PENTAFLUOROPROPIONAMIDE

The 2,2,3,3,3-Pentafluoropropanamide with its cas register number is 354-76-7. It also can be called as Propanamide, 2,2,3,3,3-pentafluoro-  and the IUPAC Name about this chemical is 2,2,3,3,3-pentafluoropropanamide.

Physical properties about 2,2,3,3,3-Pentafluoropropanamide are: (1)ACD/LogP: 1.75; (2)ACD/LogD (pH 5.5): 1.75; (3)ACD/LogD (pH 7.4): 1.75; (4)ACD/BCF (pH 5.5): 12.53; (5)ACD/BCF (pH 7.4): 12.53; (6)ACD/KOC (pH 5.5): 212.61; (7)ACD/KOC (pH 7.4): 212.61; (8)#H bond acceptors: 2; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 1; (11)Polar Surface Area: 20.31Ų; (12)Index of Refraction: 1.306; (13)Molar Refractivity: 20.26 cm³; (14)Molar Volume: 106.1 cm³; (15)Polarizability: 8.03x10^-24cm³; (16)Surface Tension: 19.5 dyne/cm; (17)Enthalpy of Vaporization: 39.39 kJ/mol; (18)Vapour Pressure: 2.79 mmHg at 25°C

Preparation: this chemical can be prepared by 2-bromoundecafluoro-2-methyl-3-pentanone, also this reaction can produce 2-bromo-1,1,1,3,3,3-hexafluoro-propane. This reaction will need reagent diethyl ether and liquid ammonia. The yield is about 83%.

Uses of 2,2,3,3,3-Pentafluoropropanamide: it can be used to produce 2,2,3,3,3-pentafluoro-N-[2,2,2-trifluoro-1-(2,2,2-trifluoro-acetylamino)-1-trifluoromethyl-ethyl]-propionamide with hexafluoroacetone trifluoroacetylimine at temperature of 100 - 150 ℃. The reaction time needs 3 hour(s). The yield is about 92%.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. When you are using it, wear suitable protective clothing. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C(=O)(C(C(F)(F)F)(F)F)N
(2)InChI: InChI=1S/C3H2F5NO/c4-2(5,1(9)10)3(6,7)8/h(H2,9,10)
(3)InChIKey: KQTOYEUYHXUEDB-UHFFFAOYSA-N