-
Name
PROGUANIL HYDROCHLORIDE
- EINECS
- CAS No. 637-32-1
- Density
- Solubility
- Melting Point 249-2510C
- Formula C11H16 Cl N5 . Cl H
- Boiling Point 402.7oC at 760 mmHg
- Molecular Weight 290.195
- Flash Point 197.4oC
- Transport Information
- Appearance
- Safety Poison by ingestion and intravenous routes. Experimental reproductive effects. An antimalarial drug. When heated to decomposition it emits very toxic fumes of Cl− and NOx.
- Risk Codes 25
-
Molecular Structure
- Hazard Symbols T
- Synonyms Biguanide,1-(p-chlorophenyl)-5-isopropyl-, monohydrochloride (8CI); Imidodicarbonimidicdiamide, N-(4-chlorophenyl)-N'-(1-methylethyl)-, monohydrochloride (9CI);1-(p-Chlorophenyl)-5-isopropylbiguanide hydrochloride; 3359 RP; Chloroguanidehydrochloride; Chloroquanil; Diguanyl; Drinupal; Drinupal hydrochloride; Guanatol;Guanatol hydrochloride; M 4888; Paludrine; Paludrine hydrochloride; Palusil;Palusil hydrochloride; Proguanil hydrochloride; RP 3359; SN 12,837; SN 12837;Tirian; Tirian hydrochloride
- PSA 83.79000
- LogP 4.06530
1-(p-CHLOROPHENYL)-5-ISOPROPYLBI GUANIDE HYDROCHLORIDE Chemical Properties
IUPAC Name: (1E)-1-[Amino-(4-chloroanilino)methylidene]-2-propan-2-ylguanidine hydrochloride
The MF of Proguanil hydrochloride (CAS NO.637-32-1) is C11H17Cl2N5.
The MW of Proguanil hydrochloride (CAS NO.637-32-1) is 290.19.
Synonyms of Proguanil hydrochloride (CAS NO.637-32-1): Biguanide, 1- (p-chlorophenyl)-5-isopropyl-, monohydrochloride ; Palusil (hydrochloride) ; Diguanyl (hydrochloride)
Product Categories: Aromatics;Bases & Related Reagents;Intermediates & Fine Chemicals
Flash Point: 197.4 °C
Boiling Point: 402.7 °C
Melting Point: 249-251 °C
Apperance: White Solid
EINECS: 211-283-7
1-(p-CHLOROPHENYL)-5-ISOPROPYLBI GUANIDE HYDROCHLORIDE Uses
Proguanil hydrochloride (CAS NO.637-32-1) is used as antimalarial.
1-(p-CHLOROPHENYL)-5-ISOPROPYLBI GUANIDE HYDROCHLORIDE Toxicity Data With Reference
| 1. | orl-rat LD50:58 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 91 (1947),157. | ||
| 2. | ivn-rat LD50:33 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 91 (1947),157. | ||
| 3. | orl-mus LD50:27 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 91 (1947),157. | ||
| 4. | ivn-mus LD50:23 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 91 (1947),157. | ||
| 5. | orl-rbt LD50:172 mg/kg | BJPCAL British Journal of Pharmacology and Chemotherapy. 2 (1947),181. | ||
| 6. | ivn-rbt LD50:44,850 µg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 91 (1947),157. | ||
| 7. | ivn-gpg LD50:39,510 µg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 91 (1947),157. | ||
| 8. | orl-ckn LD50:400 mg/kg | BJPCAL British Journal of Pharmacology and Chemotherapy. 2 (1947),181. |
1-(p-CHLOROPHENYL)-5-ISOPROPYLBI GUANIDE HYDROCHLORIDE Safety Profile
Poison by ingestion and intravenous routes. Experimental reproductive effects. An antimalarial drug. When heated to decomposition it emits very toxic fumes of Cl− and NOx.Safety information of Proguanil hydrochloride (CAS NO.637-32-1):
RIDADR 3249
HazardClass 6.1(b)
PackingGroup III
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