3-(DIMETHYLAMINO)PYRROLIDINE

The 3-(Dimethylamino)pyrrolidine, with CAS registry number 69478-75-7, belongs to the following product categories: (1)3-Aminopyrrolidines; (2)3-Aminopyrrolidines (Racemic). It has the systematic name of N,N-dimethylpyrrolidin-3-amine. And the chemical formula of this chemical is C₆H₁₄N_2.

Physical properties of 3-(Dimethylamino)pyrrolidine: (1)ACD/LogP: -0.42; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -4.47; (4)ACD/LogD (pH 7.4): -3.36; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 6.48 Å²; (13)Index of Refraction: 1.48; (14)Molar Refractivity: 35.28 cm³; (15)Molar Volume: 124 cm³; (16)Polarizability: 13.98×10^-24cm³; (17)Surface Tension: 31.2 dyne/cm; (18)Enthalpy of Vaporization: 39.43 kJ/mol; (19)Vapour Pressure: 2.73 mmHg at 25°C.

Uses of 3-(Dimethylamino)pyrrolidine: it can be used to produce 7-(3-dimethylamino-pyrrolidin-1-yl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid. This reaction will need reagent Et₃N. The temperature of this reaction is 100 - 110 ℃. The yield is about 84%.

When you are using this chemical, please be cautious about it as the following:
The 3-(Dimethylamino)pyrrolidine is flammable, and it may cause burns. When use it, wear suitable protective clothing, gloves and eye/face protection. If contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: N(C)(C)C1CCNC1
(2)InChI: InChI=1/C6H14N2/c1-8(2)6-3-4-7-5-6/h6-7H,3-5H2,1-2H3
(3)InChIKey: AVAWMINJNRAQFS-UHFFFAOYAT
(4)Std. InChI: InChI=1S/C6H14N2/c1-8(2)6-3-4-7-5-6/h6-7H,3-5H2,1-2H3
(5)Std. InChIKey: AVAWMINJNRAQFS-UHFFFAOYSA-N