2-Chloro-4-fluorophenol

The Phenol,2-chloro-4-fluoro-, with its CAS registry number 1996-41-4, has the IUPAC name of 2-chloro-4-fluorophenol. For being a kind of light yellow liquid, it is usually applied as the intermediate of pharmaceutic, pesticide and liquid crystal materials, with its product categories including Fluorobenzene; Phenol&Thiophenol&Mercaptan; API intermediates; Chlorine Compounds; Fluorine Compounds; Phenols; Organic Building Blocks; Oxygen Compounds. slightly soluble

The characteristics of this chemical are as below: (1)ACD/LogP: 1.89; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.88; (4)ACD/LogD (pH 7.4): 1.85; (5)ACD/BCF (pH 5.5): 15.93; (6)ACD/BCF (pH 7.4): 14.78; (7)ACD/KOC (pH 5.5): 252.4; (8)ACD/KOC (pH 7.4): 234.21; (9)#H bond acceptors: 1; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 9.23; (13)Index of Refraction: 1.547; (14)Molar Refractivity: 33.02 cm³; (15)Molar Volume: 104 cm³; (16)Polarizability: 13.09×10^-24 cm³; (17)Surface Tension: 42.2 dyne/cm; (18)Density: 1.408 g/cm³; (19)Flash Point: 75 °C; (20)Enthalpy of Vaporization: 48.3 kJ/mol; (21)Boiling Point: 227.6 °C at 760 mmHg; (22)Vapour Pressure: 0.0511 mmHg at 25°C; (23)Exact Mass: 145.993471; (24)MonoIsotopic Mass: 145.993471; (25)Topological Polar Surface Area: 20.2; (26)Heavy Atom Count: 9; (27)Complexity: 99.1; (28)Covalently-Bonded Unit Count: 1.

Use of this chemical: Phenol,2-chloro-4-fluoro- could react with 3'-chloro-4"-nitroacetophenone to produce 1-[3-(2-chloro-4-fluoro-phenoxy)-4-nitro-phenyl]-ethanone. This reaction could happen in the presence of the reagent of potassium carbonate and the solvent of xylene, and it needs the reaction time of 5.5 hours in the condition of heating.

When you are dealing with this chemical, you should be more cautious. For one thing, it is irritating to eyes, respiratory system and skin and may cause inflammation to the skin or other mucous membranes. If by inhalation, in contact with skin and if swallowed, it will be dangerous. For another thing, it is harmful which may cause damage to health. Therefore, you shoudl wear suitable protective clothing, gloves and eye/face protection, and if in case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

In adddition, you could convert the following datas into the molecular structure:
(1)Canonical SMILES: C1=CC(=C(C=C1F)Cl)O
(2)InChI: InChI=1S/C6H4ClFO/c7-5-3-4(8)1-2-6(5)9/h1-3,9H
(3)InChIKey: IGYXYGDEYHNFFT-UHFFFAOYSA-N