Product Name

  • Name

    B-DIMETHYLAMINOETHYL BROMIDE HYDROBROMIDE

  • EINECS 220-680-4
  • CAS No. 2862-39-7
  • Density
  • Solubility
  • Melting Point 188.5-188.9 °C(Solv: ethyl acetate (141-78-6); ethanol, 95% (64-17-5)(8:5))
  • Formula C4H11Br2N
  • Boiling Point 121.7 °C at 760 mmHg
  • Molecular Weight 232.946
  • Flash Point 27.4 °C
  • Transport Information
  • Appearance
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 2862-39-7 (B-DIMETHYLAMINOETHYL BROMIDE HYDROBROMIDE)
  • Hazard Symbols
  • Synonyms Ethanamine,2-bromo-N,N-dimethyl-, hydrobromide (9CI);Ethylamine, 2-bromo-N,N-dimethyl-,hydrobromide (6CI,7CI,8CI);(2-Bromoethyl)dimethylamine hydrobromide;2-(Dimethylamino)ethyl bromide hydrobromide;2-(N,N-Dimethylamino)ethyl bromidehydrobromide;2-Dimethylamino-1-bromoethane hydrobromide;N,N-Dimethyl-beta-bromoethylamine hydrobromide;Ethanamine,2-bromo-N,N-dimethyl-, hydrobromide (1:1);
  • PSA 3.24000
  • LogP 1.90100

Synthetic route

2-(N,N-dimethylamino)ethanol
108-01-0

2-(N,N-dimethylamino)ethanol

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

Conditions
ConditionsYield
With hydrogen bromide at 0℃; und folgendes Kochen;
2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

(3R,4S)-3-Hydroxy-4-(4-methoxy-phenyl)-7-trifluoromethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one
138335-08-7

(3R,4S)-3-Hydroxy-4-(4-methoxy-phenyl)-7-trifluoromethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one

cis-3-hydroxy-1-<2-(dimethylamino)ethyl>-1,3,4,5-tetrahydro-4-(4-methoxyphenyl)-7-(trifluoromethyl)-2H-1-benzazepin-2-one
138337-25-4, 138383-41-2

cis-3-hydroxy-1-<2-(dimethylamino)ethyl>-1,3,4,5-tetrahydro-4-(4-methoxyphenyl)-7-(trifluoromethyl)-2H-1-benzazepin-2-one

Conditions
ConditionsYield
With barium dihydroxide; benzyltrimethylammonium chloride In dichloromethane; water for 16h;93%
2-ethyl-4-methyl-N-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)oxazole-5-carboxamide

2-ethyl-4-methyl-N-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)oxazole-5-carboxamide

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

N-(4-(1-(2-(dimethylamino)ethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)-2-ethyl-4-methyloxazole-5-carboxamide

N-(4-(1-(2-(dimethylamino)ethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)-2-ethyl-4-methyloxazole-5-carboxamide

Conditions
ConditionsYield
Stage #1: 2-ethyl-4-methyl-N-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)oxazole-5-carboxamide With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 2-(dimethylamino)ethyl bromide hydrobromide In N,N-dimethyl-formamide; mineral oil at 20℃; for 21.5h;		90%
ethyl 1H-imidazole-2-carboxylate
33543-78-1

ethyl 1H-imidazole-2-carboxylate

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

1-(2-(dimethylamino)ethyl)-1H-imidazole-2-carboxylic acid ethyl ester

1-(2-(dimethylamino)ethyl)-1H-imidazole-2-carboxylic acid ethyl ester

Conditions
ConditionsYield
Stage #1: ethyl 1H-imidazole-2-carboxylate With potassium carbonate In acetonitrile for 0.5h;
Stage #2: 2-(dimethylamino)ethyl bromide hydrobromide In acetonitrile at 80℃; for 3h;		87.7%
Stage #1: ethyl 1H-imidazole-2-carboxylate With potassium carbonate In acetonitrile for 0.5h;
Stage #2: 2-(dimethylamino)ethyl bromide hydrobromide In acetonitrile at 80℃; for 3h;		87.7%
2,4-dimethyl-N-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)oxazole-5-carboxamide

2,4-dimethyl-N-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)oxazole-5-carboxamide

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

N-(4-(1-(2-(dimethylamino)ethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)-2,4-dimethyloxazole-5-carboxamide

N-(4-(1-(2-(dimethylamino)ethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)-2,4-dimethyloxazole-5-carboxamide

Conditions
ConditionsYield
Stage #1: 2,4-dimethyl-N-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)oxazole-5-carboxamide With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 2-(dimethylamino)ethyl bromide hydrobromide In N,N-dimethyl-formamide; mineral oil at 20℃; for 21.5h;		86%
2-isopropyl-4-methyl-N-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)oxazole-5-carboxamide

2-isopropyl-4-methyl-N-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)oxazole-5-carboxamide

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

N-(4-(1-(2-(dimethylamino)ethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)-2-isopropyl-4-methyloxazole-5-carboxamide

N-(4-(1-(2-(dimethylamino)ethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)-2-isopropyl-4-methyloxazole-5-carboxamide

Conditions
ConditionsYield
Stage #1: 2-isopropyl-4-methyl-N-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)oxazole-5-carboxamide With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 2-(dimethylamino)ethyl bromide hydrobromide In N,N-dimethyl-formamide; mineral oil at 20℃; for 21.5h;		83%
(S)-4-(3,4-dimethoxybenzyl)-3-(3-hydroxybenzyl)oxazolidin-2-one

(S)-4-(3,4-dimethoxybenzyl)-3-(3-hydroxybenzyl)oxazolidin-2-one

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

(S)-4-(3,4-dimethoxybenzyl)-3-(3-(2-(dimethylamino)ethoxy)benzyl)oxazolidin-2-one

(S)-4-(3,4-dimethoxybenzyl)-3-(3-(2-(dimethylamino)ethoxy)benzyl)oxazolidin-2-one

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 50℃;79%
2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

phenol
108-95-2

phenol

dimethyl(2-phenoxyethyl)amine
13468-02-5

dimethyl(2-phenoxyethyl)amine

Conditions
ConditionsYield
With sodium hydride In diethyl ether; N,N-dimethyl-formamide for 15h; Ambient temperature;78%
2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

C19H17ClN2O2

C19H17ClN2O2

C23H26ClN3O2

C23H26ClN3O2

Conditions
ConditionsYield
Stage #1: C19H17ClN2O2 With sodium hydride In N,N-dimethyl-formamide; mineral oil at 40℃; for 0.5h;
Stage #2: 2-(dimethylamino)ethyl bromide hydrobromide In N,N-dimethyl-formamide; mineral oil at 40℃;		78%
3-allyl-2-thioxo-2,3-dihydro-1H-spiro[benzo[h]quinazoline-5,1'-cyclohexan]-4(6H)-one
328002-54-6

3-allyl-2-thioxo-2,3-dihydro-1H-spiro[benzo[h]quinazoline-5,1'-cyclohexan]-4(6H)-one

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

C24H31N3OS
1239648-04-4

C24H31N3OS

Conditions
ConditionsYield
With potassium hydroxide In butanone at 70℃; for 16h; Inert atmosphere;75%
(S)-1-(3-hydroxybenzyl)-5-(3,4-dimethoxybenzyl)pyrrolidin-2-one

(S)-1-(3-hydroxybenzyl)-5-(3,4-dimethoxybenzyl)pyrrolidin-2-one

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

(S)-1-(3-(2-(dimethylamino)ethoxy)benzyl)-5-(3,4-dimethoxybenzyl)pyrrolidin-2-one

(S)-1-(3-(2-(dimethylamino)ethoxy)benzyl)-5-(3,4-dimethoxybenzyl)pyrrolidin-2-one

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 50℃;70%
3-ethyl-5-methyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carbaldehyde

3-ethyl-5-methyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carbaldehyde

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

1-[2-(dimethylamino)ethyl]-3-ethyl-5-methyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carbaldehyde

1-[2-(dimethylamino)ethyl]-3-ethyl-5-methyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carbaldehyde

Conditions
ConditionsYield
Stage #1: 3-ethyl-5-methyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carbaldehyde With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 0.166667h;
Stage #2: 2-(dimethylamino)ethyl bromide hydrobromide In N,N-dimethyl-formamide at 100℃; for 2h; Microwave irradiation;		69%
(S)-1-(3-methoxy-4-hydroxybenzyl)-5-(3,4-dimethoxybenzyl)pyrrolidin-2-one

(S)-1-(3-methoxy-4-hydroxybenzyl)-5-(3,4-dimethoxybenzyl)pyrrolidin-2-one

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

(S)-1-(3-methoxy-4-(2-(dimethylamino)ethoxy)benzyl)-5-(3,4-dimethoxybenzyl)pyrrolidin-2-one

(S)-1-(3-methoxy-4-(2-(dimethylamino)ethoxy)benzyl)-5-(3,4-dimethoxybenzyl)pyrrolidin-2-one

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 50℃;68%
2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

methyl 5-bromo-6-oxo-1,6-dihydropyridine-3-carboxylate
381247-99-0

methyl 5-bromo-6-oxo-1,6-dihydropyridine-3-carboxylate

methyl 5-bromo-1-(2-(dimethylamino)ethyl)-6-oxo-1,6-dihydropyridine-3-carboxylate

methyl 5-bromo-1-(2-(dimethylamino)ethyl)-6-oxo-1,6-dihydropyridine-3-carboxylate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 10h;67%
2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

Benzo[b]thiophene
95-15-8

Benzo[b]thiophene

(2-benzo[b]thiophen-2-yl-ethyl)-dimethyl-amine
10275-27-1

(2-benzo[b]thiophen-2-yl-ethyl)-dimethyl-amine

Conditions
ConditionsYield
Stage #1: Benzo[b]thiophene With n-butyllithium In tetrahydrofuran; hexanes
Stage #2: 2-(dimethylamino)ethyl bromide hydrobromide In tetrahydrofuran; hexanes at -78 - 0℃; for 5h; Product distribution / selectivity;		65%
Stage #1: Benzo[b]thiophene With n-butyllithium In tetrahydrofuran; hexane at -78℃;
Stage #2: 2-(dimethylamino)ethyl bromide hydrobromide In tetrahydrofuran; hexane at -78 - 0℃;		65%
1-benzofurane
271-89-6

1-benzofurane

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

(2-benzofuran-2-yl-ethyl)-dimethyl-amine
1186219-57-7

(2-benzofuran-2-yl-ethyl)-dimethyl-amine

Conditions
ConditionsYield
Stage #1: 1-benzofurane With n-butyllithium In tetrahydrofuran; hexane at -78℃;
Stage #2: 2-(dimethylamino)ethyl bromide hydrobromide In tetrahydrofuran; hexane at -78 - 20℃;		62%
2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

3-chloro-8-methoxy-11H-indolo<3,2-c>quinoline
116792-06-4

3-chloro-8-methoxy-11H-indolo<3,2-c>quinoline

[2-(3-chloro-8-methoxy-indolo[3,2-c]quinolin-11-yl)-ethyl]-dimethyl-amine
65287-63-0

[2-(3-chloro-8-methoxy-indolo[3,2-c]quinolin-11-yl)-ethyl]-dimethyl-amine

Conditions
ConditionsYield
With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride In toluene at 70℃; for 5h;61%
methyl 4-[(6-cyclopentyl-2-methyl-3-oxo-2,6,8,10-tetrazabicyclo[5.4.0]undeca-7,9,11-trien-9-yl)amino]-3-hydroxy-benzoate

methyl 4-[(6-cyclopentyl-2-methyl-3-oxo-2,6,8,10-tetrazabicyclo[5.4.0]undeca-7,9,11-trien-9-yl)amino]-3-hydroxy-benzoate

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

methyl 4-[(2-cyclopentyl-6-methyl-5-oxo-2,6,9,11-tetrazabicyclo[5.4.0]undeca-8,10,12-trien-10-yl)amino]-3-(2-dimethylaminoethoxy)benzoate

methyl 4-[(2-cyclopentyl-6-methyl-5-oxo-2,6,9,11-tetrazabicyclo[5.4.0]undeca-8,10,12-trien-10-yl)amino]-3-(2-dimethylaminoethoxy)benzoate

Conditions
ConditionsYield
With potassium carbonate In ISOPROPYLAMIDE at 100℃; for 1h;57%
2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

tert-butyl 1,2,5-thiadiazolidine-2-carboxylate1,1-dioxide
263719-76-2

tert-butyl 1,2,5-thiadiazolidine-2-carboxylate1,1-dioxide

C11H23N3O4S

C11H23N3O4S

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 20℃;55%
2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

tert-butyl[4-(2-dimethyl-aminoethyl)-5-oxoperhydro-1,4-thiazepin-6-yl]carbamate
889214-68-0

tert-butyl[4-(2-dimethyl-aminoethyl)-5-oxoperhydro-1,4-thiazepin-6-yl]carbamate

Conditions
ConditionsYield
Stage #1: (hexahydro-5-oxo-1,4-thiazepin-6-yl)carbamic acid-(1,1-dimethylethyl)ester With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 1h;
Stage #2: 2-(dimethylamino)ethyl bromide hydrobromide With sodium iodide In N,N-dimethyl-formamide for 1.5h;		52%
N'-((5-cyanopyrazolo[1,5-a]pyridin-3-yl)methylene)-2-methyl-5-nitrobenzenesulfonohydrazide
1101118-71-1

N'-((5-cyanopyrazolo[1,5-a]pyridin-3-yl)methylene)-2-methyl-5-nitrobenzenesulfonohydrazide

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

N'-((5-cyanopyrazolo[1,5-a]pyridin-3-yl)methylene)-N-(2-(dimethylamino)ethyl)-2-methyl-5-nitrobenzenesulfonohydrazide
1101118-79-9

N'-((5-cyanopyrazolo[1,5-a]pyridin-3-yl)methylene)-N-(2-(dimethylamino)ethyl)-2-methyl-5-nitrobenzenesulfonohydrazide

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 2h;47%
2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

N,N-dimethyl-5-amino-2H-pyrido[3',2':5,6]thiopyrano[4,3,2-cd]indazole-2-ethanamine
187658-63-5

N,N-dimethyl-5-amino-2H-pyrido[3',2':5,6]thiopyrano[4,3,2-cd]indazole-2-ethanamine

N'-[2-[2-(dimethylamino)ethyl]-2H-pyrido[3',2':5,6]thiopyrano[4,3,2-cd]indazol-5-yl]-N,N-dimethyl-1,2-ethanediamine

N'-[2-[2-(dimethylamino)ethyl]-2H-pyrido[3',2':5,6]thiopyrano[4,3,2-cd]indazol-5-yl]-N,N-dimethyl-1,2-ethanediamine

Conditions
ConditionsYield
With potassium carbonate In toluene for 15h; Heating;45%
3,3-bis(4-hydroxyphenyl)-2-(thiophen-2-yl)acrylonitrile

3,3-bis(4-hydroxyphenyl)-2-(thiophen-2-yl)acrylonitrile

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

3,3-bis(4-(2-(dimethylamino)ethoxy)phenyl)-2-(thiophen-2-yl)acrylonitrile

3,3-bis(4-(2-(dimethylamino)ethoxy)phenyl)-2-(thiophen-2-yl)acrylonitrile

Conditions
ConditionsYield
With caesium carbonate In acetonitrile for 18h; Reflux;42%
2-(4-fluorophenyl)oxazolo[4,5-c]quinolin-4(5H)-one
148563-23-9

2-(4-fluorophenyl)oxazolo[4,5-c]quinolin-4(5H)-one

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

5-(2-(dimethylamino)ethyl)-2-(4-fluorophenyl)oxazolo[4,5-c]quinolin-4(5H)-one

5-(2-(dimethylamino)ethyl)-2-(4-fluorophenyl)oxazolo[4,5-c]quinolin-4(5H)-one

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 130℃; for 3h;39%
2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

N,N-diethyl-5-amino-2H-pyrido[3',2':5,6]thiopyrano[4,3,2-cd]indazole-2-ethanamine
187658-45-3

N,N-diethyl-5-amino-2H-pyrido[3',2':5,6]thiopyrano[4,3,2-cd]indazole-2-ethanamine

N'-[2-[2-(diethylamino)ethyl]-2H-pyrido[3',2':5,6]thiopyrano[4,3,2-cd]indazol-5-yl]-N,N-dimethyl-1,2-ethanediamine

N'-[2-[2-(diethylamino)ethyl]-2H-pyrido[3',2':5,6]thiopyrano[4,3,2-cd]indazol-5-yl]-N,N-dimethyl-1,2-ethanediamine

Conditions
ConditionsYield
With potassium carbonate In toluene for 15h; Heating;25%
5-(2-hydroxyphenyl)-9-[(2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl]-3,9-diazaspiro[5.5]undecan-2-one

5-(2-hydroxyphenyl)-9-[(2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl]-3,9-diazaspiro[5.5]undecan-2-one

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

5-{2-[2-(dimethylamino)ethoxy]phenyl}-9-[(2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl]-3,9-diazaspiro[5.5]undecan-2-one

5-{2-[2-(dimethylamino)ethoxy]phenyl}-9-[(2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl]-3,9-diazaspiro[5.5]undecan-2-one

Conditions
ConditionsYield
Stage #1: 5-(2-hydroxyphenyl)-9-[(2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl]-3,9-diazaspiro[5.5]undecan-2-one With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 0.166667h;
Stage #2: 2-(dimethylamino)ethyl bromide hydrobromide In N,N-dimethyl-formamide at 80℃; for 12h;		25%
tert-butyl 4-oxo-3-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxylate

tert-butyl 4-oxo-3-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxylate

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

tert-butyl 3-[2-[2-(dimethylamino)ethyl-(2,2,2-trifluoroethyl)amino]-2-oxo-ethyl]-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxylate

tert-butyl 3-[2-[2-(dimethylamino)ethyl-(2,2,2-trifluoroethyl)amino]-2-oxo-ethyl]-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxylate

Conditions
ConditionsYield
With caesium carbonate In acetonitrile at 90℃; for 16h; Sealed tube;20.8%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

N,N-dimethyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethan-1-amine
877149-80-9

N,N-dimethyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethan-1-amine

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 70℃;20%
N-(1-(5-(3-cyano-6-hydroxypyrazolo[1,5-a]pyridin-4-yl)pyridin-2-yl)-4-methylpiperidin-4-yl)-5-fluoro-2-methylbenzamide

N-(1-(5-(3-cyano-6-hydroxypyrazolo[1,5-a]pyridin-4-yl)pyridin-2-yl)-4-methylpiperidin-4-yl)-5-fluoro-2-methylbenzamide

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

N-(1-(5-(3-cyano-6-(2-(dimethylamino)ethoxy)pyrazolo[1,5-a]pyridin-4-yl)pyridin-2-yl)-4-methylpiperidin-4-yl)-5-fluoro-2-methylbenzamide

N-(1-(5-(3-cyano-6-(2-(dimethylamino)ethoxy)pyrazolo[1,5-a]pyridin-4-yl)pyridin-2-yl)-4-methylpiperidin-4-yl)-5-fluoro-2-methylbenzamide

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl acetamide at 60℃;18%
C30H36N2O3

C30H36N2O3

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

C34H45N3O3

C34H45N3O3

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In ethanol for 9h; Reflux;16.5%
[4-[5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]pyrrol-2-yl]phenyl]methanol

[4-[5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]pyrrol-2-yl]phenyl]methanol

2-(dimethylamino)ethyl bromide hydrobromide
2862-39-7

2-(dimethylamino)ethyl bromide hydrobromide

2-[[4-[5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]pyrrol-2-yl]phenyl]methoxy]-N,N-dimethylethanamine hydrochloride

2-[[4-[5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]pyrrol-2-yl]phenyl]methoxy]-N,N-dimethylethanamine hydrochloride

Conditions
ConditionsYield
Stage #1: [4-[5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]pyrrol-2-yl]phenyl]methanol With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.5h; Inert atmosphere;
Stage #2: 2-(dimethylamino)ethyl bromide hydrobromide In N,N-dimethyl-formamide at 90℃; for 18h; Inert atmosphere;
Stage #3: With hydrogenchloride In tetrahydrofuran; 1,4-dioxane at 20℃; for 0.5h;		16%

2-Bromo-N,N-dimethylethylamine hydrobromide Specification

The 2-Bromo-N,N-dimethylethanaminium bromide, with the CAS registry number 2862-39-7, is also known as N,N-Dimethyl-beta-bromoethylamine hydrobromide. Its EINECS number is 220-680-4. This chemical's molecular formula is C4H11Br2N and formula weight is 232.94. What's more, its IUPAC name is 2-bromoethyl(dimethyl)azanium bromide. Its classification code is Drug/Therapeutic Agent.

Physical properties of 2-Bromo-N,N-dimethylethanaminium bromide are: (1)ACD/LogP: 1.04; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -1.49; (4)ACD/LogD (pH 7.4): 0.21; (5)ACD/BCF (pH 5.5): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 12.89; (8)#H bond acceptors: 1; (9)#H bond donors: 0; (10)#Freely Rotating Bonds: 2; (11)Flash Point: 27.4 °C; (12)Enthalpy of Vaporization: 35.98 kJ/mol; (13)Boiling Point: 121.7 °C at 760 mmHg; (14)Vapour Pressure: 14.4 mmHg at 25°C.

Uses of 2-Bromo-N,N-dimethylethanaminium bromide: it can be used to produce dimethyl-(2-phenoxy-ethyl)-amine at the ambient temperature. It will need reagent NaH and solvent dimethylformamide, diethyl ether with the reaction time of 15 hours. The yield is about 78%.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C[NH+](C)CCBr.[Br-]
(2)InChI: InChI=1S/C4H10BrN.BrH/c1-6(2)4-3-5;/h3-4H2,1-2H3;1H
(3)InChIKey: MFRUVSDIZTZFFL-UHFFFAOYSA-N

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