Product Name

  • Name

    1-Aminopyrene

  • EINECS 216-521-3
  • CAS No. 1606-67-3
  • Article Data49
  • CAS DataBase
  • Density 1.323 g/cm3
  • Solubility Insoluble in water (0.576 mg/L at 25 deg C).
  • Melting Point 115-117 °C(lit.)
  • Formula C16H11N
  • Boiling Point 440.83 °C at 760 mmHg
  • Molecular Weight 217.27
  • Flash Point 246.207 °C
  • Transport Information
  • Appearance yellow-green powder
  • Safety 45-36/37
  • Risk Codes 22-40-21/22
  • Molecular Structure Molecular Structure of 1606-67-3 (1-Aminopyrene)
  • Hazard Symbols HarmfulXn
  • Synonyms NSC 11436;a-Aminopyrene;
  • PSA 26.02000
  • LogP 4.74740

1-Aminopyrene Chemical Properties

IUPAC Name: Pyren-1-amine
Product Name: 1-Aminopyrene
The MF of Pyren-1-amine (CAS NO.1606-67-3) is C16H11N.

                      
The MW of Pyren-1-amine (CAS NO.1606-67-3) is 217.27.
Synonyms of Pyren-1-amine (CAS NO.1606-67-3): 1-Pyrenamine ; Aminopyrene ; Pyren-1-amin ; 3-Aminopyrene ; Pyren-1-ylamine ; Pyren-1-amine
Product Categories: Aromatic Hydrocarbons (substituted) & Derivatives;Pyrenes
Stability: Stable. Incompatible with strong oxidizing agents
Appearance: yellow-green powder
Index of Refraction: 1.904 
EINECS: 216-521-3
Density: 1.322 g/ml 
Flash Point: 246.2 °C
Boiling Point: 440.8 °C
Melting Point: 116-119 °C

1-Aminopyrene Production

Raw materials: Sodium hydroxide-->Methanol-->Dichloromethane-->Thionyl chloride-->Bromine-->Ammonia-->Azabenzene-->Aluminium chloride-->Acetyl chloride-->Sodium azide-->Sodium hypochlorite-->Pyrene

1-Aminopyrene Toxicity Data With Reference

1.    

mmo-sat 500 ng/plate

    MUREAV    Mutation Research. 138 (1984),113.
2.    

dnd-esc 10 µmol/L

    PNCCA2    Proceedings, National Cancer Conference. 2 (1965),39.
3.    

orl-rat LD50:1070 mg/kg

    AIHAAP    American Industrial Hygiene Association Journal. 30 (1969),470.
4.    

ipr-mus LD50:250 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 135 (1962),376.

1-Aminopyrene Consensus Reports

Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

1-Aminopyrene Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.Safety information of Pyren-1-amine (CAS NO.1606-67-3):
Hazard Codes  HarmfulXn
Risk Statements 
40 Limited evidence of a carcinogenic effect
21/22 Harmful in contact with skin and if swallowed
Safety Statements 
45 In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
36/37 Wear suitable protective clothing and gloves
WGK Germany  3
RTECS  UR2275000

1-Aminopyrene Specification

 1-Aminopyrene neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.

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