• Name

  2-Acetyl-2-thiazoline

• EINECS
• CAS No. 29926-41-8
• Article Data4
• CAS DataBase
• Density 1.29 g/cm³
• Solubility
• Melting Point 26-30 °C(lit.)
• Formula C₅H₇NOS
• Boiling Point 223.8 °C at 760 mmHg
• Molecular Weight 129.183
• Flash Point 89.2 °C
• Transport Information UN 2811 6.1/PG 3
• Appearance Light yellow liquid
• Safety 26
• Risk Codes 22-36
• Molecular Structure
• Hazard Symbols Xn
• Synonyms Ethanone, 1-(4,5-dihydro-2-thiazolyl)-;1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone;
• PSA 54.73000
• LogP 0.15630

Synthetic route

67399-73-9

2-acetyl-1,3-thiazolidine

29926-41-8

1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; ruthenium trichloride; N,N,N,N,-tetramethylethylenediamine In acetonitrile at 20℃; for 4h; Catalytic oxidation;	70%

16982-46-0

2-ethyl-2-thiazoline

29926-41-8

1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone

Conditions

Conditions	Yield
Stage #1: 2-ethyl-2-thiazoline With tert.-butylhydroperoxide; selenium(IV) oxide In dichloromethane at 20℃; for 3h; Stage #2: With triphenylphosphine In dichloromethane at 0℃; for 12h;	40%

2-(1-hydroxyethyl)-4,5-dihydrothiazole

29926-41-8

1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone

Conditions

Conditions	Yield
In water at 100℃; for 0.166667h; Thermodynamic data; Product distribution; E(a); var. temp., time and pH;

156-57-0

2-mercaptoethylamine hydrochloride

78-98-8

2-oxopropanal

29926-41-8

1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone

Conditions

Conditions	Yield
With potassium phosphate buffer; sodium at 6℃; for 18h; Mechanism;

29926-41-8

1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone

[1-(4,5-Dihydro-thiazol-2-yl)-eth-(E)-ylidene]-hydrazine

Conditions

Conditions	Yield
With hydrazine hydrate In ethanol Condensation; Heating;	72%

29926-41-8

1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone

4637-24-5

N,N-dimethyl-formamide dimethyl acetal

1233858-23-5

(E)-1-(4,5-dihydrothiazol-2-yl)-3-(dimethylamino)prop-2-en-1-one

Conditions

Conditions	Yield
at 160℃; for 0.333333h; Microwave irradiation;	64%

29926-41-8

1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone

79-19-6

thiosemicarbazide

2-acetyl-2-thiazoline thiosemicarbazone

Conditions

Conditions	Yield
With acetic acid In acetonitrile for 2h; Reflux;	52%

29926-41-8

1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone

762-42-5

dimethyl acetylenedicarboxylate

1233858-39-3

dimethyl 6-methyl-5-oxo-2,3,5,7a-tetrahydropyrrolo[2,1-b]thiazole-7,7a-dicarboxylate

Conditions

Conditions	Yield
In acetonitrile at 60℃; for 0.25h; Microwave irradiation;	19%

29926-41-8

1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone

3-methyl-5,6-dihydro-thiazolo[3,2-c][1,2,3]triazole

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 72 percent / hydrazine hydrate / ethanol / Heating 2: 88 percent / PhI(OAc)2 / CH2Cl2 / 0.5 h / 20 °C View Scheme

29926-41-8

1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone

192643-90-6

ethyl 2-(4-hydrazinophenyl)-2-methylpropanoate

1076220-44-4

ethyl 2-methyl-2-(2-(1,3-thiazol-2-yl)-1H-indol-5-yl)propanoate

Conditions

Conditions	Yield
With acetic acid; zinc(II) chloride In ethanol

2-Acetyl-2-thiazoline Chemical Properties

2-Acetyl-2-thiazoline Safety Profile

2-Acetyl-2-thiazoline Specification