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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid

Cas:35480-52-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2,5-Bis-(2,2,2-Trifluoroethoxy)Benzoic Acid supplier in China

Cas:35480-52-5

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product description: Product name 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid CAS number 35480-52-5 Assay ≥99% Appearance White crystalline powder Capacity 200mt/year Applicatio

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid

Cas:35480-52-5

Min.Order:10 Gram

FOB Price: $12.0

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid

Cas:35480-52-5

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2,5-Bis-(2,2,2-trifluoroethoxy)-benzoic acid

Cas:35480-52-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFU CHEM--2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid

Cas:35480-52-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

GMP factory supplyCAS 35480-52-5 with fast shipping

Cas:35480-52-5

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product Name 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid Apperance White powder EINECS N/A MF

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid

Cas:35480-52-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:Yellowish liquid Storage:R.T Package:25kg/Barrel Application:Flecainide Intermediate Transportation:Express/Sea/Air Port:Any port in China

Flecainide Intermediate 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid cas 35480-52-5

Cas:35480-52-5

Min.Order:5 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzoic acid,2,5-bis(2,2,2-trifluoroethoxy)- 35480-52-5

Cas:35480-52-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid CAS: 35480-52-5 MF: C11H8F6O4 MW: 318.17 EINECS: 206-577-7 Mol File: 35480-52-5.mol 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid Structure 2,5-Bis(2,2,2-trifluoroethoxy)benzoi

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid

Cas:35480-52-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid CAS:35480-52-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in hig

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid CAS:35480-52-5

Cas:35480-52-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzoic acid,2,5-bis(2,2,2-trifluoroethoxy)-

Cas:35480-52-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid

Cas:35480-52-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzoic acid,2,5-bis(2,2,2-trifluoroethoxy)-

Cas:35480-52-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid

Cas:35480-52-5

Min.Order:1 Kilogram

FOB Price: $10.0 / 100.0

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2,5-Bis(2,2,2-Trifluoroethoxy)Benzoic Acid

Cas:35480-52-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Hangzhou Yunuo Chemical Co., Ltd is located in Hangzhou city China. As a global supplier in the chemical industry, Yunuochem is to create added value for customers around the world. Sticking to such business idea of "Good faith wins the business

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid

Cas:35480-52-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid

Cas:35480-52-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

2,5-BIS(2,2,2-TRIFLUOROETHOXY)BENZOIC ACID 35480-52-5

Cas:35480-52-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Hope Chem Co., Ltd

1. Product advantages: exquisite appearance and unique functions. 2. Product Advantages: Our products are the best,fast speed ,in large stock 3. High-quality products and thoughtful service are your greatest satisfaction. 4. The product

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid

Cas:35480-52-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2,5-Bis(2,2,2-Trifluoroethoxy)Benzoic Acid

Cas:35480-52-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and als

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid

Cas:35480-52-5

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2,5-Bis-(2,2,2-Trifluoroethoxy)Benzoic Acid

Cas:35480-52-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid

Cas:35480-52-5

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 2,5-Bis-(2,2,2-Trifluoroethoxy)Benzoic Acid CAS No.:35480-52-5 Molecule Formula:C11H8F6O4 Molecule Weight:318.17 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Stan

High Quality 2,5-Bis-(2,2,2-Trifluoroethoxy)Benzoic Acid on stock

Cas:35480-52-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid

Cas:35480-52-5

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid

Cas:35480-52-5

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid

Cas:35480-52-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2,2,2-trifluoroethanol
75-89-8

2,2,2-trifluoroethanol

5-bromo-2-chlorobenzoic acid
21739-92-4

5-bromo-2-chlorobenzoic acid

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

Conditions
ConditionsYield
With C10H12N2O8(4-)*Cu(2+)*2H4N(1+) In N,N-dimethyl-formamide at 20℃; for 4h; Reagent/catalyst;93.5%
With potassium tert-butylate; copper(I) bromide In tetrahydrofuran; water45%
methyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate
35480-31-0

methyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

Conditions
ConditionsYield
With sodium hydroxide In water for 20h; Reflux;92%
1-[2,5-bis(2,2,2-trifluoroethoxy)phenyl]ethanone

1-[2,5-bis(2,2,2-trifluoroethoxy)phenyl]ethanone

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

Conditions
ConditionsYield
With sodium hypochlorite; sodium hydroxide In water at 95℃; for 9h; Sealed tube;89%
With sodium hypochlorite In 1,4-dioxane at 35℃; for 3h;
2,5-bis(2,2,2-trifluroethoxy)toluene
1023951-32-7

2,5-bis(2,2,2-trifluroethoxy)toluene

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

Conditions
ConditionsYield
Stage #1: 2,5-bis(2,2,2-trifluroethoxy)toluene With pyridine; sodium hydroxide; copper(II) sulfate In water at 18 - 81℃; for 1h;
Stage #2: With sodium permanganate In water at 81 - 93℃; for 7.75h;
Stage #3: With hydrogenchloride In water pH=1 - 2; Product distribution / selectivity;
81.6%
Stage #1: 2,5-bis(2,2,2-trifluroethoxy)toluene With pyridine; sodium hydroxide; potassium permanganate In water at 85 - 100℃; for 1h; pH=11 - 12;
Stage #2: With hydrogenchloride In water pH=1 - 2; Product distribution / selectivity;
75.2%
5-bromo-2-(2,2,2-trifluoroethoxy)benzoic acid

5-bromo-2-(2,2,2-trifluoroethoxy)benzoic acid

2,2,2-trifluoroethanol
75-89-8

2,2,2-trifluoroethanol

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

Conditions
ConditionsYield
Stage #1: 2,2,2-trifluoroethanol With sodium t-butanolate In DMF (N,N-dimethyl-formamide) at 0 - 25℃; for 1h;
Stage #2: 5-bromo-2-(2,2,2-trifluoroethoxy)benzoic acid; copper(I) bromide In DMF (N,N-dimethyl-formamide) at 100℃; for 10h;
75.3%
1.4-dibromobenzene
106-37-6

1.4-dibromobenzene

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sodium / 1,4-dioxane
1.2: 6 h / 110 °C / Autoclave
2.1: aluminum (III) chloride / dichloromethane / 6 h / 0 - 20 °C
3.1: sodium hydroxide; sodium hypochlorite / water / 9 h / 95 °C / Sealed tube
View Scheme
Multi-step reaction with 3 steps
1: sodium t-butanolate / N,N-dimethyl-formamide / 4 h / 20 °C / Autoclave; Large scale
2: aluminum (III) chloride / dichloromethane / 0.67 h / 20 °C
3: sodium hypochlorite / 1,4-dioxane / 3 h / 35 °C
View Scheme
Methyl 2,5-dihydroxybenzoate
2150-46-1

Methyl 2,5-dihydroxybenzoate

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium carbonate / acetone / 31 h / Reflux
2: sodium hydroxide / water / 20 h / Reflux
View Scheme
methanol
67-56-1

methanol

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

methyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate
35480-31-0

methyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate

Conditions
ConditionsYield
With thionyl chloride at 80℃; for 2h;98%
With thionyl chloride Heating;
formaldehyd
50-00-0

formaldehyd

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

4,7-bis(2,2,2-trifluoroethoxy)-2,3-dihydro-1H-inden-1-one

4,7-bis(2,2,2-trifluoroethoxy)-2,3-dihydro-1H-inden-1-one

Conditions
ConditionsYield
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium acetate at 160℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;71%
2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

2,5-bis(2,2,2-trifluoroethoxy)benzoic acid chloride
50778-59-1

2,5-bis(2,2,2-trifluoroethoxy)benzoic acid chloride

Conditions
ConditionsYield
In benzene
With oxalyl dichloride In dichloromethane at 20℃; for 21h; Inert atmosphere;
In N-methyl-acetamide; water; benzene
2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

chloroformic acid ethyl ester
541-41-3

chloroformic acid ethyl ester

C14H12F6O6

C14H12F6O6

Conditions
ConditionsYield
With triethylamine In ethyl acetate at 5 - 10℃; for 0.5h;
(2-aminomethylpyridine)
3731-51-9

(2-aminomethylpyridine)

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

2,5-bis(2,2,2-trifluoroethoxy)-N-(pyridin-2-ylmethyl)-benzamide
57415-36-8

2,5-bis(2,2,2-trifluoroethoxy)-N-(pyridin-2-ylmethyl)-benzamide

Conditions
ConditionsYield
Stage #1: 2,5-di-(2,2,2-trifluoroethoxy)benzoic acid With pivaloyl chloride; triethylamine In dichloromethane; N,N-dimethyl acetamide at -30 - -20℃;
Stage #2: 2-(Aminomethyl)pyridine In dichloromethane; N,N-dimethyl acetamide at -20℃; for 2h;
Stage #3: With sodium carbonate In dichloromethane; N,N-dimethyl acetamide; water Product distribution / selectivity;
Stage #1: 2,5-di-(2,2,2-trifluoroethoxy)benzoic acid With chloroformic acid ethyl ester; triethylamine In dichloromethane; N,N-dimethyl acetamide at -30 - -20℃;
Stage #2: 2-(Aminomethyl)pyridine In dichloromethane; N,N-dimethyl acetamide at -20℃; for 2h;
Stage #3: With sodium carbonate In dichloromethane; N,N-dimethyl acetamide; water Product distribution / selectivity;
Stage #1: 2,5-di-(2,2,2-trifluoroethoxy)benzoic acid With pivaloyl chloride; triethylamine In dichloromethane; N,N-dimethyl-formamide at -30 - -20℃;
Stage #2: 2-(Aminomethyl)pyridine In dichloromethane; N,N-dimethyl acetamide at -20℃; for 2h;
Stage #3: With sodium carbonate In dichloromethane; water; N,N-dimethyl-formamide Product distribution / selectivity;
Stage #1: 2,5-di-(2,2,2-trifluoroethoxy)benzoic acid With 4-methyl-morpholine; pivaloyl chloride In dichloromethane; N,N-dimethyl acetamide at -30 - -20℃;
Stage #2: 2-(Aminomethyl)pyridine In dichloromethane; N,N-dimethyl acetamide at -20℃; for 2h;
Stage #3: With sodium carbonate In dichloromethane; N,N-dimethyl acetamide; water Product distribution / selectivity;
2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

2-(2,5-bis (2,2,2-trifluoroethoxy)phenyl)-5-(benzylthio)-1,3,4-oxadiazole

2-(2,5-bis (2,2,2-trifluoroethoxy)phenyl)-5-(benzylthio)-1,3,4-oxadiazole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: thionyl chloride / Heating
2.1: hydrazine hydrate / Heating
3.1: potassium hydroxide / methanol / 0.17 h / 10 - 15 °C
3.2: Reflux
4.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C
View Scheme
2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

2-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-5-(allyl thio)-1,3,4-oxadiazole

2-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-5-(allyl thio)-1,3,4-oxadiazole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: thionyl chloride / Heating
2.1: hydrazine hydrate / Heating
3.1: potassium hydroxide / methanol / 0.17 h / 10 - 15 °C
3.2: Reflux
4.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C
View Scheme
2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

2-(5-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-1,3,4-oxadiazol-2-ylthio)-1-(2,7-dichloro-9H-fluoren-4-yl) ethanone

2-(5-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-1,3,4-oxadiazol-2-ylthio)-1-(2,7-dichloro-9H-fluoren-4-yl) ethanone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: thionyl chloride / Heating
2.1: hydrazine hydrate / Heating
3.1: potassium hydroxide / methanol / 0.17 h / 10 - 15 °C
3.2: Reflux
4.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C
View Scheme
2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid hydrazide
50778-75-1

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid hydrazide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: thionyl chloride / Heating
2: hydrazine hydrate / Heating
View Scheme
2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

5-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-1,3,4-oxadiazole-2-thiol

5-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-1,3,4-oxadiazole-2-thiol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: thionyl chloride / Heating
2.1: hydrazine hydrate / Heating
3.1: potassium hydroxide / methanol / 0.17 h / 10 - 15 °C
3.2: Reflux
View Scheme
2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

2-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-5-(4-nitrobenzylthio)-1,3,4-oxadiazole

2-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-5-(4-nitrobenzylthio)-1,3,4-oxadiazole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: thionyl chloride / Heating
2.1: hydrazine hydrate / Heating
3.1: potassium hydroxide / methanol / 0.17 h / 10 - 15 °C
3.2: Reflux
4.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C
View Scheme
2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

2-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-5-(methyl thio)-1,3,4-oxadiazole

2-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-5-(methyl thio)-1,3,4-oxadiazole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: thionyl chloride / Heating
2.1: hydrazine hydrate / Heating
3.1: potassium hydroxide / methanol / 0.17 h / 10 - 15 °C
3.2: Reflux
4.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C
View Scheme
2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

2-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-5-(2-methylbenzylthio)-1,3,4-oxadiazole

2-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-5-(2-methylbenzylthio)-1,3,4-oxadiazole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: thionyl chloride / Heating
2.1: hydrazine hydrate / Heating
3.1: potassium hydroxide / methanol / 0.17 h / 10 - 15 °C
3.2: Reflux
4.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C
View Scheme
2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

2-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-5-(2-chlorobenzylthio)-1,3,4-oxadiazole

2-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-5-(2-chlorobenzylthio)-1,3,4-oxadiazole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: thionyl chloride / Heating
2.1: hydrazine hydrate / Heating
3.1: potassium hydroxide / methanol / 0.17 h / 10 - 15 °C
3.2: Reflux
4.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C
View Scheme
2,5-di-(2,2,2-trifluoroethoxy)benzoic acid
35480-52-5

2,5-di-(2,2,2-trifluoroethoxy)benzoic acid

2-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-5-(ethylthio)-1,3,4-oxadiazole

2-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-5-(ethylthio)-1,3,4-oxadiazole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: thionyl chloride / Heating
2.1: hydrazine hydrate / Heating
3.1: potassium hydroxide / methanol / 0.17 h / 10 - 15 °C
3.2: Reflux
4.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C
View Scheme

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