Product Name

  • Name

    1-(2-chloroethyl)-1-nitrosourea

  • EINECS
  • CAS No. 2365-30-2
  • Article Data2
  • CAS DataBase
  • Density 1.56g/cm3
  • Solubility
  • Melting Point
  • Formula C3H6 Cl N3 O2
  • Boiling Point 241.2°Cat760mmHg
  • Molecular Weight 151.553
  • Flash Point 99.7°C
  • Transport Information
  • Appearance
  • Safety Poison by intraperitoneal and intravenous routes. Human mutation data reported. Many N-nitroso compounds are carcinogens. When heated to decomposition it emits very toxic fumes of Cl and NOx. See also N-NITROSO COMPOUNDS.
  • Risk Codes
  • Molecular Structure Molecular Structure of 2365-30-2 (1-(2-chloroethyl)-1-nitrosourea)
  • Hazard Symbols
  • Synonyms Urea,1-(2-chloroethyl)-1-nitroso- (7CI,8CI); 1-(2-Chloroethyl)-1-nitrosourea;Chloroethylnitrosourea; N-(2-Chloroethyl)-N-nitrosourea; NSC 47547
  • PSA 75.76000
  • LogP 0.98760

1-(2-CHLOROETHYL)-1-NITROSOUREA Toxicity Data With Reference

1.   

mmo-sat 1 µg/plate

    MUREAV    Mutation Research. 68 (1979),1.
2.   

mma-sat 20 nmol/plate

    CNREA8    Cancer Research. 39 (1979),1328.
3.   

dnr-esc 1 mmol/L

    CNREA8    Cancer Research. 45 (1985),6471.
4.   

dnd-hmn:ovr 50 µmol/L

    INSSDM    INSERM Symposium. 19 (1981),33.
5.   

dnd-mus:leu 10 µmol/L

    CNREA8    Cancer Research. 43 (1983),175.
6.   

msc-ham:lng 10 µmol/L

    CNREA8    Cancer Research. 40 (1980),2719.
7.   

ipr-mus LD50:4368 µg/kg

    NCISP*    National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN86 .
8.   

ivn-mus LD10:4700 µg/kg

    ANBCB3    Antibiotics and Chemotherapy. 23 (1978),64.

1-(2-CHLOROETHYL)-1-NITROSOUREA Consensus Reports

EPA Genetic Toxicology Program.

1-(2-CHLOROETHYL)-1-NITROSOUREA Safety Profile

Poison by intraperitoneal and intravenous routes. Human mutation data reported. Many N-nitroso compounds are carcinogens. When heated to decomposition it emits very toxic fumes of Cl and NOx. See also N-NITROSO COMPOUNDS.
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