2-Bromobenzyl bromide

The IUPAC name of 2-Bromobenzyl bromide is 1-bromo-2-(bromomethyl)benzene. With the CAS registry number 3433-80-5, it is also named as alpha-2-Dibromotoluene. The product's categories are Aromatic Halides (substituted); Benzyl. It is white to off-white powder which is miscible with alcohol, ether, acetic acid and carbon disulfide. This chemical must be sealed in the container and avoided direct sunshine.  

The other characteristics of this product can be summarized as: (1)ACD/LogP: 3.69; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 3.69; (4)ACD/LogD (pH 7.4): 3.69; (5)ACD/BCF (pH 5.5): 375.8; (6)ACD/BCF (pH 7.4): 375.8; (7)ACD/KOC (pH 5.5): 2425.28; (8)ACD/KOC (pH 7.4): 2425.28; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 1; (12)Index of Refraction: 1.605; (13)Molar Refractivity: 46.59 cm³; (14)Molar Volume: 135.1 cm³; (15)Polarizability: 18.47×10^-24 cm³; (16)Surface Tension: 43.3 dyne/cm; (17)Enthalpy of Vaporization: 47.06 kJ/mol; (18)Vapour Pressure: 0.0298 mmHg at 25°C; (19)Rotatable Bond Count: 1; (20)Exact Mass: 249.881579; (21)MonoIsotopic Mass: 247.883625; (22)Heavy Atom Count: 9; (23)Complexity: 83.

Preparation of 2-Bromobenzyl bromide: It can be obtained by bromination of o-bromotoluene. Using fluorescent lamp to irradiate o-bromotoluene which is in reactor, slowly dropping bromine at the 160-180 °C, and tail gas is absorpted by water. When finished, it continues to react 0.5h. Decompressing and cooling to below 40 °C, then we can get the product.

Uses of 2-Bromobenzyl bromide: It can be used as pharmaceutical intermediate in organic synthesis. And it reacts with dimethylamine to get (2-bromo-benzyl)-dimethyl-amine. This reaction needs reagent solvent benzene at ambient temperature. The reaction time is 50 hours. The yield is 70%.

When you are using this chemical, please be cautious about it as the following:
It is toxic by inhalation and irritating to respiratory system, so people should not breathe dust. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

People can use the following data to convert to the molecule structure. 
1. SMILES:BrCc1ccccc1Br
2. InChI:InChI=1/C7H6Br2/c8-5-6-3-1-2-4-7(6)9/h1-4H,5H2 
3. InChIKey:LZSYGJNFCREHMD-UHFFFAOYAT