2-(Ethylamino)ethanol supplier

Name
2-(Ethylamino)ethanol
EINECS 203-797-5
CAS No. 110-73-6
Article Data35
CAS DataBase
Density 0.883 g/cm³
Solubility miscible with water
Melting Point -6 °C
Formula C₄H₁₁NO
Boiling Point 169.5 °C at 760 mmHg
Molecular Weight 89.1374
Flash Point 71.1 °C
Transport Information UN 2810 6.1/PG 3
Appearance Clear colorless to slightly yellowish liquid
Safety 26-36/37/39-45-36
Risk Codes 22-24-41-34
Molecular Structure
Hazard Symbols T
Synonyms (2-Hydroxyethyl)ethylamine;2-(Monoethylamino)ethanol;2-(N-Ethylamino)ethanol;Amino Alcohol MEM;N-(2-Hydroxyethyl)ethylamine;N-Ethyl-2-aminoethanol;N-Ethyl-N-(2-hydroxyethyl)amine;N-Ethyl-N-(b-hydroxyethyl)amine;N-Ethylethanolamine;N-Ethylmonoethanolamine;
PSA 32.26000
LogP -0.02090

Synthetic route

: 75-21-8
oxirane

: 75-04-7
ethylamine

: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
In water at 35℃; for 0.0444444h; Temperature;	94%
In ethanol; water at 30 - 40℃;	45%

: 100-37-8
2-(Diethylamino)ethanol

A: 50-00-0
formaldehyd

B: 75-04-7
ethylamine

C: 75-07-0
acetaldehyde

D: 109-89-7
diethylamine

E: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
With water at 25℃; Product distribution; Mechanism; anodic oxidation, carbonate buffer, pH 10; effect of substituents investigated with different types of β-alkanolamines;	A 5% B 1.6% C 72% D 20% E 73%

...Expand

: 100-37-8
2-(Diethylamino)ethanol

A: 50-00-0
formaldehyd

B: 75-07-0
acetaldehyde

C: 109-89-7
diethylamine

D: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
With water at 25℃; anodic oxidation, pH 10, carbonate buffer; Further byproducts given;	A 5% B 72% C 20% D 73%

...Expand

: 1120-64-5
2-methyl-4,5-dihydro-1,3-oxazole

: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
With platinum on carbon; hydrogen at 25℃; under 30003 Torr; for 16h; Autoclave;	60%

: 1120-64-5
2-methyl-4,5-dihydro-1,3-oxazole

A: 110-73-6
2-(Ethylamino)ethanol

B: 100-37-8
2-(Diethylamino)ethanol

Conditions

Conditions	Yield
With platinum on carbon; hydrogen at 25℃; under 7500.75 Torr; for 16h;	A 60% B 19%

: 139-87-7
ethyldiethanolamine

: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
With ethylamine In water at 350℃; for 2h; Temperature; Reagent/catalyst; Solvent;	49.9%
With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; caesium carbonate; ethylamine In water at 150℃; for 12h; Catalytic behavior; Reagent/catalyst; Temperature; Inert atmosphere;

: 2-(N-ethyltritylamino)ethanol

: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
Stage #1: 2-(N-ethyltritylamino)ethanol With n-butyllithium In hexane at 0℃; Stage #2: With naphthalene; lithium In tetrahydrofuran; hexane at 0℃; for 4.5h; Stage #3: With water In tetrahydrofuran; hexane at 0 - 20℃;	41%

: 75-21-8
oxirane

: 75-04-7
ethylamine

A: 139-87-7
ethyldiethanolamine

B: 110-73-6
2-(Ethylamino)ethanol

...Expand

: 110-86-1
pyridine

: 100-37-8
2-(Diethylamino)ethanol

: 94-36-0
dibenzoyl peroxide

A: 75-07-0
acetaldehyde

B: 109-89-7
diethylamine

C: 110-73-6
2-(Ethylamino)ethanol

...Expand

: 98069-33-1
ethyl-carbamic acid-(2-chloro-ethyl ester)

: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
With sodium hydroxide und nachfolgendes Erwaermen auf 80-90grad;

: 141-43-5
ethanolamine

: 106-93-4
ethylene dibromide

: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
at 50 - 60℃;

: 543-24-8
N-acetylglycine

: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
With tetrahydrofuran; lithium aluminium tetrahydride

: 371-38-0
N-(2-hydroxyethyl)fluoroacetamide

: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In tetrahydrofuran Heating;

: 21010-46-8
N-ethyl-N-(2-chloro-ethyl)-benzamide

: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
With sodium hydroxide Heating;

: 16250-70-7
2-methyl-2,3,4,5-tetrahydroisoxazole

: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
With sodium tetrahydroborate In ethanol at 0℃; for 0.0833333h; Yield given;

: 108-24-7
acetic anhydride

: 141-43-5
ethanolamine

: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride 1.) pyridine, 2 h, r. t., 2.) THF; Multistep reaction;

: 17886-23-6
1-ethyl-4,5-dihydro-1H-[1,2,3]triazole

A: 1072-45-3
N-ethylaziridine

B: 75-04-7
ethylamine

C: 75-07-0
acetaldehyde

D: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
With water at 25℃; Rate constant; Mechanism; pH 10.75 (lysine buffer); other pH (other buffer concentration), H/D isotope effect;

...Expand

2--benzoic acid: 2--benzoic acid

: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
With hydrogenchloride

N-ethyl-N-<2-hydroxy-ethyl>-aniline: N-ethyl-N-<2-hydroxy-ethyl>-aniline

: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
With hydrogenchloride; sodium nitrite durch Erhitzen des gebildeten, nicht naeher beschribenen N-Aethyl-N-<2-hydroxy-aethyl>-4-nitroso-anilins mit 50prozentig. NaOH;

: 98069-33-1
ethyl-carbamic acid-(2-chloro-ethyl ester)

aqueous alcoholic NaOH-solution: aqueous alcoholic NaOH-solution

: 110-73-6
2-(Ethylamino)ethanol

: 391912-69-9
[4-(4-Bromo-butoxy)-phenyl]-methyl-carbamic acid 4-chloro-phenyl ester

A: (4-{4-[Ethyl-(2-hydroxy-ethyl)-amino]-butoxy}-phenyl)-methyl-carbamic acid 4-chloro-phenyl ester

B: 110-73-6
2-(Ethylamino)ethanol

: 64-17-5
ethanol

: 141-43-5
ethanolamine

: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
With mesoporous Cs-B-Zr mixed oxide In neat (no solvent) at 220℃; under 32253.2 Torr; for 0.5h; Autoclave; Inert atmosphere; Green chemistry;

: 74-96-4
ethyl bromide

: 141-43-5
ethanolamine

: 110-73-6
2-(Ethylamino)ethanol

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 3h;

: 15159-40-7
4-morpholinocarbonyl chloride

: 110-73-6
2-(Ethylamino)ethanol

: 72275-32-2
N-ethyl-N-(2-hydroxyethyl)-4-morpholinecarboxamide

Conditions

Conditions	Yield
In benzene for 0.5h;	100%

: 6704-31-0
oxetan-3-one

: 110-73-6
2-(Ethylamino)ethanol

: 8-ethyl-2,5-dioxa-8-azaspiro[3.4]octane

Conditions

Conditions	Yield
With acetic acid In dichloromethane at 20℃; Molecular sieve; Inert atmosphere;	99%

: 106-99-0
buta-1,3-diene

: 110-73-6
2-(Ethylamino)ethanol

A: 86905-89-7
N-ethyl-N(2,7-octadienyl)-2 amino ethanol

B: 68165-92-4
N-ethyl-N(1,7octadien-3-yl)-2 amino ethanol

Conditions

Conditions	Yield
Pd(acac)2*2PPh3 at 80℃; under 3800 Torr; for 16h;	A 98.5% B 1.5%

...Expand

: 100-52-7
benzaldehyde

: 110-73-6
2-(Ethylamino)ethanol

: 1741-81-7
3-ethyl-2-phenyl-1,3-oxazolidine

Conditions

Conditions	Yield
In benzene Heating;	98%

: 104-88-1
4-chlorobenzaldehyde

: 110-73-6
2-(Ethylamino)ethanol

: 19394-03-7
2-(4-chloro-phenyl)-3-ethyl-oxazolidine

Conditions

Conditions	Yield
In benzene Heating;	98%
In benzene Heating;

: 555-16-8
4-nitrobenzaldehdye

: 110-73-6
2-(Ethylamino)ethanol

: 19394-04-8
3-ethyl-2-(4-nitro-phenyl)-oxazolidine

Conditions

Conditions	Yield
In benzene Heating;	98%
In benzene Heating;

: 104-87-0
4-methyl-benzaldehyde

: 110-73-6
2-(Ethylamino)ethanol

: 19394-02-6
3-ethyl-2-p-tolyl-oxazolidine

Conditions

Conditions	Yield
In benzene Heating;	98%

: 876-08-4
p-(chloromethyl)benzoyl chloride

: 110-73-6
2-(Ethylamino)ethanol

: 948877-06-3
N-ethyl-N-(2-hydroxyethyl)-4-(chloromethyl)benzamide

Conditions

Conditions	Yield
In tetrahydrofuran at 0 - 20℃; for 4h;	98%

: 110-73-6
2-(Ethylamino)ethanol

: 948553-53-5
7-chloro-3-(2,4-dichlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidine

: 2-((3-(2,4-dichlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl)(ethyl)amino)ethanol

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In acetonitrile for 3.5h; Reflux; Inert atmosphere;	98%

: 5462-86-2
6-chloro-9-ethyl-9H-purine

: 110-73-6
2-(Ethylamino)ethanol

: N6,9-diethyl-N6-(2-hydroxyethyl)adenine

Conditions

Conditions	Yield
In butan-1-ol for 0.75h; Heating;	97%

: 1126-93-8
2-ethoxy-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

: 110-73-6
2-(Ethylamino)ethanol

: 78466-15-6
C2(CH3)4O2BOCH2CH2NHCH2CH3

Conditions

Conditions	Yield
In benzene byproducts: ethanol; amine added to B compd., benzene added, shaken and refluxed for 2 h, moisture excluded; EtOH-benzene distd. azeotropically, solvent evapd. in vac. at room temp., distd.; elem. anal.;	97%

: 1885-14-9
phenyl chloroformate

: 110-73-6
2-(Ethylamino)ethanol

: 67249-24-5
benzyl N-ethyl N-(2-hydroxyethyl) carbamate

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 25℃;	97%

: 24424-99-5
di-tert-butyl dicarbonate

: 110-73-6
2-(Ethylamino)ethanol

: 152192-95-5
tert-butyl N-ethyl-N-(2-hydroxyethyl)carbamate

Conditions

Conditions	Yield
In dichloromethane for 24h; Ambient temperature;	96%
In dichloromethane at 20℃; for 14h; Cooling with ice;	95%
With triethylamine In dichloromethane at 20℃; for 16h;	40.7%

: 1041598-53-1
4-fluoro-N-methyl-3-nitrobenzenesulfonamide

: 110-73-6
2-(Ethylamino)ethanol

: 1351094-15-9
4-[ethyl(2-hydroxyethyl)amino]-N-methyl-3-nitrobenzenesulfonamide

Conditions

Conditions	Yield
With silver trifluoromethanesulfonate at 110℃; for 18h; Sealed tube; Microwave irradiation;	96%

: 110-73-6
2-(Ethylamino)ethanol

: 140-88-5
ethyl acrylate

: 144205-55-0
N,N-2-hydroxyethyl-2-carbethoxyethylethylamine

Conditions

Conditions	Yield
for 12h; Ambient temperature;	95%
at 20℃; for 48h;	81%

: 556-61-6
methyl thioisocyanate

: 110-73-6
2-(Ethylamino)ethanol

: 1-ethyl-1-(2-hydroxy-ethyl)-3-methyl-thiourea

Conditions

Conditions	Yield
In tetrahydrofuran Ambient temperature;	95%

: 75-15-0
carbon disulfide

: 110-73-6
2-(Ethylamino)ethanol

: 74-88-4
methyl iodide

: ethyl-(2-hydroxy-ethyl)-dithiocarbamic acid methyl ester

Conditions

Conditions	Yield
With tetra-(n-butyl)ammonium iodide; caesium carbonate In N,N-dimethyl-formamide at 0 - 20℃; for 0.25h;	95%

...Expand

: 5891-21-4
5-chloro-2-pentanone

: 110-73-6
2-(Ethylamino)ethanol

: 74509-79-8
5-(N-ethyl-N-2-hydroxyethylamine)-2-pentanone

Conditions

Conditions	Yield
With tetrabutylammomium bromide; potassium hydroxide In chloroform; water at 20 - 30℃; for 3h;	94.7%
With sodium chloride; xylene

: 75-15-0
carbon disulfide

: 110-73-6
2-(Ethylamino)ethanol

: benzyl-(2-bromo-ethyl)-butyl-amine

: ethyl-(2-hydroxy-ethyl)-dithiocarbamic acid 2-(benzyl-butyl-amino)-ethyl ester

Conditions

Conditions	Yield
With tetra-(n-butyl)ammonium iodide; caesium carbonate In N,N-dimethyl-formamide at 0 - 20℃; for 1h;	94%

...Expand

: 75-15-0
carbon disulfide

: 105-76-0
Dibutyl maleate

: 110-73-6
2-(Ethylamino)ethanol

: 885700-65-2
C17H31NO5S2

Conditions

Conditions	Yield
at 70℃; for 6.66667h;	94%

...Expand

: 1044579-39-6
4-[(4-dimethylamino)phenylazo]benzoyl-1H-benzotriazole

: 110-73-6
2-(Ethylamino)ethanol

: 1044579-53-4
C19H24N4O2

Conditions

Conditions	Yield
In tetrahydrofuran at 20℃;	94%

: 110-73-6
2-(Ethylamino)ethanol

: 4535-87-9
N-(2-chloroethyl)ethylamine hydrochloride

Conditions

Conditions	Yield
With thionyl chloride In chloroform for 6h; Heating;	93%
With thionyl chloride In chloroform Heating;
With thionyl chloride In toluene

: 54231-35-5
3-fuoro-2-nitropyridine

: 110-73-6
2-(Ethylamino)ethanol

: 1-ethyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine

Conditions

Conditions	Yield
With lithium hydride In dimethyl sulfoxide at 110℃; for 1.5h;	93%

: 110-73-6
2-(Ethylamino)ethanol

: ethyl 3-hydroxy-2-(2,4-dinitrophenyl)-2-butenoate

: 15568-56-6
N-ethyl-N-(2-hydroxyethyl)ethanamide

Conditions

Conditions	Yield
In chloroform at 20℃; for 120h; Temperature; chemoselective reaction;	93%

: phenyl (4-methoxybenzoyl)oxycarbamate

: 110-73-6
2-(Ethylamino)ethanol

: 1-ethyl-1-(2-hydroxyethyl)-3-((4-methoxybenzoyl)oxy)urea

Conditions

Conditions	Yield
With 1H-imidazole In tetrahydrofuran at 100℃; for 2h; Microwave irradiation; Sealed tube;	93%

: 1514-50-7
4-iodobenzenediazonium tetrafluoroborate

: 110-73-6
2-(Ethylamino)ethanol

: 1-(4-iodophenyl)-3-(2-hydroxyethyl)-3-ethyltriazene

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide for 1h;	92%

: [4-(3-bromo-propoxy)-cyclohexyl]-methyl-carbamic acid tert-butyl ester

: 110-73-6
2-(Ethylamino)ethanol

: (4-{3-[ethyl-(2-hydroxy-ethyl)-amino]-propoxy}-cyclohexyl)-methyl-carbamic acid tert-butyl ester

Conditions

Conditions	Yield
In N,N-dimethyl acetamide at 20℃;	92%

: 38565-53-6
(2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-heptadecafluorononyl)oxirane

: 110-73-6
2-(Ethylamino)ethanol

: 1-[ethyl-(2-hydroxy-ethyl)-amino]-4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecan-2-ol

Conditions

Conditions	Yield
at 85℃; for 3h;	92%

: 110-73-6
2-(Ethylamino)ethanol

: 1131-01-7
2-chloro-N-(2,6-dimethylphenyl)acetamide

: 20846-29-1
2-(N-Ethyl-2-hydroxyethylamino)-2',6'-dimethyl-acetanilid

Conditions

Conditions	Yield
at 20℃;	92%

2-(Ethylamino)ethanol Chemical Properties

IUPAC Name: 2-(Ethylamino)ethanol
The MF of 2-(Ethylamino)ethanol (110-73-6) is C₄H₁₁NO.

The MW of 2-(Ethylamino)ethanol (110-73-6) is 89.14.
Synonyms of 2-(Ethylamino)ethanol (110-73-6): (2-Hydroxyethyl)ethylamine ; 2-(Ethylamino)-ethano ; 2-Ethylamino-1-ethanol ; 2-N-Monoethylaminoethanol ; Ethyl-2-hydroxyethylamine ; Monoethylaminoethanol ; Ethylaminoethanol,[combustibleliquidlabel]
Product Categories: Alkohols
Form: Clear colorless to slightly yellowish liquid
Index of Refraction: 1.423
EINECS: 203-797-5
Density: 0.883 g/ml
Flash Point: 71.1 °C
Boiling Point: 169.5 °C
Melting Point: -90 °C
Water Solubility: miscible
BRN: 635671

2-(Ethylamino)ethanol Production

It is an aminoalcohol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

2-(Ethylamino)ethanol Toxicity Data With Reference

1.	skn-rbt 10 mg/24H open MLD	AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. 10 (1954),61.
2.	eye-rbt 250 µg open SEV	AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. 10 (1954),61.
3.	orl-rat LD50:1000 mg/kg	FCTXAV Food and Cosmetics Toxicology. 5 (1967),327.
4.	ipr-rat LD50:1170 mg/kg	TXAPA9 Toxicology and Applied Pharmacology. 12 (1968),486.
5.	skn-rbt LD50:360 mg/kg	AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. 10 (1954),61.
6.	orl-mam LD50:1200 mg/kg	TXAPA9 Toxicology and Applied Pharmacology. 8 (1966),344.

2-(Ethylamino)ethanol Consensus Reports

Reported in EPA TSCA Inventory.

2-(Ethylamino)ethanol Safety Profile

Poison by skin contact. Moderately toxic by ingestion and intraperitoneal routes. A skin and severe eye irritant. Flammable when exposed to heat or flame; can react vigorously with oxidizers. To fight fire, use alcohol foam, dry chemical, CO₂. When heated to decomposition it emits toxic fumes of NO_x.
Safety information of 2-(Ethylamino)ethanol (110-73-6):
Hazard Codes T
Risk Statements
22 Harmful if swallowed
24 Toxic in contact with skin
41 Risk of serious damage to eyes
34 Causes burns
Safety Statements
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39 Wear suitable protective clothing, gloves and eye/face protection
45 In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR UN 2810 6.1/PG 3
WGK Germany 1
RTECS KK9100000
HazardClass 8
PackingGroup III
HS Code 29221980

2-(Ethylamino)ethanol Specification

A colorless liquid with an amine-like odor. Flash point 160°F. Slightly less dense than water. May mildly irritate skin and eyes. At high temperature may decompose to yield toxic oxides of nitrogen.

Product Name

2-(Ethylamino)ethanol

Synthetic route

2-(Ethylamino)ethanol Chemical Properties

2-(Ethylamino)ethanol Production

2-(Ethylamino)ethanol Toxicity Data With Reference

2-(Ethylamino)ethanol Consensus Reports

2-(Ethylamino)ethanol Safety Profile

2-(Ethylamino)ethanol Specification

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