• Name

  IFLAB-BB F1963-0009

• EINECS
• CAS No. 32091-51-3
• Article Data13
• CAS DataBase
• Density 1.4 g/cm³
• Solubility
• Melting Point 108 °C
• Formula C₃H₃NOS
• Boiling Point 123.6 °C at 760 mmHg
• Molecular Weight 101.129
• Flash Point 28.6 °C
• Transport Information
• Appearance
• Safety
• Risk Codes
• Molecular Structure
• Hazard Symbols
• Synonyms IFLAB-BB F1963-0009;3H-OXAZOLE-2-THIONE;2-mercaptooxazole;2(3H)-Oxazolethione
• PSA 61.02000
• LogP 1.33720

Synthetic route

463-56-9

thiocyanic acid

621-63-6

glycoaldehyde diethyl acetal

32091-51-3

2-mercapto-1,3-oxazole

Conditions

Conditions	Yield
In acetonitrile for 4h; Heating;	100%

333-20-0

potassium thioacyanate

621-63-6

glycoaldehyde diethyl acetal

32091-51-3

2-mercapto-1,3-oxazole

Conditions

Conditions	Yield
Stage #1: potassium thioacyanate With hydrogenchloride In acetonitrile at 20℃; for 0.5h; Inert atmosphere; Stage #2: glycoaldehyde diethyl acetal In acetonitrile for 4h; Reflux;	86%

133-38-0

dihydroxyfumaric acid

141-46-8

Glycolaldehyde

32091-51-3

2-mercapto-1,3-oxazole

Conditions

Conditions	Yield
With hydrogenchloride In ethanol; water	30.8%

23147-58-2, 110822-84-9, 110822-85-0

glycolaldehyde dimer

463-56-9

thiocyanic acid

32091-51-3

2-mercapto-1,3-oxazole

Conditions

Conditions	Yield
for 4h; Heating / reflux;

4704-60-3

cephalosporanic acid

32510-61-5

7-((tetrazol-1'-yl)acetylamino)-3-acetyloxymethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

32091-51-3

2-mercapto-1,3-oxazole

3-((2-OXAZOLYLTHIO)METHYL)-7-(2-(1H-TETRAZOL-1-YL)ACETAMIDO)-3CEPHEM-4-CARBOXYLIC ACID

Conditions

Conditions	Yield
In dimethylsulfoxide-d6; nitromethane; water	85.7%

...Expand

10493-44-4

1,1,2-trifluoro-4-bromobut-1-ene

32091-51-3

2-mercapto-1,3-oxazole

359631-01-9

2-(3,4,4-trifluoro-3-butenylthio)oxazole

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile	82.7%

542-69-8

1-iodo-butane

32091-51-3

2-mercapto-1,3-oxazole

620632-04-4

2-(n-butylthio)oxazole

Conditions

Conditions	Yield
Stage #1: 2-mercapto-1,3-oxazole With potassium hydride In tetrahydrofuran at -60℃; for 0.5h; Stage #2: 1-iodo-butane In tetrahydrofuran at 20℃; for 2h; Further stages.;	79%
Stage #1: 2-mercapto-1,3-oxazole With potassium hydride In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere; Stage #2: 1-iodo-butane In tetrahydrofuran at -78 - 20℃; for 3.5h; Inert atmosphere;	74%

32091-51-3

2-mercapto-1,3-oxazole

74-88-4

methyl iodide

201017-90-5

2-(methylthio)oxazole

Conditions

Conditions	Yield
Stage #1: 2-mercapto-1,3-oxazole With potassium hydride In tetrahydrofuran at -60℃; for 0.5h; Inert atmosphere; Stage #2: methyl iodide In tetrahydrofuran at -60℃; for 3.5h; Inert atmosphere;	69%

865-50-9

iodomethane-d3

32091-51-3

2-mercapto-1,3-oxazole

1268685-67-1

2-(trideuterothiomethyl)oxazole

Conditions

Conditions	Yield
Stage #1: 2-mercapto-1,3-oxazole With potassium hydride In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere; Stage #2: iodomethane-d3 In tetrahydrofuran at -78 - 20℃; for 3.5h; Inert atmosphere;	51%

3-(acetoxymethyl)-7-[2-[(2,5-dichlorophenyl)thio]acetamido]-3-cephem-4-carboxylic acid

32091-51-3

2-mercapto-1,3-oxazole

7-[2-[(2,5-dichlorophenyl)thio]acetamido]-3-[(2-oxazolyl)thiomethyl]-3-cephem-4-carboxylic acid

Conditions

Conditions	Yield
With sodium hydrogencarbonate

5460-29-7

2-(3-bromopropyl)isoindole-1,3-dione

32091-51-3

2-mercapto-1,3-oxazole

A

288-42-6

oxazol

B

38585-54-5

N-(3-oxazol-2-ylsulfanyl-propyl)-phthalimide

Conditions

Conditions	Yield
With sodium ethanolate; sodium In ethanol
With sodium ethanolate; sodium In ethanol
With sodium ethanolate; sodium In ethanol

...Expand

2(3H)-Oxazolethione Specification