-mus LD50:1530 mg/kg | KSRNAM Kiso to Rinsho. Clinical Report. 6 (1972),1925. | ||
| 5. | scu-mus LD50:20 g/kg | KSRNAM Kiso to Rinsho. Clinical Report. 6 (1972),1925. |
1-(6-Hydroxy-1,7,7-trimethyl-5-bicyclo[2.2.1]heptanyl)-3-(4-methylphenyl)sulfonylurea Safety Profile
Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of SOx and NOx.
1-(6-Hydroxy-1,7,7-trimethyl-5-bicyclo[2.2.1]heptanyl)-3-(4-methylphenyl)sulfonylurea Specification
1-(6-Hydroxy-1,7,7-trimethyl-5-bicyclo[2.2.1]heptanyl)-3-(4-methylphenyl)sulfonylurea with CAS number of 26944-48-9 is also known as Glibornuride ; 1-[p-Tolylsulfonyl]-3-[2-endo-hydroxy-3-endo-D-bornyl] urea ; Glitrim ; N-[[[(1S,2S,3R,4R)-2-Hydroxyborn-3-yl]amino]carbonyl]-4-methylbenzenesulfonamide ; Ro-6-4563 . It can be used as Hypoglycemic.
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