25I-NBOH HCL supplier | CasNO.919797-20-9

Name
25I-NBOH HCL
EINECS
CAS No. 919797-20-9
Article Data4
CAS DataBase
Density 1.493±0.06 g/cm3(Predicted)
Solubility
Melting Point
Formula C17H20INO3
Boiling Point 497.0±45.0 °C(Predicted)
Molecular Weight 413.255
Flash Point
Transport Information
Appearance
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms NBOH-2CI;25I-NBOH;25I-NBOH HCL;Cimbi-27;
PSA 50.72000
LogP 3.73720

25I-NBOH HCL Specification

25I-NBOH (NBOH-2CI, Cimbi-27, 2-C-I-NBOH) is a derivative of the phenethylamine derived hallucinogen 2C-I that was discovered in 2006 by a team at Purdue University. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, making it some twelve times the potency of 2C-I itself. In vitro tests showed this compound acted as an agonist but animal studies have not been reported. While the N-benzyl derivatives of 2C-I were significantly increased in binding activity to 5HT2A receptor fragments, compared to 2C-I, the N-benzyl derivatives of DOI were less active, compared to DOI.
25I-NBOH is notable as one of the most selective agonist ligands for the 5-HT2A receptor with an EC50 value of 0.074 nM and more than 400x selectivity over the 5-HT2C receptor.

Product Name

25I-NBOH HCL

25I-NBOH HCL Specification

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