Product Name

  • Name

    2-Hydroxy Imipramine

  • EINECS
  • CAS No. 303-70-8
  • Article Data2
  • CAS DataBase
  • Density 1.107g/cm3
  • Solubility
  • Melting Point 130-132°C
  • Formula C19H24 N2 O
  • Boiling Point 469°Cat760mmHg
  • Molecular Weight 296.412
  • Flash Point 239.5°C
  • Transport Information
  • Appearance
  • Safety Poison by intravenous route. Moderately toxic by ingestion. Experimental teratogenic effects. When heated to decomposition it emits toxic fumes of NOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 303-70-8 (2-Hydroxy Imipramine)
  • Hazard Symbols
  • Synonyms 2-Hydroxyimipramine;G 33679
  • PSA 26.71000
  • LogP 3.64560

2-Hydroxyimipramine Chemical Properties

Molecular structure of 2-Hydroxyimipramine (CAS NO.303-70-8) is:

Product Name: 2-Hydroxyimipramine
CAS Registry Number: 303-70-8
IUPAC Name: 11-[3-(dimethylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepin-8-ol
Molecular Weight: 296.40666 [g/mol]
Molecular Formula: C19H24N2O
XLogP3: 4.4
H-Bond Donor: 1
H-Bond Acceptor: 3 
Melting Point: 130-132°C
Surface Tension: 44.8 dyne/cm
Density: 1.107 g/cm3
Flash Point: 239.5 °C
Enthalpy of Vaporization: 75.92 kJ/mol
Boiling Point: 469 °C at 760 mmHg
Vapour Pressure: 2.03E-09 mmHg at 25°C
Product Categories: Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals 
Classification Code: Drug / Therapeutic Agent ;Reproductive Effect 

2-Hydroxyimipramine Uses

 2-Hydroxyimipramine (CAS NO.303-70-8) can be used as a metabolite of Imipramine.

2-Hydroxyimipramine Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 29mg/kg (29mg/kg)   Medicina et Pharmacologia Experimentalis. Vol. 15, Pg. 187, 1966.
mouse LD50 oral 733mg/kg (733mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1617, 1969.
rabbit LD50 intravenous 12500ug/kg (12.5mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1617, 1969.
rat LD50 intravenous 19mg/kg (19mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1617, 1969.
rat LD50 oral 2980mg/kg (2980mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1617, 1969.

2-Hydroxyimipramine Safety Profile

Poison by intravenous route. Moderately toxic by ingestion. Experimental teratogenic effects. When heated to decomposition it emits toxic fumes of NOx.

2-Hydroxyimipramine Specification

 2-Hydroxyimipramine , its cas register number is 303-70-8. It also can be called 2-OH-IP ; 5-(3-(Dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepin-2-ol ; 5-(3-(Dimethylamino)propyl)-2-hydroxy-10,11-dihydro-5H-dibenz(b,f)azepine ; 5-21-04-00033 (Beilstein Handbook Reference) ; BRN 1547775 ; G 33679 ; GP 33679 ; Hydroxyimipramine ; 5H-Dibenz(b,f)azepin-2-ol, 10,11-dihydro-5-(3-(dimethylamino)propyl)- . It is a tan solid.

Related Products

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View