2-Amino-5-fluorobenzoic acid

The 2-Amino-5-Fluorobenzoic acid is an organic compound with the formula C₇H₆FNO₂. The IUPAC name of this chemical is 2-amino-5-fluorobenzoic acid. With the CAS registry number 446-08-2, it is also named as Benzoic acid, 2-amino-5-fluoro-. The product's categories are Fluorin-contained Benzoic Acid Series; Fine Chemical & Intermediates; Fluorobenzene; Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts; Carboxylic Acids; Phenyls & Phenyl-Het; Benzoic acid; Nucleotides and Nucleosides; Aromatics Compounds; Benzoic Acid Series; Aromatics; 5-FOA; Bases & Related Reagents; Nucleotides; Carboxylic Acids; Phenyls & Phenyl-Het. Besides, it is a white to light yellow crystal powder, which should be stored in a closed cool and dry place.

Physical properties about 2-Amino-5-Fluorobenzoic acid are: (1)ACD/LogP: 1.64; (2)ACD/LogD (pH 5.5): 0.33; (3)ACD/LogD (pH 7.4): -1.23; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 9.12; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 3; (9)#H bond donors: 3; (10)#Freely Rotating Bonds: 2; (11)Polar Surface Area: 29.54 Å²; (12)Index of Refraction: 1.606; (13)Molar Refractivity: 37.41 cm³; (14)Molar Volume: 108.4 cm³; (15)Polarizability: 14.83×10^-24cm³; (16)Surface Tension: 60.4 dyne/cm; (17)Density: 1.43 g/cm³; (18)Flash Point: 146.2 °C; (19)Enthalpy of Vaporization: 59.08 kJ/mol; (20)Boiling Point: 318.2 °C at 760 mmHg; (21)Vapour Pressure: 0.000154 mmHg at 25°C.

Uses of 2-Amino-5-Fluorobenzoic acid: it can be used to produce 5-fluoro-N-isopropylanthranilic acid by heating. It will need reagent pyridine with reaction time of 4 hours. The yield is about 54.36%.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. When you are using it, wear suitable gloves and eye/face protection. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(O)c1cc(F)ccc1N
(2)InChI: InChI=1/C7H6FNO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,9H2,(H,10,11)
(3)InChIKey: FPQMGQZTBWIHDN-UHFFFAOYAL
(4)Std. InChI: InChI=1S/C7H6FNO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,9H2,(H,10,11)
(5)Std. InChIKey: FPQMGQZTBWIHDN-UHFFFAOYSA-N