Product Name: 1-Chloro-6,6-dimethyl-2-hepten-4-yne (CAS NO.287471-30-1)
Molecular Formula: C9H13Cl
Molecular Weight: 156.65g/mol
Mol File: 287471-30-1.mol
Appearance: Light yellow or colorless transparent liquid
Boiling point: 207.5 °C at 760 mmHg
Flash Point: 74.7 °C
Density: 0.946 g/cm3
Product Categories: Chemical intermediate for Terbinafine
Synonyms of 1-Chloro-6,6-dimethyl-2-hepten-4-yne (CAS NO.287471-30-1): 2-Hepten-4-yne, 1-Chloro-6,6-dimethyl-, (2e)- ; 1-Chloro-6,6-dimethyl-2-ene-4-yne-heptane ; 1-Chloro-6,6-dimethyl-2-hepten-4-Ino ; 2-Hepten-4-yne,1-chloro-6,6-dimethyl .
1-Chloro-6,6-dimethyl-2-hepten-4-yne (CAS NO.287471-30-1) is the allylamine antifungal agents terbinafine intermediate.
Antimicrobial effect: It choose to inhibit COX-fungal squalene, so that reduction of membrane ergosterol, thus inhibiting the growth of fungi play an inhibitory role; right ergosterol ergosterol synthesis of precursors and no inhibitory effect on other stages
Bactericidal effect: It mainly due to keratin aggregation produce squalene, was squalene cyclooxygenase inhibition, squalene in the cells of a large number gathered in the form of lipid droplets penetrate fungal cell membrane, destruction of the membrane lipid composition, resulting in fungal death .
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