-
Name
Depramine
- EINECS
- CAS No. 303-54-8
- Article Data6
- CAS DataBase
- Density 1.06g/cm3
- Solubility
- Melting Point 56-57 °C(Solv: pentane (109-66-0))
- Formula C19H22 N2
- Boiling Point 413.9°Cat760mmHg
- Molecular Weight 278.397
- Flash Point 185.9°C
- Transport Information
- Appearance
- Safety Poison by intravenous route. When heated to decomposition it emits toxic fumes of NOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms 5H-Dibenz[b,f]azepine,5-[3-(dimethylamino)propyl]- (6CI,7CI,8CI); 10,11-Dehydroimipramine;5-[3-(Dimethylamino)propyl]-5H-dibenz[b,f]azepine; Balipramine; Depramine; G31406; GP 31406
- PSA 6.48000
- LogP 4.32520
10,11-Dehydroimipramine Chemical Properties
Molecular structure of 10,11-Dehydroimipramine (CAS NO.303-54-8) is:
Product Name: 10,11-Dehydroimipramine
CAS Registry Number: 303-54-8
IUPAC Name: 3-benzo[b][1]benzazepin-11-yl-N,N-dimethylpropan-1-amine
Molecular Weight: 278.39138 [g/mol]
Molecular Formula: C19H22N2
XLogP3: 5
H-Bond Donor: 0
H-Bond Acceptor: 2
Surface Tension: 41.2 dyne/cm
Density: 1.06 g/cm3
Flash Point: 185.9 °C
Enthalpy of Vaporization: 66.67 kJ/mol
Boiling Point: 413.9 °C at 760 mmHg
Vapour Pressure: 4.64E-07 mmHg at 25°C
Related Registry Number: 58262-51-4 (hydrochloride) ; 72629-48-2 (fumarate[1:1])
10,11-Dehydroimipramine Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intravenous | 41mg/kg (41mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 120, Pg. 450, 1959. | |
| rabbit | LD50 | intravenous | 6mg/kg (6mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 120, Pg. 450, 1959. | |
| rat | LD50 | intravenous | 23mg/kg (23mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 120, Pg. 450, 1959. |
10,11-Dehydroimipramine Safety Profile
Poison by intravenous route. When heated to decomposition it emits toxic fumes of NOx.
10,11-Dehydroimipramine Specification
10,11-Dehydroimipramine , its cas register number is 303-54-8. It also can be called Depramine [INN] ; 10,11-Dehydroimipramine ; 5-(3-(Dimethylamino)propyl)-5H-dibenz(b,f)azepine ; 5-20-08-00247 (Beilstein Handbook Reference) ; BRN 1319717 ; Balipramine ; Depramina ; Depramina [INN-Spanish] ; Depramine ; Depraminum ; Depraminum [INN-Latin] ; GP 31406 ; UNII-77C3T28736 ; 5-(3-(Dimethylamino)propyl)-5H-dibenz(b,f)azepine ; 5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)propyl)- ; 5H-Dibenz(b,f)azepine-5-propanamine, N,N-dimethyl- (9CI) .
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